14 December 2016 : Clinical Research
In-Depth Analysis on Influencing Factors of Adjacent Segment Degeneration After Cervical Fusion
Chaojie Yu12ABCDEF, Xiaoping Mu1ABCDEF, Jianxun Wei1CDE, Ye Chu1BE, Bin Liang1ACEG*DOI: 10.12659/MSM.902179
Med Sci Monit 2016; 22:4902-4910
Abstract
BACKGROUND: To explore the related influencing factors of adjacent segment degeneration (ASD) after cervical discectomy and fusion (ACDF).
MATERIAL AND METHODS: A retrospective analysis of 263 patients who underwent ACDF was carried out. Cervical x-ray and magnetic resonance imaging (MRI) were required before operation, after operation, and at the last follow-up. General information and some radiographic parameters of all patients were measured and recorded. According to the imaging data, patients were put into one of two groups: non-ASD group and ASD group. The differences between the two groups were compared by t-test and χ²-test, and the related influencing factors of ASD were analyzed by logistic regression.
RESULTS: In all, 138 patients had imaging ASD. Comparing the age, the postoperative cervical arc chord distance (po-CACD), and the plate to disc distance (PDD) of the two groups, differences were statistically significant (p<0.05). The gender, the fusion segment number, the pre-CACD, the pre-and-po CACD, the preoperative cervical spinal canal ratio, and the upper and lower disc height (DH) showed no statistical difference between the two groups (p>0.05). The results of logistic regression analysis showed that there were significant correlations in the following characteristics: age, postoperative po-CACD, and the PDD (p<0.05). Of all these characteristics, the correlation of age was the highest (R=1.820).
CONCLUSIONS: Age, po-CACD, and PDD were risk factors for ASD after ACDF. The older the operation age, the worse the recovery was of postoperative physiological curvature of cervical spine, and a PDD < 5 mm was more likely to lead to ASD.
Keywords: intervertebral disc degeneration, Spinal Fusion, Uterine Cervical Diseases
Editorial
01 May 2024 : Editorial
Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) – Lifileucel (Amtagvi)DOI: 10.12659/MSM.944927
Med Sci Monit 2024; 30:e944927
In Press
Clinical Research
Comparative Efficacy of Micro-Needle-Knife Therapy and Acupuncture in Acute Ankle Sprains: A Randomized Con...Med Sci Monit In Press; DOI: 10.12659/MSM.944157
Clinical Research
The Influence of Gestational Diabetes Mellitus on Maternal and Neonatal Outcomes: A Retrospective Study in ...Med Sci Monit In Press; DOI: 10.12659/MSM.943644
Clinical Research
Exploring the Educational Social and Physical Activities Among Health Care Undergraduates – a Cross-Section...Med Sci Monit In Press; DOI: 10.12659/MSM.943399
Clinical Research
Percutaneous Coronary Intervention as a Non-Surgical Treatment for Ischemic Mitral Regurgitation in Patient...Med Sci Monit In Press; DOI: 10.12659/MSM.943122
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952