Naucleamides A—E, New Monoterpene Indole Alkaloids from Nauclea latifolia

Hideyuki Shigemori; Toshinori Kagata; Haruaki Ishiyama; Frank Morah; Ayumi Ohsaki; Jun'ichi Kobayashi

doi:10.1248/cpb.51.58

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Naucleamides A—E, New Monoterpene Indole Alkaloids from Nauclea latifolia

Hideyuki Shigemori, Toshinori Kagata, Haruaki Ishiyama, Frank Morah, Ayumi Ohsaki, Jun'ichi Kobayashi

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Keywords: monoterpene indole alkaloid, naucleamide, Nauclea latifolia, spectroscopic data, amino acetal bridge

JOURNAL FREE ACCESS

2003 Volume 51 Issue 1 Pages 58-61

DOI https://doi.org/10.1248/cpb.51.58

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Abstract

Five new monoterpene indole alkaloids, naucleamides A—E (1—5), were isolated from the bark and wood of Nauclea latifolia, and the structures and relative stereochemistry were elucidated from the spectroscopic data. Naucleamide E (5) is a unique monoterpene indole alkaloid possessing a pentacyclic ring system with an amino acetal bridge.

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