Constituents of the Underground Parts of Glehnia littoralis

Zhong Yuan; Yasuhiro Tezuka; Wenzhe Fan; Shigetoshi Kadota; Xian Li

doi:10.1248/cpb.50.73

Regular Articles

Constituents of the Underground Parts of Glehnia littoralis

Zhong Yuan, Yasuhiro Tezuka, Wenzhe Fan, Shigetoshi Kadota, Xian Li

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Keywords: traditional Chinese medicine, Glehnia littoralis, lignan glycoside, neolignan glycoside, phenylpropanoid glycoside, 1,1-diphenyl-2-picrylhydrazyl radical-scavenging activity

JOURNAL FREE ACCESS

2002 Volume 50 Issue 1 Pages 73-77

DOI https://doi.org/10.1248/cpb.50.73

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Abstract

From the underground parts of Glehnia littoralis Fr. Schmidt ex Miquel (Umbelliferae), 26 compounds, including two new lignan glycosides [glehlinosides A (1) and B (2)], a new neolignan glycoside [glehlinoside C (3)], and a new phenylpropanoid glycoside [4-[β-d-apiofuranosyl-(1→6)-β-d-glucopyranosyloxy]-3-methoxypropiophenone (4)], were obtained and their structures were determined by analysis of their spectral data. The 1, 1-diphenyl-2-picrylhydrazyl radical-scavenging assay disclosed quercetin (8), isoquercetin (9), rutin (10), chlorogenic acid (11), and caffeic acid (24) as the major antioxidative constituents in this crude drug.

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