Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Lignans from Bark of Fraxinus mandshurica var. japonica and F. japonica
HIROKI TSUKAMOTOSUEO HISADASANSEI NISHIBE
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Keywords: (+)-cyclo-olivil
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1984 Volume 32 Issue 11 Pages 4482-4489

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Abstract

Three new lignans, (+)-fraxiresinol [(1S, 2R, 5R, 6S)-1-hydroxy-2-(3, 5-dimethoxy-4-hydroxyphenyl)-6-(4-hydroxy-3-methoxyphenyl)-3, 7-dioxabicyclo [3.3.0] octane] (3), (+)-1-hydroxysyringaresinol (4) and (+)-1-hydroxypinoresinol-4'-β-D-glucoside (8), and five known lignans, (+)-pinoresinol (1), (+)-1-hydroxypinoresinol (2), (-)-olivil (5), (+)-cyclo-olivil (6) and (+)-pinoresinol-β-D-glucoside (7), were isolated from the bark of Fraxinus mandshurica RUPR. var. japonica MAXIM and the bark of F. japonica BLUME (Oleaceae). Their structures were elucidated on the basis of spectroscopic analysis and chemical evidence.

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© The Pharmaceutical Society of Japan
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