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Psychiatric complications of homozygous sickle cell disease among young adults in the Jamaican Cohort Study

Published online by Cambridge University Press:  02 January 2018

Claire Hilton ,
Madeline Osborn ,
Susan Knight ,
Atul Singhal  and
Graham Serjeant
Claire Hilton*
Affiliation:
University of Manchester
Madeline Osborn
Affiliation:
Department of Psychiatry, Ysbyty Gwynedd, Bangor, Wales
Susan Knight
Affiliation:
MRC Sickle Cell Laboratories (Jamaica) and Department of Child Health, University ofthe West Indies, Kingston, Jamaica
Atul Singhal
Affiliation:
MRC Sickle Cell Laboratories (Jamaica), University of the West Indies, Kingston, Jamaica
Graham Serjeant
Affiliation:
MRC Sickle Cell Laboratories (Jamaica), University of the West Indies, Kingston, Jamaica
*
Dr C. Hilton, Elderly Services, Mental Health Services of Salford, Bury New Road, Prestwich, Manchester M25 3BL
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Abstract

Background

This study aimed to determine the prevalence of psychiatric disorder in young adults with homzygous sickle cell (SS) disease and in controls with normal haemoglobin, and to examine factors associated with psychiatric disorder.

Method

The study design was cross-sectional. Subjects were aged 18–20 years: 63 with SS disease and 89 controls. The Psychiatric Assessment Schedule was used to determine psychiatric disorder at index of Definition level 5.

Results

Psychiatric disorder was identified in 18 (29%) SS disease patients and in 22 (25%) controls. In SS patients, psychiatric disorder was not related to illness severity but was associated with leaving school early, difficulties in social adjustment, impaired cognitive function and having previous psychiatric difficulties. Male SS patients with psychiatric disorder all had low body mass index (BMI < 17.60). In controls, psychiatric disorder was associated with female gender, unemployment and difficulties in social adjustment.

Conclusions

The prevalence of psychiatric disorder was similar in patients and controls, although associated factors tended to be different. The association with low BMI in SS men merits further study.

Type
Papers
Information
The British Journal of Psychiatry , Volume 170 , Issue 1 , January 1997 , pp. 69 - 76
Copyright
Copyright © 1997 The Royal College of Psychiatrists 

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