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Macrolide and Clindamycin Resistance in Staphylococcus aureus Isolates and Antibiotic Use in a Veterans Affairs Medical Center

Published online by Cambridge University Press:  02 January 2015

Rohit Modak ,
David Ross  and
Virginia L. Kan
Rohit Modak
Affiliation:
Infectious Diseases Section, Medical Service, Veterans Affairs Medical Center, Washington, DC
David Ross
Affiliation:
Infectious Diseases Section, Medical Service, Veterans Affairs Medical Center, Washington, DC
Virginia L. Kan*
Affiliation:
Infectious Diseases Section, Medical Service, Veterans Affairs Medical Center, Washington, DC
*
Infectious Diseases Section, VA Medical Center (151B), 50 Irving St. N.W., Washington, DC 20422 (virginia.kan@va.gov)
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Abstract

A retrospective analysis of 13,946 Staphylococcus aureus isolates revealed a stable incidence of isolates that were resistant to both clindamycin and erythromycin, but a significantly increasing incidence of isolates that were susceptible to clindamycin and resistant to erythromycin during 1991-1995, 1996-2000, and 2001-2005. The use of macrolides and clindamycin also increased during 1996-2005. The incidence of S. aureus isolates with inducible clindamycin resistance increased steadily and significantly during the period from August 2004 through December 2005.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 29 , Issue 2 , February 2008 , pp. 180 - 182
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2008

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