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Transient Detection of Plasma HIV-1 RNA During Postexposure Prophylaxis

Published online by Cambridge University Press:  02 January 2015

Vincenzo Puro ,
Giuseppe Calcagno ,
Marco Anselmo ,
Gisella Benvenuto ,
Daria Trabattoni ,
Mario Clerici  and
Giuseppe Ippolito
Vincenzo Puro*
Affiliation:
IRCCS Lazzaro Spallanzani, Roma, Milano, Italy
Giuseppe Calcagno
Affiliation:
Ospedale S. Paolo, Milano, Italy
Marco Anselmo
Affiliation:
Ospedale S. Paolo, Milano, Italy
Gisella Benvenuto
Affiliation:
Ospedale S. Paolo, Milano, Italy
Daria Trabattoni
Affiliation:
Universitá degli Studi, Milano, Italy
Mario Clerici
Affiliation:
Universitá degli Studi, Milano, Italy
Giuseppe Ippolito
Affiliation:
IRCCS Lazzaro Spallanzani, Roma, Milano, Italy
*
IRCCS “Lazzaro Spallanzani, ” Centro di Riferimento AIDS, Servizio di Epidemiologia delle Malattie Infettive, Via Portuense, 292-00149 Rome, Italy
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Abstract

Transient plasma human immunodeficiency virus (HIV) copies were detected by nucleic-acid sequence-based amplification during combination antiretroviral prophylaxis in a healthcare worker who reported a percutaneous injury from a stylet and who remained HIV-antibody-negative. An HIV-specific T-helper response, assessed by interleukin-2 production, was observed when tested at 13 months following the exposure.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 21 , Issue 8 , August 2000 , pp. 529 - 531
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2000

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