Kimura's Disease associated with Ulcerative Colitis: Detection of IL-5 Mrna Expression of Peripheral Blood Mononuclear Cells and Colon Lesion.

Authors

  • M Sugaya
  • T Suzuki
  • A Asahina
  • K Nakamura
  • M Ohtsuki
  • K. Tamaki

DOI:

https://doi.org/10.1080/000155598443105

Abstract

Kimura's disease is considered to be a Th2 type allergic reaction based on the presence of eosinophilia and IgE hyperimmunoglobulinemia. We report a 26-year-old Japanese male with this disorder associated with ulcerative colitis. IL-5 is a selective stimulator for the production of eosinophilia and is considered to play an important role in Kimura's disease. IL-5 mRNA from peripheral blood mononuclear cells and the colon lesion were detected by the reverse-transcriptase polymerase chain reaction method;indicating that IL-5 can also be of importance in ulcerative colitis.

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Published

1998-10-21

How to Cite

Sugaya, M., Suzuki, T., Asahina, A., Nakamura, K., Ohtsuki, M., & Tamaki, K. (1998). Kimura’s Disease associated with Ulcerative Colitis: Detection of IL-5 Mrna Expression of Peripheral Blood Mononuclear Cells and Colon Lesion. Acta Dermato-Venereologica, 78(5), 375–377. https://doi.org/10.1080/000155598443105

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Section

Articles