Hostname: page-component-848d4c4894-x24gv Total loading time: 0 Render date: 2024-05-21T17:32:33.287Z Has data issue: false hasContentIssue false
  • English
  • Français

Transcription factor NF-κB as a potential biomarker for oxidative stress

Published online by Cambridge University Press:  09 March 2007

R. van den Berg ,
G. R. M. M. Haenen ,
H. van den Berg  and
A. Bast
R. van den Berg*
Affiliation:
TNO Nutrition and Food Research, P.O. Box 360, 3700 AJ Zeist, Netherlands Department of Pharmacology and Toxicology, Faculty of Medicine, University Maastricht, P.O. Box 616, 6200 MD Maastricht, Netherlands
G. R. M. M. Haenen
Affiliation:
Department of Pharmacology and Toxicology, Faculty of Medicine, University Maastricht, P.O. Box 616, 6200 MD Maastricht, Netherlands
H. van den Berg
Affiliation:
TNO Nutrition and Food Research, P.O. Box 360, 3700 AJ Zeist, Netherlands
A. Bast
Affiliation:
Department of Pharmacology and Toxicology, Faculty of Medicine, University Maastricht, P.O. Box 616, 6200 MD Maastricht, Netherlands
*
*Corresponding author: Dr R. van den Berg, fax +31 30 6944928, email R.vandenberg@voeding.tno.nl
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Research Article
Information
British Journal of Nutrition , Volume 86 , Issue S1 , August 2001 , pp. S121 - S127
Copyright
Copyright © The Nutrition Society 2001

References

Aupan, N, Di Donato, J, Rosette, C, Helmberg, A & Karin, M (1995) Immunosupression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis. Science 270, 286–290.Google Scholar
Baeurele, AP & Baltimore, D (1996) NF-κB: ten years after. Cell 87, 13–20.CrossRefGoogle Scholar
Bast, A (1994) Antioxidant pharmacotherapy. Drug News & Perspectives 7, 465–472.Google Scholar
Böhrer, H, Qui, F, Zimmermann, T, Zhang, Y, Jllmar, T, Männel, D, Böttiger, BW, Stern, DM, Waldherr, R, Saeger, HD, Ziegler, R, Bierhaus, A, Martin, E & Nawroth, P (1997) Role of NF-κB in the mortality of sepsis. Journal of Clinical Investigation 100, 972–985.CrossRefGoogle ScholarPubMed
Bowie, A & O’Neill, LAJ (1997) Vitamin C inhibits NF-κB activation in endothelial cells. Biochemical Society Transactions 25, 131S.CrossRefGoogle ScholarPubMed
Chen, F, Castranova, V, Shi, X & Demers, LM (1999) New insights into the role of nuclear factor-B, a ubiquitous transcription factor in the initiation of diseases. Clinical Chemistry 45, 7–17.CrossRefGoogle Scholar
Crofford, LJ, Tan, B, McCarthy, CJ & Hla, T (1997) Involvement of nuclear factor κB in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytes. Arthritis and Rheumatism 40, 226–236.CrossRefGoogle ScholarPubMed
Drent, M, van den Berg, R, Haenen, GRMM, van den Berg, H, Wouters, EFM & Bast, A (2001) NF-κB activation in sarcoidosis Sarcoidosis in press.Google Scholar
Droge, W, Schulze-Osthoff, K, Mihm, S, Galter, D, Schrenck, H, Eck, HP, Roth, S & Gmunder, H (1994) Functions of glutathione and glutatione disulfide in immunology and immunopathology. FASEB Journal 8, 1131–1138.CrossRefGoogle Scholar
Farver, CF, Raychaudhuri, B, Buhrow, LT, Connors, MJ & Thomassen, MJ (1998) Constitutive NF-κB levels in human alveolar macrophages from normal volunteers. Cytokine 10, 868–871.CrossRefGoogle ScholarPubMed
Halliwell, B & Gutteridge, JMC (1985) Free Radicals in Biology and Medicine, Oxford: Clarendon Press.Google Scholar
Hofmann, MA, Schiekofer, S, Isermann, B, Kanitz, M, Henkels, M, Joswig, M, Treusch, A, Morcos, M, Weiss, T, Borcea, V, Abdel Kalec, AKM, Amiral, J, Trischler, H, Ritz, E, Wahl, P, Ziegler, R, Bierhaus, A & Nawroth, PP (1999) Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-κB. Diabetologia 42, 222–232.CrossRefGoogle ScholarPubMed
Islam, KN, Devaraj, S & Jialal, I (1998) α-Tocopherol enrichment of monocytes decreases agonist-induced adhesion to human endothelial cells. Circulation 98, 2255–2261.CrossRefGoogle ScholarPubMed
Janssen, YMW & Sen, CK (1999) Nuclear factor κB activity in response to oxidants and antioxidants. Methods in Enzymology 300, 363–374.CrossRefGoogle ScholarPubMed
Musonda, CA & Chipman, JK (1998) Quercetin inhibits hydrogen peroxide (H2O2)-induced NF-κB DNA binding activity and DNA damage in HepG2 cells. Carcinogenesis 19, 1583–1589.CrossRefGoogle ScholarPubMed
Ritchie, ME (1999) Nuclear factor-κB is selectively and markedly activated in humans with unstable angina pectoris. Circulation 98, 1707–1713.CrossRefGoogle Scholar
Scheinman, RI, Gualberto, A, Jewell, CM, Cidlowski, JA & Balwin, AS (1995) Characterization of mechanisms involved in transrepression of NF-κB by activated glucocorticoid receptors. Molecular Cell Biology 15, 943–953.CrossRefGoogle ScholarPubMed
Schreck, R & Baeuerle, PA (1994) Assessing oxygen radicals as mediators in activation of inducible eukaryotic transcription factor NF-kappa B. Methods in Enzymology 234, 151–163.CrossRefGoogle ScholarPubMed
Schulze-Osthoff, K, Los, M & Baeuerle, PA (1995) Redox signalling by transcription factors NF-κB and AP-1 in lymphocytes. Biochemical Pharmacology 50, 735–741.CrossRefGoogle ScholarPubMed
Sen, CK & Packer, L (1996) Antioxidants and redox regulation of gene transcription. FASEB Journal 10, 709–720.CrossRefGoogle ScholarPubMed
Sen, R & Baltimore, D (1986) Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 46, 705–716.CrossRefGoogle ScholarPubMed
Siebenlist, U, Franzoso, G & Brown, K (1994) Structure, regulation and function of NF-κB. Annual Review of Cell Biology 10, 405–455.CrossRefGoogle Scholar
Suzuki, YJ, Aggarwal, BB & Packer, L (1992) Alpha-lipoic acid is a potent inhibitor of NF-κB activation in human T cells. Biochemical and Biophysical Research Communictions 189, 1709–1715.CrossRefGoogle ScholarPubMed
van den Berg, R, van Vliet, T, Broekmans, WMR, Cnubben, NHP, Vaes, WHJ, Rosa, L, Haenen, GRMM, Bast, A & van den Berg, H (2001) No effect of a vegetable/fruit concentrate with a high antioxidant capacity on biomarkers of antioxidant status in male smokers. Journal of Nutrition in press.CrossRefGoogle Scholar
Xie, QW, Kashiwabara, Y & Nathan, C (1994) Role of transcription factor NF-κB/Rel in induction of nitric oxide synthetase. Journal of Biological Chemistry 269, 4705–4708.CrossRefGoogle Scholar
Zea, AH, Ochoa, MT, Ghosh, P, Longo, DL, Alvord, WG, Valderrama, L, Falabella, R, Harvey, LK, Saravia, N, Moreno, LH & Ochoa, AC (1998) Changes in expression of signal transduction proteins in T lymphocytes of patients with leprosy. Infection and Immunity 66, 499–504.CrossRefGoogle Scholar