Download PDF
Horm Metab Res 1985; 17(8): 421-424
DOI: 10.1055/s-2007-1013563
Clinical

© Georg Thieme Verlag, Stuttgart · New York

Elevated Growth Hormone Levels in Sera from Breast Cancer Patients

Joanne T. Emerman, M. Leahy, P. W. Gout, N. Bruchovsky
  • Department of Cancer Endocrinology, Cancer Control Agency of British Columbia, Vancouver, British Columbia, Canada
Further Information

Publication History

1984

1984

Publication Date:
14 March 2008 (online)

Also available at
  PDF Download  Permissions and Reprints

Summary

The concentrations of growth hormone (GH) and prolactin (PRL) in the serum of 42 breast cancer patients were determined by radioimmunoassay (RIA). Forty percent of the patients had elevated GH levels while only 17% had elevated PRL levels. These findings suggest a relationship between GH and breast cancer; a weaker correlation exists between PRL and this malignancy. In addition, total lactogens in the serum were measured by a bioassay (BA). The BA/RIA (GH + PRL) ratio was greater in the breast cancer patients than the controls, indicating that variant forms of the hormones with higher than normal biological activity might be present.

Key-Words:

Growth hormone - Prolactin - Radio-immunoassay - Bioassay - Breast Cancer

      >