Endoscopic and Histopathologic Features of Degos' Disease

M. K. Casparie; J. W. R. Meyer; B. E. W. van Huystee; J. Kneppelhout; C. J. J. Mulder

doi:10.1055/s-2007-1010665

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Endoscopy 1991; 23(4): 231-233
DOI: 10.1055/s-2007-1010665

Endoscopic and Histopathologic Features of Degos' Disease

M. K. Casparie¹ , J. W. R. Meyer² , B. E. W. van Huystee³ , J. Kneppelhout, C. J. J. Mulder¹

¹Departments of Gastroenterology, Rijnstate Hospital, Arnhem, The Netherlands
²Departments of Pathology, Rijnstate Hospital, Arnhem, The Netherlands
³Dermatology, Rijnstate Hospital, Arnhem, The Netherlands

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Publication Date:
17 March 2008 (online)

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Abstract

The case is reported of a 69-year-old female with atrophic papules on the skin who developed multiple spontaneous intestinal perforations of which she eventually died. The skin lesions in combination with lesions in the gastrointestinal tract are typical for Degos' disease or malignant atrophic papulosis. The characteristic histopathological and endoscopic features of this rare disease are reported. This case demonstrates the importance of routinely performing endoscopy in Degos' disease to detect silent perforation, even in patients without gastrointestinal complaints.

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