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ABSTRACT

Malignant myoepitheliomas are rare tumors of salivary glands. Most occur in the parotid gland; few other sites of origin are described. Malignant myoepithelioma of the rhinopharynx has only been reported twice. Because the lesion is so rare, there are no specific indications for its treatment. We present a third case of malignant myoepithelioma in the rhinopharynx and discuss its diagnostic and therapeutic aspects.

REFERENCES

• 1 Barnes L, Appel B N, Perez H, El-Attar A M. Myoepitheliomas of the head and neck: case report and review.  J Surg Oncol. 1985;  28 21-28
  PubMedGoogle Scholar
• 2 Sciubba J J, Brannon R B. Myoepithelioma of salivary glands: report of 23 cases.  Cancer. 1982;  49 562-572
  Google Scholar
• 3 Sheldon W H. So-called mixed tumours of the salivary glands.  Arch Pathol. 1943;  35 1-20
  PubMedGoogle Scholar
• 4 Stromeyer F W, Haggitt R C, Nelson J F, Hardman J M. Myoepithelioma of minor salivary gland origin.  Arch Pathol. 1975;  99 242-245
  PubMedGoogle Scholar
• 5 Klumpp T R, Mohr R M, Silverman C L, Tang C K, Elfenbein I B, Dardick I. Malignant myoepithelioma of the parotid gland: case report and review of the literature.  J Laryngol Otol. 1995;  109 995-998
  PubMedGoogle Scholar
• 6 Chaudhry A P, Satchidanand S, Peer R, Cutler L S. Myoepithelial cell adenoma of the parotid gland: a light and ultrastructural study.  Cancer. 1982;  49 288-293
  PubMedGoogle Scholar
• 7 Kahn L B, Schoub L. Myoepithelioma of the palate. Histochemical and ultrastructural observations.  Arch Pathol. 1973;  95 209-212
  PubMedGoogle Scholar
• 8 Seifert G, Sobin L H. The World Health Organization histological classification of salivary gland tumors. A commentary on the second edition.  Cancer. 1992;  70 379-385
  PubMedGoogle Scholar
• 9 Young J, Barker M, Robertson T et al.. A case of myoepithelial carcinoma displaying biallelic inactivation of the tumour suppressor gene APC in a patient with familial adenomatous polyposis.  J Clin Pathol. 2002;  55 230-232
  PubMedGoogle Scholar
• 10 Dean A, Sierra R, Alamillos F J et al.. Malignant myoepithelioma of the salivary glands: clinicopathological and immunohistochemical features.  Br J Oral Maxillofac Surg. 1999;  37 64-66
  CrossrefPubMedGoogle Scholar
• 11 Nilles R, Lenartz T, Kaiserling E. Myoepithelial carcinoma of the nasopharynx. Case report and review of the literature.  HNO. 1993;  41 396-400
  PubMedGoogle Scholar
• 12 Tuncel U, Ergul G, Ozlugedik S, Unal A. Myoepithelial carcinoma in the nasopharynx: an unusual localization.  Yonsei Med J. 2004;  45 161-165
  PubMedGoogle Scholar
• 13 Nofal F. Spindle cell carcinoma of the nasopharynx.  J Laryngol Otol. 1983;  97 1057-1063
  PubMedGoogle Scholar
• 14 De Stefani A, Lerda W, Bussi M, Valente G, Cortesina G. Tumori dello spazio parafaringeo. Presentazione di un caso clinico di mioepitelioma a cellule chiare del lobo profondo della ghiandola parotide e revisione della letteratura.  Acta Otorhinolaryngol Ital. 1999;  19 276-282
  PubMedGoogle Scholar
• 15 Chow L T, Chow W H, Lee J C. Monomorphic epithelioid variant of malignant myoepithelioma of the parotid gland: cytologic features in fine needle aspiration (FNA).  Cytopathology. 1996;  7 279-287
  CrossrefPubMedGoogle Scholar
• 16 Torlakovic E, Ames E D, Manivel J C, Stanley M W. Benign and malignant neoplasm of myoepithelial cells: cytologic findings.  Diagn Cytopathol. 1993;  9 655-660
  PubMedGoogle Scholar
• 17 el-Naggar A, Batsakis J G, Luna M A, Goepfert H, Tortoledo M E. DNA content and proliferative activity of myoepitheliomas.  J Laryngol Otol. 1989;  103 1192-1197
  PubMedGoogle Scholar
• 18 Ibrahim R, Bird D J, Sieler M W. Malignant myoepithelioma of the larynx with massive metastatic spread to the liver: an ultrastructural and immunocytochemical study.  Ultrastruct Pathol. 1991;  15 69-76
  PubMedGoogle Scholar
• 19 Savera A T, Sloman A, Huvos A G, Klimstra D S. Myoepithelial carcinoma of the salivary glands: a clinocopathologic study of 25 patients.  Am J Surg Pathol. 2000;  24 761-774
  CrossrefPubMedGoogle Scholar
• 20 Fisch U. The infratemporal approach for nasopharyngeal tumors.  Laryngoscope. 1983;  93 36-44
  PubMedGoogle Scholar

Giuseppe MagliuloM.D. 

Via Gregorio VII n. 80

00165 Rome, Italy

Email: giuseppemagliuloorl@yahoo.com

 

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This is a well-written case report of a rare disease in a rare location. The authors ably discuss the clinical and histopathologic presentation that characterizes this rare neoplasm. Because it is unlikely that a series of such tumors in this location could be developed, a description of this patient's clinical course and the review of the existing related reports represent an especially important addition to our current literature.