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Semin Musculoskelet Radiol 1999; 3(2): 183-189
DOI: 10.1055/s-2008-1080061
© 1999 by Thieme Medical Publishers, Inc.

Bone Metastases from Soft Tissue Sarcomas

Hideki Yoshikawa1 , Akira Myoui1 , Takahiro Ochi1 , Nobuhito Araki2 , Takafumi Ueda2 , Ikuo Kudawara2 , Katsuyuki Nakanishi3 , Hisashi Tanaka3 , Hironobu Nakamura3
  • 1Department of Orthopaedic Surgery, Osaka University Medical School, Osaka, Japan
  • 2Department of Orthopaedic Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
  • 3Department of Radiology, Osaka University Medical School, Osaka, Japan
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Publication Date:
18 June 2008 (online)

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ABSTRACT

The incidence, distribution, time of appearance, and radiologic findings of bone metastases from soft tissue sarcomas, exclusive of lymphomas, were evaluated in 320 patients with soft tissue sarcomas. Thirty patients (9.4%) had evidence of 58 bone metastases. Five of 30 patients presented with metastases, and 25 of 30 patients developed metastases up to 66 months after presentation with a mean time interval of 21.3 months. The incidence of skeletal metastases differed among histologic subtypes of sarcomas; alveolar soft part sarcoma (5 of 8), dedifferentiated liposarcoma (2 of 4), angiosarcoma (2 of 4), and rhabdomyosarcoma (5 of 16) tended to show a higher incidence of bone metastases. The sarcomas metastasized to the regional bones close to the primary tumor in 16 (53%) of 30 patients and to the axial bones in 18 (60%). On conventional radiographs, the osseous metastases demonstrated predominantly osteolytic changes, and evidence of pathological fracture was observed in 31% of 58 metastases.

KEYWORDS

Metastases, MRI - metastases, radiography - tumors, soft tissue - bone, metastases

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