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Endoscopy 1991; 23(2): 73-75
DOI: 10.1055/s-2007-1010616
© Georg Thieme Verlag KG Stuttgart · New York

Site and Size of Bleeding Peptic Ulcer. Is there any Relation to the Efficacy of Hemostatic Sclerotherapy?

E. Brullet, R. Campo, G. Bedos, S. Barcons1 , J. M. Gubern1 , J. M. Bordas2
  • Endoscopy Unit, Hospital de Sabadell, Spain
  • 1Department of Surgery, Hospital de Sabadell, Spain
  • 2Hospital Clinic i Provincial de Barcelona, Spain
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Publication Date:
17 March 2008 (online)

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Summary

In 78 patients with high-risk bleeding peptic ulcers (either with active bleeding or non-bleeding visible vessel) endoscopic hemostasis by injection of adrenaline and polidocanol was attempted. Sclerotherapy was performed in 70 (90 %) patients. Initial hemostasis was achieved in 35 (94.5 %) patients with active bleeding, and permanent hemostasis in 61 (87 %). Efficacy of injection therapy was significantly lower in ulcers larger than 2 cm (p = 0.001), and in those located on the posteroinferior duodenal wall (p = 0.03). It was not possible to perform endoscopic injection in 8 (10 %) patients due to difficulty of access, lesions located mainly high on the lesser gastric curvature and on the posteroinferior duodenal wall. From these results we conclude that endoscopic injection is a very useful technique for the initial treatment of high-risk bleeding peptic ulcer, although the size and anatomical location of the lesions may be a limitation of its use.

Key words:

Endoscopicinjection - Size - Location - High-risk bleeding peptic ulcer

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