Effects of Phenolcarboxylic Acids on Superoxide Anion and Lipid Peroxidation Induced by Superoxide Anion

Shisuo Toda; Michio Kimura; Motoyo Ohnishi

doi:10.1055/s-2006-960005

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Planta Med 1991; 57(1): 8-10
DOI: 10.1055/s-2006-960005

Papers

Effects of Phenolcarboxylic Acids on Superoxide Anion and Lipid Peroxidation Induced by Superoxide Anion

Shisuo Toda, Michio Kimura, Motoyo Ohnishi

Department of Pharmaceutical Science, Institute of Medical Science, Kansai Shinkyu Medical College, 990 Ogaito, Sennan, Osaka 590-04, Japan

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Publication History

1990

Publication Date:
05 January 2007 (online)

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Abstract

The effects of phenolcarboxylic acids, caffeic acid, p-coumaric acid, and ferulic acid on the generation of superoxide anion and the production of lipid peroxide induced by superoxide anion were studied. Only ferulic acid anion among the phenolcarboxylic acids scavenged superoxide. Caffeic acid and ferulic acid inhibited lipid peroxidation induced by superoxide anion. These effects were comparable to those of superoxide dismutase or DL-α-tocopherol.

Key words

Superoxide anion - lipid peroxide production - phenolcarboxylic acids - caffeic acid - p-coumaric acid - ferulic acid - active oxygen species

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