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CC BY 4.0 · European Journal of General Dentistry 2022; 11(01): 001-006
DOI: 10.1055/s-0042-1742356
Review Article

Bioglass: A New Era in Modern Dentistry

Shruti Singh
1   Department of Conservative and Endodontics, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Maharashtra, India
,
Amit Patil
1   Department of Conservative and Endodontics, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Maharashtra, India
,
Sheetal Mali
1   Department of Conservative and Endodontics, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Maharashtra, India
,
Himmat Jaiswal
1   Department of Conservative and Endodontics, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Maharashtra, India
› Author Affiliations Funding Nil.
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Abstract

The function of biomaterials has been to replace infected or injured tissues. The first used biomaterials were bioinert, thus minimizing formation of scar tissue at the interface with host tissues. Bioglass was discovered in 1969. Larry Hench developed Bioglass 45S5, which was the earliest synthetic substance that was bonded chemically with bone. In recent researches it has appeared that Bioglass bonds with bone more readily than other bioceramics; it also indicated that the osteogenic properties are due to stimulation of osteoprogenitor cells by the dissolution products formed from Bioglass. Bioglass is chemically calcium sodium phosphosilicate, which is capable of forming an active chemical bond with the tissues. Bioglass is particularly biocompatible which, when placed in body cavity or on reacting with body stimulating factors, induces hydroxyapatite formation. This paper reviews Bioglass as a material of modern dentistry and its various applications in modern dentistry. It also discusses its composition, methods of preparation, and mechanism of action, along with its advantages and disadvantages.

Keywords

Bioglass - hydroxyapatite - broad-spectrum antimicrobial - bioactive glass - sol-gel technique

Note

We as authors have investigated:


• The ability of the nanoparticulate glass and β-tricalcium phosphate to form crystalline apatite layer on the surface of material (that is, in vitro mineralization).


• The antimicrobial efficacy of bioactive glass, tricalcium phosphate, and calcium hydroxide material.


• The preparation and characterization of nanometric bioactive glass and β-tricalcium phosphate.




Publication History

Article published online:
07 March 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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