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Symptomatic Dystonias Associated with Structural Brain Lesions: Report of 16 Cases

Published online by Cambridge University Press:  18 September 2015

Vladimir S. Kostià ,
Marina Stojanovié-Svetel  and
Aleksandra Kacar
Vladimir S. Kostià*
Affiliation:
Institute for Neurology CCS. Belgrade, Yugoslavia
Marina Stojanovié-Svetel
Affiliation:
Institute for Neurology CCS. Belgrade, Yugoslavia
Aleksandra Kacar
Affiliation:
Institute for Neurology CCS. Belgrade, Yugoslavia
*
Institute for Neurology CCS, ul. dr Subotica 6. 11000 Belgrade. Yugoslavia
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Abstract:

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Background:

Symptomatic (secondary) dystonias associated isolated lesions in the brain provide insight into etiopathogenesis of the idiopathic form of dystonia and are a basis for establishing the possible correlation between the anatomy of a lesion and the type of dystonia according to muscles affected.

Methods:

In 358 patients with differently distributed dystonias, a group of 16 patients (4.5%) was encountered in whom dystonia was associated with focal brain lesions.

Results:

Of the 16 patients, 3 patients had generalized, 3 segmental and 4 hemidystonia, while the remaining 6 patients had focal dystonia. The most frequent etiologies were infarction in 7, and tumor in 4 patients. These lesions were usually found in the lenticular and caudate nucleus, thalamus, and in the case of blepharospasm in the upper brainstem.

Conclusions:

Our results support the suggestion that dystonia is caused by a dysfunction of the basal ganglia.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 23 , Issue 1 , February 1996 , pp. 53 - 56
Copyright
Copyright © Canadian Neurological Sciences Federation 1996

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