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Coarctation of the aorta in dizygotic twins

Published online by Cambridge University Press:  19 August 2008

Monica Caldas  and
Rami Dhillon
Monica Caldas
Affiliation:
Department of Paediatric Cardiology, Royal Brompton Hospital, Sydney Street, SW3 6NP, London, United Kingdom.
Rami Dhillon*
Affiliation:
Department of Paediatric Cardiology, Royal Brompton Hospital, Sydney Street, SW3 6NP, London, United Kingdom.
*
Dr Rami Dhillon, Department of Paediatric Cardiology, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, United Kingdom. Tel: (0)171 3518542; Fax: (0)171 3518547; E-mail: r.dhillon@doctors.org.uk
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Abstract

The incidence of congenital heart disease is higher in monozygotic than dizygotic twins, with a higher concordance rate. Although coarctation of the aorta has previously been reported in monozygotic twins, to the best of our knowledge it has not been described in dizygotic twins. We report here such a concurrence in dizygotic twins conceived by in-vitro fertilisation. The finding provides support for both genetic and environmental factors in the aetiology of congenital heart disease. Furthermore, it highlights our lack of data regarding the outcome of in-vitro fertilisation.

Keywords

Congenital heart diseasecoarctation of the aortadizygotic twinsin-vitro fertilisation
Type
Brief Reports
Information
Cardiology in the Young , Volume 10 , Issue 1 , January 2000 , pp. 46 - 48
Copyright
Copyright © Cambridge University Press 2000

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