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Stage is a prognostic factor for surgically treated patients with early-stage lip cancer for whom a ‘wait and see’ policy in terms of neck status has been implemented

Published online by Cambridge University Press:  15 August 2017

G Eskiizmir ,
E Ozgur ,
G Karaca ,
P Temiz ,
N Hacioglu Yanar  and
B Cengiz Ozyurt
G Eskiizmir
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Celal Bayar University, Manisa, Turkey
E Ozgur*
Affiliation:
Department of Otolaryngology – Head and Neck Surgery Clinic, Bigadic State Hospital, Balikesir, Turkey
G Karaca
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Celal Bayar University, Manisa, Turkey
P Temiz
Affiliation:
Department of Pathology, Celal Bayar University, Manisa, Turkey
N Hacioglu Yanar
Affiliation:
Department of Otolaryngology – Head and Neck Surgery Clinic, Manisa State Hospital, Manisa, Turkey
B Cengiz Ozyurt
Affiliation:
Department of Public Health, Celal Bayar University, Manisa, Turkey
*
Address for correspondence: Dr Erdoğan Ozgur, Çavuş Gazi Blv. No: 4, 10440 Bigadiç, Balıkesir, Turkey Fax: +90 2666 141 417 E-mail: drerdoganozgur@gmail.com
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Abstract

Objectives:

To determine the locoregional control and survival rates (in terms of risk factors) of patients who underwent surgical resection of early-stage lip cancer and for whom a ‘wait and see’ policy in terms of neck status had been implemented.

Methods:

The sociodemographic data, tumour stage, tumour characteristics and histopathological features of 41 patients with early-stage lip cancer were evaluated. Factors predictive of survival and locoregional recurrence were analysed. The five-year overall survival and disease-free survival rates were determined, and the prognostic risk factors were compared.

Results:

The mean follow-up period was 60.5 months (range, 4–92 months). Age, sex, tumour stage, tumour thickness and volume, and perineural involvement were not predictive of locoregional recurrence or survival. Pathological tumour stage (T1vs T2) was a prognostic factor for both five-year overall survival (87.3 vs 65.6 per cent, p = 0.042) and disease-free survival (88.6 vs 65.6 per cent, p = 0.037).

Conclusion:

Tumour stage was clearly a major factor affecting the prognosis of surgically treated patients with early-stage lip cancer for whom a ‘wait and see’ policy in terms of neck status had been implemented.

Keywords

Lip NeoplasmsCarcinoma, Squamous CellHead And Neck NeoplasmsLocal Neoplasm RecurrencePrognosisSurvivalDisease-Free Survival
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 131 , Issue 10 , October 2017 , pp. 889 - 894
Copyright
Copyright © JLO (1984) Limited 2017 

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Footnotes

Presented at the 7th European Congress on Head and Neck Oncology, 7–10 September 2016, Budapest, Hungary.

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