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8 - Analgesia: Effects on Response to Nociceptive Stimulation

from Section 2 - Targeting Effects

Published online by Cambridge University Press:  03 December 2019

By
Emmanuel Boselli  and
Mathieu Jeanne
Edited by
Pedro L. Gambús  and
Jan F. A. Hendrickx
Pedro L. Gambús
Affiliation:
Hospital Clinic de Barcelona, Spain
Jan F. A. Hendrickx
Affiliation:
Aalst General Hospital, Belgium
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Summary

Conscious patients undergoing regional anaesthesia are able to interact with caregivers and indicate when they are feeling pain and/or anxiety during surgery. Unconscious patients on the other hand, not only in the operating room but also in intensive care, need antinociception when a nociceptive stimulus is applied. In these patients, the dose of antinociceptive drugs cannot be adjusted or the effect of locoregional anaesthesia supplementing general anaesthesia cannot be determined by simply asking the patient. Thus, the clinician needs to rely on monitors of the nociception/antinociception (N/AN) balance to be able to provide adequate, that is personalized, antinociception.

Type
Chapter
Information
Personalized Anaesthesia
Targeting Physiological Systems for Optimal Effect
 , pp. 117 - 127
Publisher: Cambridge University Press
Print publication year: 2020

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