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Clinical efficacy of linezolid in the treatment of tuberculous meningitis: a retrospective analysis and literature review

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Highlights

Retrospective study evaluating linezolid in 99 TBM patients.
Linezolid significantly reduced CSF protein levels, especially in critically ill patients.
Similar adverse event rates between groups.
Relevant literature reviews were reviewed.
Title
Clinical efficacy of linezolid in the treatment of tuberculous meningitis: a retrospective analysis and literature review
Authors
Zhen-Tao Fei
Wei Huang
Dan-Ping Zhou
Yang Yang
Ping Liu
Ning Gan
Ping-Ping He
Dan Ye
Hua-Rui Liu
Xu-Hui Liu
Lu Xia
Publication date
01-12-2025
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2025
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-025-10874-x
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Colon cancer illustration/© (M) KATERYNA KON / SCIENCE PHOTO LIBRARY / Getty Images, Human brain illustration/© (M) CHRISTOPH BURGSTEDT / SCIENCE PHOTO LIBRARY / Getty Images