Published in:

18-05-2024 | Laser | Rapid Communication

Visualizing the spatial distribution of ustalic acid in the fruiting body of Tricholoma kakishimeji

Authors: Tetsuro Ito, Syu Taira, Wataru Aoki, Hiroyuki Nagai, Masashi Fukaya, Kaori Ryu, Akiyoshi Yamada

Published in: Journal of Natural Medicines | Issue 4/2024

Abstract

Imaging mass spectrometry (IMS) was conducted for the first time using ustalic acid (UA) and the fruiting body of Tricholoma kakishimeji to localize mushroom toxins. The mushroom materials were systematically collected in Japan, and analysis of the cross sections of the materials at a resolution of 120 μm using matrix-assisted laser desorption/ionization mass spectrometry (MALDI–IMS) revealed the localization of UA and its biogenically related metabolites. MALDI–IMS confirmed that UA was predominantly located on the entire surface of the fruiting body and accumulated in higher amounts in younger fruiting bodies than in mature ones. UA is the first toxic secondary metabolite in the genus Tricholoma locally identified using IMS in mushrooms.

Graphical abstract

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Title: Visualizing the spatial distribution of ustalic acid in the fruiting body of Tricholoma kakishimeji
Authors: Tetsuro Ito
Syu Taira
Wataru Aoki
Hiroyuki Nagai
Masashi Fukaya
Kaori Ryu
Akiyoshi Yamada
Publication date: 18-05-2024
Publisher: Springer Nature Singapore
Keyword: Laser
Published in: Journal of Natural Medicines / Issue 4/2024
Print ISSN: 1340-3443
Electronic ISSN: 1861-0293
DOI: https://doi.org/10.1007/s11418-024-01823-0

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Abstract

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Isolation of C-29 oxygenated oleanane triterpenoids and a (+)-muurolene type sesquiterpenoid from the fruiting bodies of Fuscoporia torulosa and their bioactivities

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