Issue 5/2025
Content (25 Articles)
RGS14 promotes the progression of hepatocellular carcinoma by activating the cAMP/PKA/CREB signaling pathway
- Open Access
- Hepatocellular Carcinoma
- Research
Xiangnan Liang, Bin Xu, Qiuxiang Wang, Kai Gong, Chun Han, Binwen Sun, Kexin Ma, Liming Wang
Increased expression of DNAJC7 promotes the progression of hepatocellular carcinoma by influencing the cell cycle and immune microenvironment
- Open Access
- Hepatocellular Carcinoma
- Research
Jiaxing Chen, Zhizhao Yang, Yongqiang Cui, Zhilei Zhao, Dongfeng Deng, Zhihao Fu, Xiao Zhang
PSMA PET/CT for prostate cancer diagnosis: current applications and future directions
- Open Access
- Computed Tomography
- Review
Zhengang Shen, Zeng Li, Yunlong Li, Xiaodi Tang, Jiayi Lu, Li Chen, Zhu Zhong Cheng, Hong Liao, Shukui Zhou
The status and determinants of demoralization in patients with colorectal cancer: a cross-sectional study in China
- Open Access
- Colorectal Cancer
- Research
Dan Zhou, Fanfan Shi, Jie Yang, Lili Jiang, Luo Yang, Jin Wen
Repurposing tranexamic acid as an anticancer drug: a systematic review and meta-analysis
- Open Access
- Tranexamic Acid
- Review
Karoline Assifuah Kristjansen, Nulvin Djebbara-Bozo, Kumanan Rune Nanthan, Marie Louise Bønnelykke-Behrndtz
Thoracoscopy-guided thoracic paravertebral block using dexmedetomidine in combination with ropivacaine for postoperative analgesia after thoracoscopic radical resection of lung cancer: a randomized controlled trial
- Open Access
- Thoracoscopy
- Research
Ke-wei Wu, Shu-yu Deng, Xu-feng Zhang, Da-wei Zheng, Li-hong Hu
Lack of association between SLFN11 expression and treatment efficacy or survival outcomes in patients with pancreatic ductal adenocarcinoma
- Open Access
- Cytostatic Therapy
- Research
Takeaki Nakamura, Kanako C. Hatanaka, Yasuyuki Kawamoto, Shiho Kaneko, Koichi Ishida, Kazuaki Harada, Satoshi Yuki, Yoshito Komatsu, Yutaka Hatanaka, Naoya Sakamoto
Random forest-based model for the recurrence prediction of borderline ovarian tumor: clinical development and validation
- Open Access
- Fertility
- Research
Liheng Yan, Qiulin Ye, Baole Shi, Juanjuan Liu, Yuexin Hu, Ouxuan Liu, Xiao Li, Bei Lin, Yue Qi
Overexpression of KMT9α is associated with poor outcome in cholangiocarcinoma patients
- Open Access
- Cholangiocarcinoma
- Research
Maximilian N. Kinzler, Eric Metzger, Rebecca Schulz, Katrin Bankov, Anna Ramos-Triguero, Falko Schulze, Steffen Gretser, Nada Abedin, Armin Wiegering, Stefan Zeuzem, Dirk Walter, Henning Reis, Roland Schüle, Peter J. Wild
FOXM1 boosts glycolysis by upregulating SQLE to inhibit anoikis in breast cancer cells
- Open Access
- Breast Cancer
- Research
Mei Xu, Guozhi Pan, Qian Zhang, Jiangming Huang, Yehua Wu, Yashengjiang Ashan
Single-cell RNA sequencing reveals SLC31A1-mediated M2 polarization of macrophages promotes malignant progression in triple-negative breast cancer
- Open Access
- Breast Cancer
- Research
Xiwei Zhang, Guoqing Li, Tieyan Chen, Haohang Sun, Ji Dai, Qi Chen, Mengze Chen, Meidi Yan
Hereditary diffuse gastric and lobular breast cancer syndrome associated with germline CDH1 variants: focus on lobular breast cancer
- Open Access
- Breast Cancer
- Review
Giovanni Corso, Francesca Magnoni, Giorgio Bogani, Paolo Veronesi, Viviana Galimberti, Adriana Albini
Genomic profiling and pathological assessment of malignant peripheral nerve sheath tumors
- Open Access
- Sarcoma
- Research
Qian Cui, Fen Zhang, Jian Liu, Jie Xu, Hongmei Wu, Fangping Xu, Qingling Zhang
Multifocal medulloblastoma in an adult: a case report and review of the literature
- Open Access
- Medulloblastoma
- Case Report
Cha Luo, Fei Zhang, Xiaofeng Zhu, Ying Zeng, Zhonglian Wang, Hongting Jiang, Qing Ye, Wei Jian, Jing Zhang, Qiaofen Fu
High-dose vitamin C promotes mitochondrial biogenesis in HCT116 colorectal cancer cells by regulating the AMPK/PGC-1α signaling pathway
- Open Access
- Colorectal Cancer
- Research
RuiYang Hong, Su Min, Jia Huang, Mou Zou, DongYu Zhou, Yun Liang
Artificial intelligence generated 3D body composition predicts dose modifications in patients undergoing neoadjuvant chemotherapy for rectal cancer
- Open Access
- Cytostatic Therapy
- Research
Alex Besson, Ke Cao, Ahmed Mardinli, Lara Wirth, Josephine Yeung, Rory Kokelaar, Peter Gibbs, Fiona Reid, Justin M. Yeung
A comprehensive analysis of bone marrow-derived cytogenetic abnormalities in multiple myeloma patients with extramedullary disease
- Open Access
- Multiple Myeloma
- Research
Juan Xu, Haonan Yang, Jingcao Huang, Ting Niu, Chunyan Sun, Li Zhang, Yuhuan Zheng
Investigating the role of the Pon1-rs854560 (L55M) SNP in colorectal Cancer susceptibility
- Open Access
- Colorectal Cancer
- Research
Xi Wei, Rong Qin, Liang Yin, Muhammad Asad Iqbal, Zakari Shaibu, Guorui Li, Ting Wu
Integration of transcriptome-wide association study and gene-based association analysis identifies candidate genes for Hodgkin lymphoma
- Open Access
- Hodgkin Lymphoma
- Research
Wen-Hui Jia, Chang-Ling Huang, Wen-Li Zhang, Yong-Qiao He, Wen-Qiong Xue, Ying Liao, Zhi-Yang Zhao, Meng-Xuan Yang, Lu Pei, Wei-Hua Jia, Tong-Min Wang
Hemato-oncological outpatient care in medical education: a German pilot-project
- Open Access
- Hematology
- Research
Marie Forster, Sophie Winkler, Martin R. Fischer, Dirk Hempel, Valeria Milani
Efficacy and safety of the R2-MTX regimen in primary central nervous system lymphoma (PCNSL): a single-center retrospective analysis
- Open Access
- Lymphoma
- Research
Lijie Liang, Xue Meng, Li Xie, Na Li, You Feng, Ming Jiang
Preclinical pharmacokinetics and in vitro ADME properties of PAT-1102: a novel HDAC inhibitor for cancer therapy
- Open Access
- Pharmacokinetics
- Research
Chandrashekar Mataguru Doreswamy, Srinivas Seekallu, Suresh Babu Venkataramaiah, Mohan Cheluru Umesh, C. Subathra Devi
Adjuvant chemotherapy may have no significant survival benefit in older patients with stage II/III gastric cancer: a multicenter retrospective study
- Open Access
- Gastric Cancer
- Research
Zheng-Zheng Shen, En-Ze Li, Ruo-Lan Zhang, Meng-Xuan Cao, Yan-Qiang Zhang, Qing Yang, Can Hu, Si-Wei Pan, Zhi-Yuan Xu, Zai-Sheng Ye, Jing-Yang He
Retrospective comprehensive analysis of regional lymph node recurrence in breast cancer patients (REASON study)
- Open Access
- Breast Cancer
- Research
Aikaterini Liapi, Veronica Aedo-Lopez, Wendy Jeanneret-Sozzi, Athina Stravodimou, John O. Prior, Marie Nicod Lalonde, Assia Ifticene Treboux, Loic Lelievre, Lana Kandalaft, Laetitia Rossier, Audrey Goupil, Marzio Bergomi, Jean-Paul Rivals, Jean-Philippe Brouland, Elsa Curtit, Jean-Yves Meuwly, Khalil Zaman
Quality of life after risk reducing mastectomy in a Portuguese cohort of BRCA pathogenic/likely pathogenic variant carriers
- Open Access
- Breast Cancer
- Research
Maria Raposo, Bárbara Peleteiro, André Magalhães, Sandra Torres, Inês Insua-Pereira, Raquel Guimarães, Luzia Garrido, Susy Costa, José Luis Fougo