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Journal of Cancer Research and Clinical Oncology

Issue 12/2025

Content (36 Articles)

ARNT2-driven transcriptional activation of STRA6 reprograms fatty acid metabolism to promote retroperitoneal liposarcoma progression

Junxiang Zhang, Hainan Guo, Bo Ban, Lin Yang, Jie Lian, Gan Li, Lindi Cai, Kai Deng, He Jiang, Xuqi Li, Shufeng Wang

Running session-conditioned human serum lowers prostate cancer cell spheroid formation

Giulia Baldelli, Alice Avancini, Diana Giannarelli, Lorenzo Budel, Veronica Gentilini, Anita Borsati, Linda Toniolo, Asja Conti, Michele Milella, Federico Schena, Giorgio Brandi, Sara Pilotto, Mauro De Santi, Cantor Tarperi

Molecular detection of HPV, EBV, and polyomaviruses in thyroid tumors and their clinicopathological relevance

Nagwan Ramadan, Omar Alfarouk Rabiee, Mohamed M. Hafez, Nasra F. Abdel Fattah, Eman Naguib Khorshed, Khaled Khalafalla, Auhood Nassar

Retraction Note: Belinostat and panobinostat (HDACI): in vitro and in vivo studies in thyroid cancer

Daniel Chan, Yun Zheng, Jeffrey W. Tyner, Wee Joo Chng, Wen Wen Chien, Sigal Gery, Geraldine Leong, Glenn D. Braunstein, H. Phillip Koeffler

Cancer incidence trends in Baden-Württemberg (Southwest Germany) during and after the COVID-19 pandemic (2020–2023)

  • Open Access
  • Research

Lina Jansen, Silke Hermann, Susanne Bergbold, Volker Arndt

E3 ubiquitin ligase BTRC inhibits the proliferation and tumor growth of glioma cells through the NFAT5/AQP4 axis

  • Open Access
  • Research

Yexin Li, Siqiang Tang, Kaiyuan Jiang, Peng Deng, Xiqi Hu

Response to PD-1 inhibition in MMRd/MSS pancreatic ductal adenocarcinoma: the relevance of parallel testing

Heike L. Pahl, Silke Lassmann, Anne M. Schultheis, Stephan Rau, Melanie Börries, Justus Duyster, Matthias Zaiss, Michael Quante, Heiko Becker

CGREF1 promotes cancer cell migration and predicts poor prognosis in colorectal cancer

Meijun Liu, Haixia Yang, Dan Zhang, Juanzhi Chen

Quality of life following total neoadjuvant therapy for rectal cancer

Georg W. Wurschi, Markus Diefenhardt, Justus Kaufmann, Hai Minh Ha, Melanie Schneider, Daphne Schepers von Ohlen, Maren Schöneich, Adrianna Cieslak, Alina Depardon, Jan-Niklas Becker, Alexander Rühle, Felix Ehret, Maximilian Römer, Florian Rißner, Andreas Hinz, Klaus Pietschmann

Intrahepatic cholangiocarcinoma as a unique subtype: key updates from current guidelines

Aaron Schindler, Timm Denecke, Daniel Seehofer, Florian van Bömmel, Thomas Berg

Cost-effectiveness analysis of pembrolizumab versus chemotherapy in advanced non-small cell lung cancer in China based on real-world studies

Ning Wan, Chen Yang, Bing Wang, Ya Guo, ZiJian He, YaJuan Lv, LiQing Lu, Ning Yang, WeiBin Xiao, YongBang Chen, Jin Yuan, DanDan Yang, Tao Liu, WenFeng Fang, ZhuoJia Chen, WeiTing Liang

Prognostic impact of central nervous system prophylaxis and a simplified BL model in primary testicular lymphoma: a real-world multicenter study

Shuozi Liu, Ping Yang, Yu Zhao, Shaowei Zhou, Hanxi Luo, Xinan Cen, Fei Dong, Wei Wan, Hongmei Jing

Immunotherapy with and without radiotherapy following the diagnosis of bone metastasis for stage IV non-small cell carcinoma

Jeffrey Beyon, Jennifer E. Collins, Christine A. Welch, Amir Kamran

Shared decision-making in cancer care in Bangladesh: evidence from a resource-constrained setting

  • Open Access
  • Research

Md. Shahjalal, Rushabh H. Doshi, Shriya K. Garg, Kathleen Buford Cartmell, Edward Christopher Dee

Computational identification of cross-reactive TCR epitopes with ARDitox

  • Open Access
  • Research

Victor Murcia Pienkowski, Tamara Boschert, Piotr Skoczylas, Anna Sanecka-Duin, Maciej Jasiński, Bartłomiej Król-Józaga, Giovanni Mazzocco, Sławomir Stachura, Lukas Bunse, Jan Kaczmarczyk, Edward W. Green, Agnieszka Blum

Distinct immunologic kinetics and cytomegalovirus reactivation incidence with rituximab- versus obinutuzumab–bendamustine in follicular lymphoma: a single-center case series study

Matteo D’Addona, Luca Pezzullo, Lorenzo Settembre, Emilia Vaccaro, Roberto Guariglia, Bianca Serio, Laura Mettivier, Andrea Gigantiello, Giovanni Signorile, Angela Bertolini, Francesca Picone, Bianca Cuffa, Valentina Giudice, Carmine Selleri

Immune checkpoint inhibition alters patterns of failure in inoperable stage III non-small cell lung cancer patients treated with chemoradiotherapy

  • Open Access
  • NSCLC
  • Research

Julian Taugner, Silja Stamer, Kerstin Hofstetter, Chukwuka Eze, Lukas Käsmann, Kerstin Clasen, Philipp Hartig, Werner Spengler, Thorben Groß, Farkhad Manapov, Claus Belka, Maximilian Niyazi

Prognostic impact of extranodal extension in oral cavity cancers: a retrospective analysis and implications for treatment intensification

  • Open Access
  • Research

Pragyat Thakur, Vedamanasa I, Ankur Dwivedi, Tapas K. Dora, Anshul Singla, Sankalp Sancheti, Alok Goel, Ashish Gulia, Arshdeep Kaur

Fertility-sparing treatment for overweight patients with early-stage endometrial cancer or atypical endometrial hyperplasia under weight loss intervention

Mengdi Fu, Dongyan Cao, Qian Liu, Yuanli Feng, Mei Yu, Jiaxin Yang, Huimei Zhou, Ninghai Cheng, Xiangming Wu

DCN, NPM3 and SULF1 are hub genes related to vasculogenic mimicry in lung adenocarcinoma

Cheng Sun, Meifeng Ye, Weitao Cao, Jie Zeng, Zhike Liang, Yujun Li, Shuquan Wei, Zhuxiang Zhao, Ziwen Zhao

Retraction Note: Signaling network involved in the GPC3-induced inhibition of breast cancer progression: role of canonical Wnt pathway

  • Open Access
  • Retraction Note

Dolores Fernández, Macarena Guereño, María Amparo Lago Huvelle, Magalí Cercato, María Giselle Peters

Patient-reported outcomes following various incision techniques in breast reconstruction: an observational cohort study in China

Lingzi Wang, Yuhang Song, Wenqin Huang, Senyang Guo, Xinhong Wu, Hongmei Zheng

Primary hemangioblastoma of rectum: a rare case report and review of literature

Aiping Zheng, Shaojuan Zhang, Qiang Ma, Wenxu Yang, Hualiang Xiao, Xinyu Liang

Integration of RASSF1A and TSPYL5 methylation and AFP protein as plasma biomarker for hepatocellular carcinoma diagnosis

Haiyan Chen, Yingmin Luo, Linhong Li, Fei Xu, Xiaohuan Lai, Jinlong Li, Xiaomo Li, Wenjie Song, Yang Liu, Dengke Bao, Jiayun Liu, Guanlin Zhou, Shaogui Wan

Exploring the evolving role of apolipoproteins in oncology: global trends and emerging frontiers

Dianzhe Tian, Zixuan Hu, Zuyi Yang, Lvyuxing Zhao, Haitao Zhao, Xinting Sang, Shunda Du, Yunping Luo, Lei Zhang, Yiyao Xu, Xin Lu

Recent updates and future perspectives about ALDH1B1 as a potential anticancer target: a review

Tingting Zhao, Zhihong Sun, Zhenguo Li, Liujing Qu, Yulan Li, Jie Liu

Clinical application value of modified overlap anastomosis for Siewert type II and III adenocarcinoma of esophagogastric junction

Yong Fan, Linlin Hou, Han Zhang, Ruiting Zhang, Guoqing Shi, Qiuyan Li, Xingang Wang, Yuebin Wang, Qiuya Wei, Tianyu Gao

Surgical resection for pulmonary metastases from head and neck adenoid cystic carcinoma: a propensity-matched survival analysis

Zhen Yu, Xingguo Yang, Jun Wu, Xintao Yu, Jian Cui, Xiang Gao, Bobo Ma, Ji Ke, Baoxun Zhang, Xiaohong Chen, Lei Yu

Keynote webinar | Spotlight on progress in colorectal cancer

CRC remains a major global health burden, but advances in screening, treatment, and lifestyle-based prevention continue to reshape clinical practice. Gain insights into how the latest research can be leveraged to optimize patient care across the CRC continuum.

Prof. Antoni Castells
Prof. Harpreet Wasan
Prof. Edward Giovannucci
Watch now

Keynote webinar | Spotlight on functional neurological disorder

FND perplexes and frustrates patients and physicians alike. Limited knowledge and insufficient awareness delays diagnosis and treatment, and many patients feel misunderstood and stigmatized. How can you recognize FND and what are the treatment options?

Prof. Mark Edwards
Watch now
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Image Credits
Colon cancer illustration/© (M) KATERYNA KON / SCIENCE PHOTO LIBRARY / Getty Images, Human brain illustration/© (M) CHRISTOPH BURGSTEDT / SCIENCE PHOTO LIBRARY / Getty Images