Issue 1/2026
Content (43 Articles)
Research progress on ferroptosis in drug resistance and therapy of gastric cancer
- Open Access
- Gastric Cancer
- Review
Yuexin Liu, Lizhou Jia, Liu Yang, Zhang Ning, Yanmei Li
Insights into SUMOylation in gastric cancer: molecular mechanisms and emerging therapeutic opportunities
- Open Access
- Gastric Cancer
- Review
Peyman Tabnak, Mohammad Ebrahimnezhad
The c.1744G > C, p.(Glu582Gln) missense variant in coding exon 14 of APC increases skipping of a natural occurring isoform and causes Familial Adenomatous Polyposis
- Open Access
- Familial Adenomatous Polyposis
- Correspondence
Anne Marie Jelsig, Maria Bejerholm Boelman, Ulf Birkedal, Jane Hübertz, Lana Al-Zehawi, Charlotte Lautrup, John Gásdal Karstensen, Thomas van Overeem Hansen
TKI plus ICI versus ICI alone in high tumor burden hepatocellular carcinoma: a retrospective cohort study
- Open Access
- Tyrosine Kinase Inhibitors
- Research
Po-Ting Lin, Wei Teng, Wei-Ting Chen, Chung-Wei Su, Yi-Chung Hsieh, Chen-Chun Lin, Chun-Yen Lin, Shi-Ming Lin
157Gd-DHK: enhancing targeted gadolinium neutron capture for pancreatic adenocarcinoma
- Open Access
- Molecular Imaging
- Research
Liang Xie, Cuiping Song, Jialin Qin, Qianqian Xu, Jianchun Yin, Yuanyuan Ma, Hong Chen, Chao Li, Bing Hong, Ni Chen, Xiaoxi Pang
Concept and feasibility of privacy-preserving record linkage of cancer registry data and claims data in Germany: results from the DigiNet study on stage IV non-small cell lung cancer
- Open Access
- NSCLC
- Research
Anika Kästner, Christopher Hampf, Pia Naumann, Lizon Fiedler-Lacombe, Anna Kron, Anna Spier, Dusan Simic, Leonie Eilers, Aleksandra Graw, Sebastian Bartholomäus, Andreas Stang, Daniela Reil, Renate Kirschner-Schwabe, Jessica Isabel Selig, Jörg Wulff, Patrik Dröge, Thomas Ruhnke, Christian Günster, Uwe Nußbaum, Ursula Marschall, Juliane Mohnke, Anja Hebbelmann, Uwe Lührig, Anna Rasokat, Vanessa Mildenberger, Stephanie Stock, Florian Kron, Jürgen Wolf, Martin Bialke, Dana Stahl, Neeltje van den Berg, Wolfgang Hoffmann
Impact of preoperative geriatric screening and comorbidity assessment in patients with vulvar and vaginal cancer
- Open Access
- Vaginal Cancer
- Research
Valerie Catherine Linz, Emma Liebau, Markus Schepers, Katharina Gillen, Marco Johannes Battista, Michael Mohr, Mona Wanda Schmidt, Marcus Schmidt, Annette Hasenburg
Phage therapy and the microbiome in hematologic malignancies: opportunities, mechanisms, and early evidence
- Open Access
- Antibiotic
- Review
Juanwen Zhang, Jin Liu, Alireza Bayani
Efficacy and safety of neoadjuvant therapy combined with immunotherapy in MMR‑proficient/microsatellite stable non‑metastatic rectal cancer: a systematic review and meta‑analysis
- Open Access
- Rectal Cancer
- Research
Yuegang Li, Chengcheng Han, Jianqiang Tang
LAC-TME classifier: machine learning-driven model predicts survival and prioritizes targeted therapy in clear cell renal cell carcinoma
- Open Access
- Kidney Cancer
- Research
Jiawei He, Lin Qi, Yi Cai, Minfeng Chen, Yinzhao Wang
Hematological parameters as predictors of oral cancer prognosis: a systematic review and meta-analysis
- Open Access
- Biomarkers
- Review
Abdullah M. Alshahrani, Kanwalpreet Kaur, Ravinder S. Saini, Artak Heboyan
Comprehensive analysis based on spatial domains identifies CD44 as a potential target of puerarin
- Open Access
- Melanoma
- Research
Song-yang Xi, Hui Zhang, Qi-juan Wang, Yuan-jie Liu, Shu-chen Chang, Chen-fu Shi, Dong Fang, Li-hui-ping Tao, Hai-bo Cheng, Xi Zou
Quality of care before and after initial certification at a German certified hereditary breast and ovarian cancer center
- Open Access
- Ovarian Cancer
- Research
Niklas Amann, Manuel Hörner, Henrik Spannring, Lena Brückner, Julia Gocke, Carolin Müller, Cornelia Boesl, Simon Bader, Felix Heindl, Carolin C. Hack, Peter A. Fasching, Matthias W. Beckmann, Annika Krückel
TC check: a web app for thyroid cancer recurrence prediction using explainable machine learning
- Open Access
- Thyroid Cancer
- Research
Huashu Wen, Xiaohua Li, Xia Zhao
Unveiling hidden players: the role of intratumoral microbiota in gastrointestinal cancer dynamics
- Open Access
- Respiratory Microbiota
- Review
Wanfen Tang, Fakai Li, Hongjuan Zheng, Shishi Zhou, Chenhui Li, Xifeng Xu, Jianfei Fu
Safety and efficacy of zolbetuximab plus chemotherapy for claudin 18 isoform 2-positive advanced gastric cancer: initial report of real-world experience
- Open Access
- Cytostatic Therapy
- Research
Keitaro Shimozaki, Akira Ooki, Shota Fukuoka, Hiroki Osumi, Kaoru Yoshikawa, Koichiro Yoshino, Shohei Udagawa, Takeru Wakatsuki, Eiji Shinozaki, Mariko Ogura, Keisho Chin, Kensei Yamaguchi
Performance of large language models in reporting oral health concerns and side effects in head and neck cancer: a comparative study
- Open Access
- Artificial Intelligence
- Research
Jonas Rast, Susanne Wiegand, Jana Biermann, Annette Wiegand, Felix Marschner
Brahmi (Bacopa monnieri) plant preparation facilitates to enhance the activities of dendritic cells to control non-small cell lung cancer (NSCLC)
- Open Access
- NSCLC
- Research
R. Ilaya Kumar, Kavya Jain, Prashasti Arora, Harshnna Gururajan, Karan Raj Rai, Oishi Mukherjee, Melvin George, Koustav Sarkar
Neoadjuvant SBRT and intraoperative electron radiotherapy in pancreatic cancer resection
- Open Access
- Radiotherapy
- Research
Gianella Cornejo, Alon Pikarsky, Ayala Hubert, Marc Wygoda, Antoni Skripai, Aron Popovtzer, Jon Feldman, Yair Hillman, Liat Appelbaum, Mark Temper, Abed Khalaileh, Ashraf Imam, Gideon Zamir, Philip Blumenfeld
Extracellular vesicles-derived non-coding RNA in leukemias and pre-leukemic syndromes: a systematic review
- Open Access
- Acute Myeloid Leukemia
- Review
Narjes Seddighi, Malihe Najafpour, Mohammadreza Riyahi, Sepideh Mahmoudzadeh, Mehdi Talebi
Commentary on early survival gains from adding radiotherapy to ımmunotherapy in bone-metastatic NSCLC
- Open Access
- Radiotherapy
- Matters Arising
Pınar Peker
Impact of comorbidities on treatment management and prognosis in patients with anaplastic thyroid cancer (ATC)
- Open Access
- Thyroid Cancer
- Research
Teresa Augustin, Dmytro Oliinyk, Marlen Haderlein, Charlotte Frei, Julia Jacob, Daniel Medenwald, Maike Trommer, Matthias Mäurer, Sonia Drozdz, Alexander Rühle, Anca-Ligia Grosu, Nils Henrik Nicolay, Maria Waltenberger, Stephanie E. Combs, Anastassia Löser, Michael Oertel, Hans Theodor Eich, Stefan Janssen, Josefine Rauch, Ralph Gurtner, Robert Renollet, Christine Spitzweg, Dirk Vordermark, Claus Belka, Lukas Käsmann
The protective effect of probiotic therapy on gut microbiota and the activation of ω-oxidation after ovarian cancer surgery
- Open Access
- Ovarian Cancer
- Research
Chen Geng, Qingling Cao, Zhuo Chen, Xiaoyan Song, Xiaoyuan Shi
Correction: Prediction models for different types of leukemia: a systematic review and critical appraisal
- Open Access
- Leukemia
- Correction
Ayizhati Tuerxun, Yingzi Yang, Xinqi Cai, Xinyu Chen, Zhuoya Zhao, Yang Zhao, Zinuo Lin, Shengfeng Wang
Subgroup analyses of the phase 3 FOCUS study of melphalan/hepatic delivery system in patients with unresectable metastatic uveal melanoma
- Open Access
- Choroidal Melanoma
- Research
Jonathan S. Zager, Marlana Orloff, Pier Francesco Ferrucci, Junsung Choi, David J. Eschelman, Evan S. Glazer, Aslam Ejaz, Erika Richtig, Sebastian Ochsenreither, Sunil A. Reddy, Michael C. Lowe, Georgia M. Beasley, Anja Gesierich, Martin Gschnell, Reinhard Dummer, Ana Arance, Stephen William Fenwick, Joseph J. Sacco, Johnny John, Matthew Wheater, Christian H. Ottensmeier
Retraction Note: High nuclear expression of HIF1α, synergizing with inactivation of LIMD1 and VHL, portray worst prognosis among the bladder cancer patients: association with arsenic prevalence
- Open Access
- Bladder Cancer
- Retraction Note
Mukta Basu, Amvrin Chatterjee, Balarko Chakraborty, Essha Chatterjee, Sabnam Ghosh, Sudip Samadder, Dilip Kumar Pal, Anup Roy, Jayanta Chakrabarti, Amlan Ghosh, Chinmay Kumar Panda
Correction: The positive feedback loop of MAD2L1/TYK2/STAT3 induces progression in B-cell acute lymphoblastic leukaemia
- Open Access
- Acute Lymphoblastic Leukemia
- Correction
Liwen Zhu, Xinyu Li, Diandian Liu, Wenke Bai, Huaqing Yang, Qianyi Cheng, Luhong Xu, Jianpei Fang
Harnessing early postoperative MRD and VAF dynamics for precision prognosis in resected colorectal liver metastases
- Open Access
- Metastasis
- Research
Peisi Li, Tuoyang Li, Mingzhe Huang, Yiting Liu, Peiji Liu, Yuanhui Wu, Xuan Li, Rongzhao He, Yingguo Gan, Yisong Hong, Puning Wang, Jinxin Lin, Meijin Huang
Immature squamous metaplastic epithelium of Weber’s glandular duct: a significant origin of HPV-independent oropharyngeal squamous cell carcinoma in the base of the tongue
- Open Access
- Research
Xinyu Chen, Siyu Liu, Ping Li, Lin Luo, Lanzhu Lin, Qiaozhi Jiang, Dahai Yu, Renchuan Tao
Profiling and functional analysis of exosomal circRNAs from EBV-associated gastric carcinoma CSCs
- Open Access
- Epstein-Barr Virus
- Research
Li-ping Gong, Yi-ting Shao, Yu Du, Li-ping Sun, Lu-ying Tang, Jian-ning Chen
Total neoadjuvant therapy for locally advanced rectal cancer: barriers to implementation in real-world practice
- Open Access
- Rectal Cancer
- Research
David Rene Steike, Niklas Benedikt Pepper, Stefan Gravemeyer, Anne Bremer, Bernhard Glasbrenner, Matthias Brüwer, Andreas Pascher, Dirk Domagk, Lothar Biermann, Philipp Lenz, Hans Theodor Eich, Gabriele Reinartz
AI-MDT: an automatic and intelligent multidisciplinary team consultations platform for lung cancer diagnosis
- Open Access
- Lung Cancer
- Research
Yunyou Liu, Fei Wang, Peng Wang, Zhen Zhou, Hongqian Wang, Jingyao Li, Yang Qiu, Haidong Wang, Siwei Miao
Association between GRIm score and response to nivolumab monotherapy in patients with advanced malignant melanoma
- Open Access
- Melanoma
- Research
Sila Oksuz, Oguzcan Kinikoglu, Ugur Ozkerim, Deniz Isik, Heves Surmeli, Seval Ay, Utku Donem Gundogdu, Tugba Basoglu, Hatice Odabas, Nedim Turan
Long-term benefit from high-dose ifosfamide in sarcoma depends on sustained prior control and timely intervention: a machine learning analysis
- Open Access
- Sarcoma
- Research
Michael Hoberger, Romy L. Zuber, Anton Burkhard-Meier, Dorit Di Gioia, Vindi Jurinovic, Michael Völkl, Sinan E. Güler, Markus Albertsmeier, Alexander Klein, Hans Roland Dürr, Nina-Sophie Schmidt-Hegemann, Thomas Knösel, Wolfgang G. Kunz, Michael von Bergwelt-Baildon, Lars H. Lindner, Luc M. Berclaz
Type I-interferon β induces a strong anti-tumour response in bladder cancer cells
- Open Access
- Bladder Cancer
- Research
Marlena Hesse, Max Iltzsche, Daniel Nahhas, Christian Thomas, Susanne Füssel, Barbara Kind
Hypoalbuminemia as a prognostic marker for survival in biliary tract cancer: associations with tumor type, treatment and sex
- Open Access
- Gallbladder Cancer
- Research
Mostafa Abdulrazzak, Linda Björkhem-Bergman, Christina Villard, Marco Gerling, Tina Gustavell, Hannes Jansson
Acupuncture as treatment of cancer-therapy induced fatigue: a critical systematic review with a focus on the methodological assessment of blinding
- Open Access
- Acupuncture
- Review
Samuel Voigtländer, Jennifer Dörfler, Jutta Hübner
Therapeutic progress in leptomeningeal metastasis from EGFR mutant non-small cell lung cancer: a clinical medicine review
- Open Access
- NSCLC
- Review
Tianyi Ding, Yuwen Xie, Ming Ding
Initial assessments by psycho-oncologists: predictors of distress and support needs
- Open Access
- Anxiety
- Research
Viktoria Ginger, Tanja Zimmermann
Undifferentiated pleomorphic sarcoma of bone (UPSB) treated in the German-speaking countries. A report of 132 unselected patients from the Cooperative Osteosarcoma Study Group (COSS)
- Open Access
- Osteosarcoma
- Research
Stefan S. Bielack, Dimosthenis Andreou, Daniel Baumhoer, Claudia Blattmann, Godehard Friedel, Birgit Fröhlich, Semi Ben Harrabi, Leo Kager, Thekla von Kalle, Torsten Kessler, Matthias Kevric, Antonia Knoll, Thomas Kühne, Peter Reichardt, Benjamin Sorg, Reinhard Windhager, Stefanie Hecker-Nolting
Patient-reported outcomes regarding the use of complementary and alternative medicine (CAM) in BCR::ABL1-negative myeloproliferative neoplasias
- Open Access
- Research
Carl C. Crodel, Charlotte Kohnle, Markus P. Radsak, Holger Nückel, Stefanie Jilg, Andreas Hochhaus, Florian H. Heidel, Jutta Hübner
The GC-derived exosomal LncRNA DARS-AS1 activates Wnt/β-catenin pathway to drive angiogenesis by regulating miR-605-5p/BCL9
- Open Access
- Gastric Cancer
- Research
Xian Gao, Shikun Gao, Yongpu Yang, Danjie Xing, Zehao Mao, Yanlin Ren, Junjie Chen
A single-cell derived spheroid approach to dissect intratumoural heterogeneity in colorectal cancer: cell lines show changes in proteomes and therapeutic response to 5-FU
- Open Access
- Colorectal Cancer
- Research
Helene Sophia Radloff, Michael Kohl, Thorben Sauer, Sonja Hartwig, Sven Geisler, Stefan Lehr, Timo Gemoll
