Skip to main content
Key Specialties
Anesthesiology Cardiology Dermatology Diabetology Endocrinology Gastroenterology General Medicine Geriatrics Hematology Infectious Diseases Internal Medicine Nephrology Neurology Obstetrics and Gynecology Oncology Ophthalmology Pediatrics Psychiatry Radiology Respiratory Medicine Rheumatology Surgery Urology
Congress Coverage
ASH 2024 Annual Meeting 2024 ESMO Congress 2024 ERS Congress 2024 EASD Congress 2024 ESC Congress 2024 EAN Congress 2024 ASCO Annual Meeting 2024 ACC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on adolescent vaping

LIVE: Wednesday 29th January, 18:00-19:30 CET

Growing numbers of young people are using e-cigarettes, despite warnings of respiratory effects and addiction. How can doctors tackle the epidemic, and what health effects should you prepare to manage in your clinics?
ADVANCED SEARCH
Log in
Top
Critical Care
Published in:

Open Access 01-12-2024 | Isoflurane | Matters Arising

Volatile anaesthetics for ICU sedation: beyond hypnosis?

Authors: José Manuel Añón, Fernando Suarez-Sipmann, María Paz Escuela, Aris Perez-Lucendo, Andoni García-Muñoz

Published in: Critical Care | Issue 1/2024

Login to get access

Excerpt

We read the review by Müller-Wirtz [1] et al., recently published in this journal with interest. It addresses the advantages of using volatile anaesthetics for lung and diaphragm-protective sedation. As the authors point out in their methodology, it is a narrative review based on expert opinion to which we wanted to contribute with some comments we believe are important. …
Literature
1.
Müller-Wirtz LM, O´Gara B, Gama de Abreu M, Schultz MJ, Beitler JR, Jerath A, et al. Volatile anaesthetics for lung- and diaphragm-protective sedation. Crit Care. 2024;28:269.CrossRefPubMedPubMedCentral
2.
Bourgeois T, Ringot M, Ramanantsoa N, Matrot B, Dauger S, Delclaux C, et al. Breathing under anaesthesia. Anesthesiology. 2019;130:995–1006.CrossRefPubMed
3.
Yang Y, Ou M, Liu J, Zhao W, Zhuoma L, Liang Y, et al. Volatile anaesthetics activate a leak sodium conductance in retrotrapezoid nucleus neurons to maintain breathing during anaesthesia in mice. Anesthesiology. 2020;133:824–38.CrossRefPubMed
4.
Lazarenko RM, Fortuna MG, Shi Y, Mulkey DK, Takakura AC, Moreira TS, et al. Anaesthetic activation of central respiratory chemoreceptor neurons involves inhibition of a THIK-1-like background K+ current. J Neurosci. 2010;30:9324–34.CrossRefPubMedPubMedCentral
5.
Eikermann M, Malhotra A, Fassbender P, Zaremba S, Jordan AS, Gautam S, et al. Differential effects of isoflurane and propofol on upper airway dilator muscle activity and breathing. Anesthesiology. 2008;108:897–906.CrossRefPubMed
6.
Hao X, Ou M, Li Y, Zhou C. Volatile anaesthetics maintain tidal volume and minute ventilation to a greater degree than propofol under spontaneous respiration. BMC Anesthesiol. 2021;21:238.CrossRefPubMedPubMedCentral
7.
Simons JCP, Pierce E, Diaz-Gil D, Malviya SA, Meyer MJ, Timm FP, et al. Effects of depth of propofol and sevoflurane anaesthesia on upper airway collapsibility, respiratory genioglossus activation, and breathing in healthy volunteers. Anesthesiology. 2016;125:525–34.CrossRefPubMed
8.
van den Elsen MJ, Dahan A, Berkenbosch A, DeGoede J, van Kleef JW, Olievier ICW. Does subanaesthetic isoflurane affect the ventilatory response to acute isocapnic hypoxia in healthy volunteers? Anesthesiology. 1994;81:860–7.CrossRefPubMed
9.
van den Elsen M, Sarton E, Teppema L, Berkenbosch A, Dahan A. Influence of 0.1 minimum alveolar concentration of sevoflurane, desflurane and isoflurane on dynamic ventilatory response to hypercapnia in humans. Br J Anaesth. 1998;80:174–82.CrossRefPubMed
10.
Pandit JJ, Manning-Fox J, Dorrington KL, Robbins PA. Effects of subanaesthetic sevoflurane on ventilation. 2: response to acute and sustained hypoxia in humans. Br J Anaesth. 1999;83:210–6.CrossRefPubMed
11.
Pandit JJ, Manning-Fox J, Dorrington KL, Robbins PA. Effects of subanaesthetic sevoflurane on ventilation. 1: response to acute and sustained hypercapnia in humans. Br J Anaesth. 1999;83:204–9.CrossRefPubMed
12.
Lellouche F, Delorme M, Brochard L. Impact of respiratory rate and dead space in the current era of lung protective mechanical ventilation. Chest. 2020;158:45–7.CrossRefPubMed
13.
Contreras S, Giménez-Esparza C, Caballero J; Sedation, analgesia and Delirium Working Group (GTSAD) of the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC). Practical approach to inhaled sedation in the critically ill patient. Med Intensiva. 2024;48:467–76
Metadata
Title
Volatile anaesthetics for ICU sedation: beyond hypnosis?
Authors
José Manuel Añón
Fernando Suarez-Sipmann
María Paz Escuela
Aris Perez-Lucendo
Andoni García-Muñoz
Publication date
01-12-2024
Publisher
BioMed Central
Keyword
Isoflurane
Published in
Critical Care / Issue 1/2024
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-024-05163-z

Other articles of this Issue 1/2024

Outcome prediction of cardiac arrest with automatically computed gray-white matter ratio on computed tomography images

Polymyxin-containing regimens for treating of pneumonia caused by multidrug-resistant gram-negative bacteria: Mind the breakpoints and the standardization of nebulization therapy

Association between whole blood transfusion and mortality

  • Open Access
  • Matters Arising

Thiamine administration in septic shock: towards finding the target population

The role of rapid multiplex molecular syndromic panels in the clinical management of infections in critically ill patients: an experts-opinion document

Dyspnea is severe and associated with a higher intubation rate in de novo acute hypoxemic respiratory failure