Skip to main content
Top

25-09-2024 | Iron Deficiency | Short Communication

Anaemia in First Trimester: Proportion, Selected Causes and Associated Factors among First Trimester Pregnant Women Attending Antenatal Clinics in Colombo District, Sri Lanka

Authors: WR Heiyanthuduwa, KHBP Fernandopulle, CSE Goonewardena, KLMD Seneviwickrama

Published in: Indian Journal of Hematology and Blood Transfusion

Login to get access

Abstract

Purpose

To determine the proportion of anaemia and selected causes during the first trimester among pregnant women in selected Medical Officer of Health areas in Colombo District, Sri Lanka.

Methods

A descriptive cross-sectional study was conducted among 700 first trimester pregnant women attending antenatal clinics using a pretested interviewer administered questionnaire. Blood samples were collected for relevant full blood count and blood picture. Severity of anaemia was categorised using WHO cutoff values. Data was analysed using SPSS version 26.0. Logistic regression was used to identify associated factors for anaemia. Level of significance was considered as p < 0.05.

Results

The proportion of anaemia was 13.6% (mild-64.2%, moderate-34.7%, and severe-1.1%). The commonest cause of anaemia was iron deficiency (90.5%) followed by thalassemia trait 6.3%, vitamin B12/folate deficiency 1.1%, and other 2.2%.

Conclusion

Proportion of first trimester anaemia was higher than the reported prevalence in other regional studies such as in India (7.7%) and Bangladesh (10.4%). The most common cause of anaemia was iron deficiency. Findings highlight the need for early screening and intervention for anaemia among pregnant women.
Appendix
Available only for authorised users
Literature
1.
go back to reference Omotayo MO, Abioye AI, Kuyebi M, Eke AC (2021) Prenatal anemia and postpartum hemorrhage risk: A systematic review and meta-analysis. Journal of Obstetrics and Gynaecology Research [Internet]. ;47(8):2565–76. https://doi.org/10.1111/jog.14834 Omotayo MO, Abioye AI, Kuyebi M, Eke AC (2021) Prenatal anemia and postpartum hemorrhage risk: A systematic review and meta-analysis. Journal of Obstetrics and Gynaecology Research [Internet]. ;47(8):2565–76. https://​doi.​org/​10.​1111/​jog.​14834
2.
go back to reference Figueiredo AC, Gomes-Filho IS, Silva RB, Pereira PP, Da Mata FA, Lyrio AO et al (2018) Maternal anaemia and low birth weight: a systematic review and meta-analysis. Nutrients 10(5):601CrossRefPubMedPubMedCentral Figueiredo AC, Gomes-Filho IS, Silva RB, Pereira PP, Da Mata FA, Lyrio AO et al (2018) Maternal anaemia and low birth weight: a systematic review and meta-analysis. Nutrients 10(5):601CrossRefPubMedPubMedCentral
3.
go back to reference Balarajan Y, Ramakrishnan U, Özaltin E, Shankar AH, Subramanian SV (2011) Anaemia in low-income and middle-income countries. Lancet 378(9809):2123–2135CrossRefPubMed Balarajan Y, Ramakrishnan U, Özaltin E, Shankar AH, Subramanian SV (2011) Anaemia in low-income and middle-income countries. Lancet 378(9809):2123–2135CrossRefPubMed
4.
go back to reference World Health Organization (2024) Guideline on haemoglobin cutoffs to define anaemia in individuals and populations. World Health Organization World Health Organization (2024) Guideline on haemoglobin cutoffs to define anaemia in individuals and populations. World Health Organization
7.
go back to reference Pavord S, Daru J, Prasannan N, Robinson S, Stanworth S, Girling J, BSH Committee (2019) UK guidelines on the management of iron deficiency in pregnancy. Br J Haematol 188(6):819–830CrossRefPubMed Pavord S, Daru J, Prasannan N, Robinson S, Stanworth S, Girling J, BSH Committee (2019) UK guidelines on the management of iron deficiency in pregnancy. Br J Haematol 188(6):819–830CrossRefPubMed
9.
go back to reference Atreja CB, Atreja A (2020) Assessment of Iron Deficiency and Anemia in Pregnant Women. Journal of Cardiovascular Disease Research, 11(4), ISSN: 0975–3583, 0976–2833 Atreja CB, Atreja A (2020) Assessment of Iron Deficiency and Anemia in Pregnant Women. Journal of Cardiovascular Disease Research, 11(4), ISSN: 0975–3583, 0976–2833
10.
go back to reference Abeysena C, Jayawardana P (2010) Maternal haemoglobin level at booking visit and its effect on adverse pregnancy outcomes. Aust N Z J Obstet Gynaecol 50:423–427deCrossRefPubMed Abeysena C, Jayawardana P (2010) Maternal haemoglobin level at booking visit and its effect on adverse pregnancy outcomes. Aust N Z J Obstet Gynaecol 50:423–427deCrossRefPubMed
11.
go back to reference Goicoechea IO, Marcos SZ, Goicoechea MAZ, Galbete A, Alcaraz MO, Erce JAG (2022) Prevalencia De anemia en población gestante. Medicina Clínica 158(6):270–273CrossRef Goicoechea IO, Marcos SZ, Goicoechea MAZ, Galbete A, Alcaraz MO, Erce JAG (2022) Prevalencia De anemia en población gestante. Medicina Clínica 158(6):270–273CrossRef
12.
go back to reference Biradar B, Arasu S, Ramesh N (2023) Anemia burden in pregnancy and birth outcomes among women receiving antenatal care services from a secondary level hospital in South India: A record review. Journal of Family Medicine and Primary Care [Internet]. ;12(10):2352–8. https://doi.org/10.4103/jfmpc.jfmpc_2442_22 Biradar B, Arasu S, Ramesh N (2023) Anemia burden in pregnancy and birth outcomes among women receiving antenatal care services from a secondary level hospital in South India: A record review. Journal of Family Medicine and Primary Care [Internet]. ;12(10):2352–8. https://​doi.​org/​10.​4103/​jfmpc.​jfmpc_​2442_​22
13.
go back to reference Locks LM, Bhaise S, Dhurde V, Gugel A, Lauer J, Shah M et al (2024) The prevalence of anemia during pregnancy and its correlates vary by trimester and hemoglobin assessment method in Eastern Maharashtra, India. Maternal & Child Nutrition [Internet]. ; https://doi.org/10.1111/mcn.13684 Locks LM, Bhaise S, Dhurde V, Gugel A, Lauer J, Shah M et al (2024) The prevalence of anemia during pregnancy and its correlates vary by trimester and hemoglobin assessment method in Eastern Maharashtra, India. Maternal & Child Nutrition [Internet]. ; https://​doi.​org/​10.​1111/​mcn.​13684
15.
go back to reference Nwizu EN, Iliyasu Z, Ibrahim SA, Galadanci HS (2011) Socio-demographic and maternal factors in anaemia in pregnancy at booking in Kano, northern Nigeria. Afr J Reprod Health 15(4):33–41PubMed Nwizu EN, Iliyasu Z, Ibrahim SA, Galadanci HS (2011) Socio-demographic and maternal factors in anaemia in pregnancy at booking in Kano, northern Nigeria. Afr J Reprod Health 15(4):33–41PubMed
16.
go back to reference Rabindrakumar MSK, Wickramasinghe PV, Gooneratne L, Arambepola C, Senanayake H, Thoradeniya T (2018) The role of haematological indices in predicting early iron deficiency among pregnant women in an urban area of Sri Lanka. BMC Hematol 18:37CrossRefPubMedPubMedCentral Rabindrakumar MSK, Wickramasinghe PV, Gooneratne L, Arambepola C, Senanayake H, Thoradeniya T (2018) The role of haematological indices in predicting early iron deficiency among pregnant women in an urban area of Sri Lanka. BMC Hematol 18:37CrossRefPubMedPubMedCentral
17.
go back to reference Bansal A, Suri V, Sikka P, Attri SV, Varma N, Saini SS et al (2023) B12 Deficiency is the Commonest Cause of Anaemia During Pregnancy in Northern India: Study from a Tertiary Care Institute. Indian Journal of Hematology and Blood Transfusion [Internet]. ;40(1):78–82. https://doi.org/10.1007/s12288-023-01682-x Bansal A, Suri V, Sikka P, Attri SV, Varma N, Saini SS et al (2023) B12 Deficiency is the Commonest Cause of Anaemia During Pregnancy in Northern India: Study from a Tertiary Care Institute. Indian Journal of Hematology and Blood Transfusion [Internet]. ;40(1):78–82. https://​doi.​org/​10.​1007/​s12288-023-01682-x
20.
go back to reference Zhang Q, Li Z, Ananth CV (2009) Prevalence and risk factors for anaemia in pregnant women: a population-based prospective cohort study in China. Paediatr Perinat Epidemiol 23:282–291CrossRefPubMed Zhang Q, Li Z, Ananth CV (2009) Prevalence and risk factors for anaemia in pregnant women: a population-based prospective cohort study in China. Paediatr Perinat Epidemiol 23:282–291CrossRefPubMed
Metadata
Title
Anaemia in First Trimester: Proportion, Selected Causes and Associated Factors among First Trimester Pregnant Women Attending Antenatal Clinics in Colombo District, Sri Lanka
Authors
WR Heiyanthuduwa
KHBP Fernandopulle
CSE Goonewardena
KLMD Seneviwickrama
Publication date
25-09-2024
Publisher
Springer India
Published in
Indian Journal of Hematology and Blood Transfusion
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI
https://doi.org/10.1007/s12288-024-01840-9

2024 ESMO Congress

Recent advances in the use of CAR T-cell therapies in relapsed/refractory diffuse large B-cell lymphoma and follicular lymphoma

  • Webinar | 01-10-2024 | 12:30 (CEST)

Live event concluded

In this webinar, Professor Martin Dreyling and an esteemed, international panel of CAR-T experts discuss the latest data on the safety, efficacy, and clinical impact of CAR T-cell therapies in the treatment of r/r DLBCL and r/r FL.

Please note, this webinar is not intended for healthcare professionals based in the US and UK.

Sponsored by: Novartis Pharma AG

Chaired by: Prof. Martin Dreyling
Developed by: Springer Healthcare
Get a reminder for the on-demand version