Skip to main content

Advanced Search

Projected result for your current search:: 0

Search Operators:

You can use operators in your search query to narrow down your results even more. Click on the search operator to see an explanation of how it works.
Finds documents with exactly this word group, in exactly this word order and spelling (e.g. "employer branding").
Finds documents with both search terms (e.g. sales AND bonus).
Finds documents with one or the other search term (e.g. porsche OR volkswagen).
Finds documents with all search terms. Blank space is understood as AND (e.g. man robot production).
Finds documents with no appearance of the word behind NOT (e.g. ford NOT "harrison ford").
Finds documents where the search term is mentioned at least "n" times."n" may be any number (e.g. COUNT(gear)>8).
Finds documents with both search terms in any word order, permitting "n" words as a maximum distance between them. Best choose between 15 and 30 (e.g. NEAR(recruit, professionals, 20)).
Finds documents with the search term in word versions or composites. The asterisk * marks whether you wish them BEFORE, BEHIND, or BEFORE and BEHIND the search term (e.g. lightweight*, *lightweight, *lightweight*).
Finds documents with the search term in different spellings. "?" allows only one character (e.g. organi?ation).
Special characters are understood as AND (e.g. Miller Bros. & Sons).
 Log in
Top
Current Cardiology Reports

In-Stent Restenosis: Incidence, Mechanisms, and Treatment Options

Published in:
Authors
Michael Sola
Zachary Tugaoen
Jessica Willis
George A. Stouffer
Published in
Current Cardiology Reports | Issue 1/2025

Abstract

Purpose of Review

To provide an overview of up-to-date treatment practices for in-stent restenosis (ISR).

Recent Findings

ISR is treated with similar effectiveness by paclitaxel drug coated balloons and second-generation drug eluting stents. Sirolimus coated balloons are an emerging technology that requires further investigation.

Summary

The management of ISR remains challenging even with the newest generation of drug-eluting stents. The use of intravascular imaging is highly recommended to identify the mechanisms of stent failure and to tailor the method of treatment, whether it is plain old balloon angioplasty, plaque/calcium modifying tools such as intravascular lithotripsy or rotational atherectomy, additional drug eluting stents, or drug coated balloons. Paclitaxel drug coated balloons are the most recent technological advancement which has provided an option to treat ISR that doesn’t require further layers of metal. Currently, other drug coatings are being studied but it is unclear whether these balloons are as effective as paclitaxel coated balloons, with ongoing trials designed to answer this question.
Title
In-Stent Restenosis: Incidence, Mechanisms, and Treatment Options
Authors
Michael Sola
Zachary Tugaoen
Jessica Willis
George A. Stouffer
Publication date
01-12-2025
Publisher
Springer US
Published in
Current Cardiology Reports / Issue 1/2025
Print ISSN: 1523-3782
Electronic ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-025-02249-0
This content is only visible if you are logged in and have the appropriate permissions.

Other articles of this Issue 1/2025

How to Use Virtual Reality from Echocardiographic-Acquired Images

Childhood Adversity and Cardiovascular Disease; Current Knowledge and Future Directions

  • Psychological Aspects of Cardiovascular Diseases (IM Kronish and JL Birk, Section Editors)

Molecular Regulation of Cardiomyocyte Maturation

  • Regenerative Medicine (SM Wu, Section Editor)

A Body Shape Index as a Simple Anthropometric Marker for the Risk of Cardiovascular Events

  • Obesity
  • Ischemic Heart Disease (D Mukherjee, Section Editor)

Hypertension Remission After Bariatric Surgery: Metrics, Mechanisms, and Patient Selection

  • Hypertension
  • Hypertension (DS Geller and DL Cohen, Section Editors)

Cardiac Regeneration and Repair in Zebrafish and Mammalian Models

  • Open Access
  • Regenerative Medicine (SM Wu, Section Editor)

Next-generation MRI contrast agents: preparing the field (Link opens in a new window)

New MRI contrast agents are reshaping diagnostic imaging, promising lower gadolinium exposure amid evolving practice guidelines. How can you optimise contrast selection, dosing, and patient care in this rapidly advancing field?

This content is intended for healthcare professionals outside of the UK.

Independent Medical Education Grant:
  • Bayer HealthCare Pharmaceuticals Inc.
Learn more Link opens in a new window
Image Credits
Abstract graphic of layered, concentric circular shapes in bright green, pink, blue, and purple on a dark blue background. The rings and segments form a complex radial pattern without text/© Springer Health+ IME