Intratumoral calcification seems like the tree rings for tumours such as oligodendroglioma

Excerpt

Oligodendroglioma, IDH-mutant, and 1p/19q-codeleted is classified as an adult diffuse glioma in the fifth edition of the World Health Organization (WHO) Classification of Tumours of the Central Nervous System (CNS) [1]. It includes WHO grade 2 and grade 3 entities [1]. The codeletion of chromosomal arms 1p and 19q and isocitrate dehydrogenase 1 or 2 gene mutations are the main molecular biomarkers of this kind of tumour [1]. The peak age of patients with oligodendroglioma is approximately 50 years, and patients with WHO grade 2 tumours are slightly younger than those with grade 3 tumours [2]. Most tumours are located in the frontal lobe, less often in the temporal or parietal lobe, and rarely in the subtentorial area. Tumours can involve the cortex and the junctions of cortical and subcortical regions and usually present as well-defined masses. Cystic degeneration, haemorrhage, and peritumoral oedema may be observed but are relatively uncommon in grade 2 tumours [2]. Calcification is an important feature of oligodendrogliomas visible on nonenhanced computed tomography (CT) and is reported in up to 90% of cases [2, 3]. …