Skip to main content
Top

25-09-2024 | Intracranial Hypertension | Lessons Learned

A Serious Headache: Lessons Learned from the Management of Pregnancy-Associated Venous Sinus Thrombosis in a Region with Limited Abortion Access

Authors: Syed Talha Qasmi, Jacqueline Kraft, Adam Webb, Monisha A. Kumar, Catherine S. W. Albin

Published in: Neurocritical Care

Login to get access

Excerpt

A 23-year-old woman presented to the emergency department after being found unresponsive by family. On arrival she was intubated for poor Glasgow Coma Scale (GCS). The family reported that she had suffered a week of frequent vomiting and several days of severe headache. An emergent noncontrast head computed tomography (CT) scan demonstrated severe cerebral edema (Fig. 1a); a hyperdense signal within the interhemispheric fissure, concerning for acute superior sagittal sinus thrombus (Fig. 1a); and a left cerebellar hemorrhage (Fig. 1b). A CT venogram confirmed extensive cerebral venous sinus thrombosis (CVST) (Fig. 1c).
Literature
1.
go back to reference Saposnik G, Barinagarrementeria F, Brown RD Jr, Bushnell CD, Cucchiara B, Cushman M, et al., American Heart Association Stroke Council and the Council on Epidemiology and Prevention. Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011;42(4):1158–92.CrossRefPubMed Saposnik G, Barinagarrementeria F, Brown RD Jr, Bushnell CD, Cucchiara B, Cushman M, et al., American Heart Association Stroke Council and the Council on Epidemiology and Prevention. Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011;42(4):1158–92.CrossRefPubMed
2.
go back to reference Saposnik G, Bushnell C, Coutinho JM, Field TS, Furie KL, Galadanci N, et al., American Heart Association Stroke Council, Council on Cardiopulmonary, Critical Care Perioperative and Resuscitation, Council on Cardiovascular and Stroke Nursing, Council on Hypertension. Diagnosis and management of cerebral venous thrombosis: a scientific statement from the American Heart Association. Stroke. 2024;55(3):e77–90.CrossRefPubMed Saposnik G, Bushnell C, Coutinho JM, Field TS, Furie KL, Galadanci N, et al., American Heart Association Stroke Council, Council on Cardiopulmonary, Critical Care Perioperative and Resuscitation, Council on Cardiovascular and Stroke Nursing, Council on Hypertension. Diagnosis and management of cerebral venous thrombosis: a scientific statement from the American Heart Association. Stroke. 2024;55(3):e77–90.CrossRefPubMed
3.
go back to reference Ferro JM, Bousser MG, Canhão P, Coutinho JM, Crassard I, Dentali F, et al., European Stroke Organization. European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis—endorsed by the European Academy of Neurology. Eur J Neurol. 2017;24(10):1203–13.CrossRefPubMed Ferro JM, Bousser MG, Canhão P, Coutinho JM, Crassard I, Dentali F, et al., European Stroke Organization. European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis—endorsed by the European Academy of Neurology. Eur J Neurol. 2017;24(10):1203–13.CrossRefPubMed
4.
5.
go back to reference Lanska DJ, Kryscio RJ. Risk factors for peripartum and postpartum stroke and intracranial venous thrombosis. Stroke. 2000;31(6):1274–82.CrossRefPubMed Lanska DJ, Kryscio RJ. Risk factors for peripartum and postpartum stroke and intracranial venous thrombosis. Stroke. 2000;31(6):1274–82.CrossRefPubMed
6.
go back to reference Stevens SM, Woller SC, Bauer KA, Kasthuri R, Cushman M, Streiff M, et al. Guidance for the evaluation and treatment of hereditary and acquired thrombophilia. J Thromb Thrombolysis. 2016;41(1):154–64.CrossRefPubMedPubMedCentral Stevens SM, Woller SC, Bauer KA, Kasthuri R, Cushman M, Streiff M, et al. Guidance for the evaluation and treatment of hereditary and acquired thrombophilia. J Thromb Thrombolysis. 2016;41(1):154–64.CrossRefPubMedPubMedCentral
7.
go back to reference Liu K, Pei L, Gao Y, Zhao L, Fang H, Bunda B, et al. Dehydration status predicts short-term and long-term outcomes in patients with cerebral venous thrombosis. Neurocrit Care. 2019;30(2):478–83.CrossRefPubMed Liu K, Pei L, Gao Y, Zhao L, Fang H, Bunda B, et al. Dehydration status predicts short-term and long-term outcomes in patients with cerebral venous thrombosis. Neurocrit Care. 2019;30(2):478–83.CrossRefPubMed
8.
go back to reference Szecsi PB, Jørgensen M, Klajnbard A, Andersen MR, Colov NP, Stender S. Haemostatic reference intervals in pregnancy. Thromb Haemost. 2010;103(4):718–27.CrossRefPubMed Szecsi PB, Jørgensen M, Klajnbard A, Andersen MR, Colov NP, Stender S. Haemostatic reference intervals in pregnancy. Thromb Haemost. 2010;103(4):718–27.CrossRefPubMed
9.
go back to reference McLean KC, Bernstein IM, Brummel-Ziedins KE. Tissue factor-dependent thrombin generation across pregnancy. Am J Obstet Gynecol. 2012;207(2):135.e1-6.CrossRefPubMed McLean KC, Bernstein IM, Brummel-Ziedins KE. Tissue factor-dependent thrombin generation across pregnancy. Am J Obstet Gynecol. 2012;207(2):135.e1-6.CrossRefPubMed
10.
go back to reference Ross L, Solinger R. Reproductive justice: an introduction, vol. 1. Oakland: University of California Press; 2017. Ross L, Solinger R. Reproductive justice: an introduction, vol. 1. Oakland: University of California Press; 2017.
12.
go back to reference Kashkoush AI, Ma H, Agarwal N, Panczykowski D, Tonetti D, Weiner GM, et al. Cerebral venous sinus thrombosis in pregnancy and puerperium: a pooled, systematic review. J Clin Neurosci. 2017;39:9–15.CrossRefPubMed Kashkoush AI, Ma H, Agarwal N, Panczykowski D, Tonetti D, Weiner GM, et al. Cerebral venous sinus thrombosis in pregnancy and puerperium: a pooled, systematic review. J Clin Neurosci. 2017;39:9–15.CrossRefPubMed
15.
go back to reference Creanga AA, Bateman BT, Kuklina EV, Callaghan WM. Racial and ethnic disparities in severe maternal morbidity: a multistate analysis, 2008–2010. Am J Obstet Gynecol. 2014;210(5):435.e1-8.CrossRefPubMed Creanga AA, Bateman BT, Kuklina EV, Callaghan WM. Racial and ethnic disparities in severe maternal morbidity: a multistate analysis, 2008–2010. Am J Obstet Gynecol. 2014;210(5):435.e1-8.CrossRefPubMed
17.
go back to reference Mittal S, Alsbrook D, Okwechime RT, Iqbal F, Nobleza CO. The landscape of disparities in obstetric neurocritical care and a path forward. Front Neurol. 2023;13:1008544.CrossRefPubMedPubMedCentral Mittal S, Alsbrook D, Okwechime RT, Iqbal F, Nobleza CO. The landscape of disparities in obstetric neurocritical care and a path forward. Front Neurol. 2023;13:1008544.CrossRefPubMedPubMedCentral
18.
Metadata
Title
A Serious Headache: Lessons Learned from the Management of Pregnancy-Associated Venous Sinus Thrombosis in a Region with Limited Abortion Access
Authors
Syed Talha Qasmi
Jacqueline Kraft
Adam Webb
Monisha A. Kumar
Catherine S. W. Albin
Publication date
25-09-2024
Publisher
Springer US
Published in
Neurocritical Care
Print ISSN: 1541-6933
Electronic ISSN: 1556-0961
DOI
https://doi.org/10.1007/s12028-024-02122-y

Advances in Alzheimer's

Alzheimer's research and care is changing rapidly. Keep up with the latest developments from key international conferences, together with expert insights on how to integrate these advances into practice.

This content is intended for healthcare professionals outside of the UK.

Supported by:
  • Lilly
Developed by: Springer Healthcare IME
Learn more