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International Journal of Clinical Oncology

Issue 8/2025 Including Invited Reviews on Current status and perspective for palliative radiotherapy

Content (25 Articles)

PMDA regulatory update on approval and revision of the precautions for use of anticancer drugs; approval of belantamab mafodotin for multiple myeloma, asciminib for leukemia, osimertinib for lung cancer, amivantamab for lung cancer, and pembrolizumab for pleural mesothelioma in Japan

Noriomi Matsumura, Masaki Mandai

Physical activity and cancer biology: a narrative review of molecular mechanisms and introduction of the SCRUM-MONSTAR LIFELOG study

  • Open Access
  • JSCO Board of Directors Series

Shugo Yajima, Shin Kobayashi, Tadayoshi Hashimoto, Yoshiaki Nakamura, Riu Yamashita, Toshihiro Misumi, Yasutoshi Sakamoto, Satoshi Horasawa, Takao Fujisawa, Mitsuho Imai, Taro Shibuki, Yuichiro Tsukada, Hideaki Bando, Hitoshi Masuda, Takayuki Yoshino

Narrative review of focal boost to intraprostatic dominant lesion in intensity-modulated radiation therapy for localized or locally advanced prostate cancer

Rihito Aizawa, Takashi Mizowaki

Current advances and challenges in minimally invasive esophagectomy

Eisuke Booka, Hiroya Takeuchi

Escalation and de-escalation in surgery for gastric cancer

Daisuke Ichikawa, Suguru Maruyama, Hidenori Akaike, Katsutoshi Shoda, Yoshihiko Kawaguchi

Palliative radiotherapy for bone metastases: conventional external beam radiotherapy

Yuichi Kibe, Naoki Nakamura

Palliative stereotactic body radiotherapy for spinal and non-spinal bone metastases: combining tradition and innovation

Kei Ito, Naoki Nakamura

Palliative radiotherapy for painful non-bone-metastasis tumors

Tetsuo Saito

Stereotactic body radiotherapy for oligometastatic disease: current evidence and future perspectives

Nobuki Imano

Phase 1 study evaluating safety and pharmacokinetics of tusamitamab ravtansine monotherapy in Japanese patients with advanced malignant solid tumors

Kei Muro, Kentaro Yamazaki, Shigenori Kadowaki, Saori Mishima, Takeshi Kawakami, Tomoyuki Tanaka, Keisuke Tada, Nathalie Fagniez, Shinobu Ohshima, Takayuki Yoshino

Phase-Ib dose-finding and pharmacokinetic trial of metformin combined with nivolumab for refractory/recurrent solid tumors

Toshio Kubo, Hironari Kato, Shigeru Horiguchi, Toshiyuki Kozuki, Akinori Asagi, Michihiro Yoshida, Heiichiro Udono, Katsuyuki Kiura, Katsuyuki Hotta

Impact of body mass index on D-dimer diagnostic utility for deep vein thrombosis in patients with cancer: a single-center retrospective analysis

Yuya Masuda, Tatsuya Konishi, Yoshihiro Yakushijin, Shintaro Yamanaka, Shinji Hasebe, Jun Yamanouchi, Katsuto Takenaka

A randomized, double-blind, placebo-controlled phase III study evaluating the preventive effect of diclofenac cream on capecitabine-related hand-foot syndrome: study protocol of J-SUPPORT2401/JORTC-SUP06 (J-DIRECT)

Yohei Iimura, Hiroshi Ishiguro, Hironobu Hashimoto, Masanori Nojima, Shunsuke Oyamada, Keita Mori, Keisuke Ariyoshi, Seiichiro Kuroda, Satoshi Hirakawa, Noriko Fujiwara, Tomoya Yokota, Sadamoto Zenda, Hiromichi Matsuoka, Narikazu Boku

LH–RH agonist monotherapy for androgen receptor-positive recurrent and/or metastatic salivary gland cancer: a retrospective study

Takuma Kishida, Tomohiro Enokida, Ryutaro Onaga, Nobukazu Tanaka, Yuta Hoshi, Takao Fujisawa, Ryo Kuboki, Hideki Tanaka, Susumu Okano, Makoto Tahara

Impact of medications on the efficacy of immune checkpoint inhibitors in patients with recurrent or metastatic head and neck cancer

Kiyoshi Minohara, Takuma Matoba, Michi Sawabe, Daisuke Kawakita, Gaku Takano, Keisuke Oguri, Akihiro Murashima, Sho Iwaki, Hiroshi Tsuge, Sae Imaizumi, Koji Tsukamoto, Ayano Kondo, Keiichiro Shingaki, Sekai Kikuchi, Tomota Kamida, Funa Arai, Shinichi Iwasaki

Potassium-competitive acid blocker has more negative impacts on clinical outcomes in patients with non-small cell lung cancer treated with checkpoint inhibitors than those of proton pump inhibitors

Masaya Takahashi, Hitomi Nakatsukasa, Masahito Shibano, Yusuke Ishigami, Takako Oka, Yoko Tani, Tomoya Kawaguchi, Yasutaka Nakamura, Hiroyasu Kaneda

Risk factors for early mortality among patients with gastrointestinal malignancy in the C-CAT database

  • Original Article

Rei Suzuki, Hiroshi Shimizu, Kentaro Sato, Hiroyuki Asama, Rei Ohira, Mitsuru Sugimoto, Rika Saito, Maiko Okano, Reiko Kimura-Tsuchiya, Motonobu Satio, Shigehira Saji, Tadayuki Takagi, Hiromasa Ohira

Impact of cancer type differences on chemotherapy-induced nausea and vomiting (CINV) incidence in oxaliplatin-based regimens for gastric and colorectal cancer: a retrospective study

Nanaho Hiraga, Yosuke Ando, Hiroshi Matsuoka, Seira Nishibe-Toyosato, Tomohiro Mizuno, Hidetoshi Katsuno, Yoshiaki Ikeda, Kenji Kawada, Zenichi Morise, Koichi Suda, Shigeki Yamada

Impact of second-line combination chemotherapy on post-progression survival in metastatic and recurrent pancreatic cancer

Takafumi Mie, Masato Ozaka, Takeshi Okamoto, Tsuyoshi Takeda, Yoichiro Sato, Tatsuki Hirai, Takahiro Ishitsuka, Yuri Maegawa, Takaaki Furukawa, Yukari Suzuki, Takashi Sasaki, Naoki Sasahira

Percutaneous cryoablation versus robot-assisted partial nephrectomy for small renal cell carcinoma: a retrospective cost analysis at Japanese single-institution

Mayu Uka, Toshihiro Iguchi, Kensuke Bekku, Tomoaki Yamanoi, Toshiharu Mitsuhashi, Hideo Gobara, Noriyuki Umakoshi, Takahiro Kawabata, Koji Tomita, Yusuke Matsui, Motoo Araki, Takao Hiraki

Efficacy and safety of epcoritamab in Japanese patients with relapsed or refractory diffuse large B-cell lymphoma: 3-year follow-up from the EPCORE NHL-3 trial

Koji Izutsu, Takahiro Kumode, Junichiro Yuda, Hirokazu Nagai, Yuko Mishima, Youko Suehiro, Kazuhito Yamamoto, Tomoaki Fujisaki, Kenji Ishitsuka, Kenichi Ishizawa, Takayuki Ikezoe, Momoko Nishikori, Daigo Akahane, Jiro Fujita, Pegah Jafarinasabian, David Soong, Barbara D’Angelo Månsson, Ami Takahashi, Elena Favaro, Noriko Fukuhara

The prognostic factors and treatment patterns of the first recurrence of retroperitoneal liposarcoma

Yoshiyuki Matsui, Shintaro Iwata, Konosuke Moritani, Aiko Maejima, Satoshi Nara, Yukinori Yamagata, Motokiyo Komiyama, Satoshi Kamio, Kan Yonemori, Akira Kawai, Hiroyuki Fujimoto

Prognostic factors and the impact of neoadjuvant chemotherapy on the development of metastasis in patients with undifferentiated pleomorphic sarcoma of soft tissue

Shinji Miwa, Katsuhiro Hayashi, Yuta Taniguchi, Hirotaka Yonezawa, Sei Morinaga, Yohei Asano, Norio Yamamoto, Satoru Demura

Collaborative frontiers in pediatric neuro-oncology: establishing an international tumor board for enhanced care and global impact

Margaret Shatara, Nicole M. Brossier, Andrew Cluster, Ali Y. Mian, Sonika Dahiya, Amy E. Armstrong, Angela C. Hirbe, David H. Gutmann, Kenneth Aldape, Mohamed S. Abdelbaki

Systematic review and meta-analysis of photon radiotherapy versus proton beam therapy for pediatric rhabdomyosarcoma: TRP-rhabdomyosarcoma 2024

Hiroko Fukushima, Masashi Mizumoto, Sho Hosaka, Yinuo Li, Kazushi Maruo, Yoshiko Oshiro, Hazuki Nitta, Takashi Iizumi, Takashi Saito, Masako Inaba, Ryoko Suzuki, Kei Nakai, Shosei Shimizu, Hideyuki Sakurai

Jul 25
Issue: 7/2025
Sep 25
Issue: 9/2025
Including Invited Reviews on Progress in management of bone and soft tissue tumor

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Case simulations: Biomarker-driven management of NSCLC (Link opens in a new window)

Do you want to assess your biomarker testing skills and management decisions? Use these simulation-based case studies based on realistic NSCLC scenarios to do so in a practical and secure environment.

Independent Medical Education Grant:
  • Bayer HealthCare Pharmaceuticals Inc.
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How-to guide for healthcare professionals: understanding genomic reports

This educational activity was initiated, funded and co-developed by Boehringer Ingelheim and is intended for healthcare professionals in the UK and Ireland only. 

Genomic testing helps inform cancer diagnosis, prognosis, and treatment. A genomic report is generated by the laboratory carrying out next-generation sequencing to analyze biopsy samples. Access this educational microsite to learn more about typical genomic report content and how to interpret test results for patients with cancer.

NP-GB-106631 | Jan 2026

Commissioned by:
  • Boehringer Ingelheim
Learn more
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Biomarker-driven management of NSCLC logo/© Springer Health+ IME, DNA double helix structure on a purple background/© 2025 Adobe