Issue 5/2025
Content (36 Articles)
Decision analysis model of rapid versus deferred antibiotic initiation in patients with suspected sepsis in the emergency department
- Antibiotic
- Original
Terra M. Hill, Lauren T. Kerivan, Katherine A. Vilain, Sam Windham, Nima Sarani, Steven Q. Simpson, Christopher A. Guidry
Maintaining ventilation with very low tidal volume and positive-end expiratory pressure versus no ventilation during cardiopulmonary bypass for cardiac surgery in adults: a randomized clinical trial
- Open Access
- Heart Surgery
- Original
Jean-Marc Tadié, Alexandre Ouattara, Bruno Laviolle, Mathieu Lesouhaitier, Maxime Esvan, Chloé Rousseau, Murielle Grégoire, Baptiste Gaudriot, Nicolas Nesseler, François Labaste, Pascale Sanchez, Bertrand Marcheix, Antoine Beurton, Pauline Dureau, Pierre Demondion, Olivier Fouquet, Emmanuel Rineau, Julien Amour, Jean-philippe Verhoye, Alain Mercat, Nicolas Terzi, Karin Tarte, Adrien Bouglé, Erwan Flecher
Low versus high positive end expiratory pressure in noninvasive ventilation for hypoxemic respiratory failure: a multicenter randomized controlled trial
- Acute Respiratory Distress Syndrome
- Original
Jun Duan, Xiaoyi Liu, Weiwei Shu, Shijing Tian, Mingjin Yang, Mengyi Ma, Anchao Song, Qin Liu, Ke Wang, Fuxun Yang, Tao Huang, Lei Jiang, Yueling Hong, Xiaoli Han, Zhi Ao, Linfu Bai, Yiwei Min, Wenhui Hu, Jiao He
Renal tubular epithelial cells as an easily accessible biomarker for diagnosing AKI post cardiac surgery
- Acute Kidney Injury
- Original
Matthijs Oyaert, Joris Delanghe, Annelies Brouwers, Thierry Bové, Hannah Schaubroeck, Charlotte Delrue, Wim Vandenberghe, Marijn Speeckaert, Eric Hoste
Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised controlled trial
- Open Access
- Septic Shock
- Original
Akira Endo, Kazuma Yamakawa, Takashi Tagami, Yutaka Umemura, Takeshi Wada, Ryo Yamamoto, Hiroki Nagasawa, Wataru Takayama, Masayuki Yagi, Kyosuke Takahashi, Mitsuaki Kojima, Chihiro Narita, Satoshi Kazuma, Jiro Takahashi, Atsushi Shiraishi, Masaki Todani, Masaki Nakane, Toshihiko Nagata, Shohei Tanaka, Yuta Yokokawa, Kunihiko Takahashi, Haruka Ishikita, Ryo Hisamune, Junichi Sasaki, Ken-ichi Muramatsu, Hiroyuki Sonobe, Kazunobu Minami, Hiromasa Hoshi, Yasuhiro Otomo, Tomohiko Akutsu, Daiki Kaito, Hiromichi Ohsaka, Yohei Iwasaki, Fumino Taketazu, Tomoko Iguchi, Ryu Azumaguchi, Noritaka Ushio, Takahiro Okane, Toshiyuki Karumai, Ayaka Matsuoka, Chikashi Takeda, Toshiki Sera, Hiroko Okura, Yoichi Katayama, Keiichiro Shimoyama, Tadanaga Shimada, Ryuzo Abe, Tsuyoshi Nakashima, Tatsuhiko Anzai, Keisuke Suzuki, Takahiro Yamanaka, Youichi Yanagawa, Yuichi Araki
How to approach a patient hospitalized for pneumonia who is not responding to treatment?
- Open Access
- Pneumonia
- Narrative Review
Pedro Povoa, Luís Coelho, Jordi Carratala, Kelly Cawcutt, Sara E. Cosgrove, Ricard Ferrer, Carlos A. Gomez, Michael Klompas, Thiago Lisboa, Ignacio Martin-Loeches, Saad Nseir, Jorge I. F. Salluh, Sias Scherger, Daniel A. Sweeney, Andre C. Kalil
Atrial fibrillation in critical illness: state of the art
- Atrial Fibrillation
- Narrative Review
Stephanie Sibley, Jonathan Bedford, Mik Wetterslev, Brian Johnston, Tessa Garside, Salmaan Kanji, Tony Whitehouse, Ingeborg Welters, Marlies Ostermann, Martin Balik, Daniel Lancini, Blossom Dharmaraj, Emelia J. Benjamin, Allan J. Walkey, Brian H. Cuthbertson
Corticosteroids for adult patients hospitalised with non-viral community-acquired pneumonia: a systematic review and meta-analysis
- Community-Acquired Pneumonia
- Systematic Review
Tyler Pitre, Ellen Pauley, Dipayan Chaudhuri, Rohit Saha, Kristina E. Rudd, Jesús Villar, Lindsay R. Berry, Elizabeth Lorenzi, Thomas Hills, Alistair Nichol, David A. Harrison, Simon Finfer, Jeremy Cohen, John Myburgh, Naomi Hammond, Domingo Martínez, Cristina Fernández, David Antcliffe, Anthony Gordon, André Scherag, Holger Bogatsch, Frank M. Brunkhorst, Balasubramanian Venkatesh, Djillali Annane, Danny McAuley, Derek C. Angus, Bram Rochwerg, Manu Shankar-Hari
Prone positioning during veno-venous extracorporeal membrane oxygenation: a systematic review and meta-analysis
- Open Access
- ECMO
- Systematic Review
Tommaso Pettenuzzo, Eleonora Balzani, Nicolò Sella, Marco Giani, Mara Bassi, Valentina Fincati, Rossella Cescon, Giorgia Pacchiarini, Giovanna Pandolfo, Roberta Ceccato, Lars Grønlykke, Dawid L. Staudacher, Nicolas Nesseler, Senta Jorinde Raasveld, Michele Carron, Elisa Pistollato, Giulia Mormando, Francesco Zarantonello, Alessandro De Cassai, Annalisa Boscolo, Emanuele Rezoagli, Giuseppe Foti, Paolo Navalesi
Prone positioning during VV ECMO: stay on the back or not?
- ECMO
- Editorial
Asger Granfeldt, Ghislaine Douflé
Hemoadsorption in septic shock – PRO
- Septicemia
- Editorial
Marlies Ostermann, Ricard Ferrer, Thomas Rimmelé
Hemoadsorption in septic shock – CON
- Renal Replacement Procedures
- Editorial
Massimo Girardis, Martina Tosi, Sascha David
“Fake” or real hypoxia?: A brainy dilemma
- Central Nervous System Trauma
- Editorial
Mathieu van der Jagt, Chiara Robba, Mypinder Sekhon
Persistent severe AKI is bad—where to go now?
- Acute Kidney Injury
- Editorial
Zoltan Endre, Paola Rebora, Marlies Ostermann
From surface to core: does better cooling make a difference after cardiac arrest?
- Editorial
Claudio Sandroni, Louis Delamarre, Jerry P. Nolan
Bidirectional ventricular tachycardia, a very rare and severe complication of digoxin poisoning
- Digoxin
- Imaging in Intensive Care Medicine
Pablo Nicolás-Morales, Pau Torrella, Xavier Peris Cuello
A mechanism-based prognostic enrichment strategy for the development of the TREM-1 inhibitor nangibotide in septic shock
- Septic Shock
- Scientific Letter
Bruno François, Mitchell Levy, Ricard Ferrer, Pierre-François Laterre, Derek C. Angus
Diastolic dysfunction in septic patients: an alice-in-wonderland perspective on mortality impact
- Septic Shock
- Correspondence
Luigi Vetrugno, Daniele Guerino Biasucci
A critical assessment of corticosteroid trials for hospitalised patients with SARS-CoV-2 disease
- Non-Invasive Ventilation
- Scientific Letter
Jean Carlet, Didier Payen, Mervyn Singer, Michael A Matthay, Benoît Misset, Guillaume Monneret, Greet Van den Berghe
Delirium in ICU and the Macbeth’s dagger
- Delirium
- Correspondence
Dimitri Gusmao-Flores, Mariana Luz, Bruna Brandao Barreto
Delirium in ICU and Macbeth’s dagger: author’s reply
- Delirium
- Correspondence
Marcus Young, Katarzyna Kotfis, Rinaldo Bellomo
Personalized strategies for high-risk acute pulmonary embolism: addressing the “catastrophic” subgroup
- ECMO
- Correspondence
Matthieu Petit, David Levy, Matthieu Schmidt
Personalized strategies for high-risk acute pulmonary embolism: addressing the “catastrophic” subgroup. Author’s reply
- Open Access
- ECMO
- Correspondence
Sabine Hoffmann, Michael Schomaker, Leonhard Binzenhöfer, Holger Thiele, Enzo Lüsebrink
Optimizing non-intubated respiratory support in COVID-19: evaluating the impact of bundle of care strategy on awake prone positioning tolerance
- COVID-19
- Correspondence
Beilei Chen, Sheng Li
Optimizing non-intubated respiratory support in COVID-19: evaluating the impact of bundle of care strategy on awake prone positioning tolerance. Author’s reply
- Correspondence
Mariano Esperatti, Nora Fuentes, Matias Olmos
Correspondence about the VENTIBRAIN study
- Pneumonia
- Correspondence
Russell Chabanne, Claire Dahyot-Fizelier, Matthieu Jabaudon
Correspondence about the VENTIBRAIN study. Authors’ reply
- Correspondence
Giuseppe Citerio, Daniele Giardiello, Paola Rebora, Fabio S. Taccone, Chiara Robba
Left atrial reservoir strain: an essential tool for evaluating left ventricular diastolic dysfunction in 2025
- Septic Shock
- Correspondence
Christophe Beyls, Osama Abou-Arab, Yazine Mahjoub
Left atrial reservoir strain: an essential tool for evaluating left ventricular diastolic dysfunction in 2025—response. Authors’ reply
- CSF Drainage
- Correspondence
Philippe Vignon, Julien Vaidie, Marine Goudelin, Bruno Evrard
Buffering in critical illness: keeping it simple
- Metabolic Acidosis
- Correspondence
Lorenzo Giosa, Luigi Camporota, Thomas Langer
Correspondence on “Management of adult sepsis in resource-limited settings: global expert consensus statements using a Delphi method”
- Septicemia
- Correspondence
Ayooluwa O. Douglas, Kenneth T. Shelton
Balancing spontaneous ventilation and lung protection in ARDS: insights from the PC-SV trial
- Acute Respiratory Distress Syndrome
- Correspondence
Yuxian Wang, Kai Liu, Ling Zhu, Jieqiong Song, Ming Zhong
Correction: Pulmonary herpes simplex virus and cytomegalovirus in patients with acute respiratory distress syndrome related to COVID-19
- Open Access
- Human Cytomegalovirus
- Correction
Leonoor S. Boers, Frank van Someren Gréve, Jarne M. van Hattem, Justin de Brabander, Tom Zwaan, Hugo van Willigen, Marion Cornelissen, Menno de Jong, Tom van der Poll, JanWillem Duitman, Janke Schinkel, Lieuwe D. J. Bos, Paul E. Verweij, Simone J. C. F. M. Moorlag, Frank L. van de Veerdonk, Lieuwe D. J. Bos, Frank van Someren Grevé, Jeroen J. A. van Kampen, Joost Wauters, Katrien Lagrou, Simon Feys, Jannes Heylen, Michiel van Agtmael, Anne Geke Algera, Brent Appelman, Floor van Baarle, Diederik van de Beek, Martijn Beudel, Harm Jan Bogaard, Lieuwe Bos, Michela Botta, Godelieve de Bree, Matthijs C. Brouwer, Sanne de Bruin, Marianna Bugiani, Esther Bulle, David T. P. Buis, Osoul Chouchane, Alex Cloherty, Mirjam Dijkstra, Dave A. Dongelmans, Romein W. G. Dujardin, Paul Elbers, Lucas Fleuren, Suzanne Geerlings, Theo Geijtenbeek, Armand Girbes, Bram Goorhuis, Martin P. Grobusch, Laura Hagens, Jorg Hamann, Vanessa Harris, Robert Hemke, Sabine M. Hermans, Leo Heunks, Markus Hollmann, Janneke Horn, Joppe W. Hovius, Menno D. de Jong, Rutger Koning, Endry H. T. Lim, Niels van Mourik, Jeaninne Nellen, Esther J. Nossent, Frederique Paulus, Edgar Peters, Dan A. I. Piña-Fuentes, Bennedikt Preckel, Jorinde Raasveld, Tom Reijnders, Maurits C. F. J. de Rotte, Michiel Schinkel, Marcus J. Schultz, Femke A. P. Schrauwen, Alex Schuurman, Jaap Schuurmans, Kim Sigaloff, Marleen A. Slim, Patrick Smeele, Marry Smit, Cornelis S. Stijnis, Willemke Stilma, Charlotte Teunissen, Patrick Thoral, Anissa M. Tsonas, Pieter R. Tuinman, Marc van der Valk, Denise Veelo, Alexander P. J. Vlaar, Carolien Volleman, Heder de Vries, Lonneke A. Vught, Michèle van Vugt, W. Joost Wiersinga, Dorien Wouters, A. H. Zwinderman, Matthijs C. Brouwer. E. J. Nossent, J. W. Duitman, A. Saris, H. de Vries, L. J. Meijboom, L. D. J. Bos, S. G. Blok, A. R. Schuurman, T. D. Y. Reijnders, J. J. Garcia Vallejo, H. Bontkes, A. P. J. Vlaar, W. J. Wiersinga, R. Lutter, T. van der Poll, H. J. Bogaard, L. Heunks, S. Zhang, R. F. J. Kullberg, J. de Brabander, L. S. Boers
Correction: Liberal vs. restrictive transfusion strategies for acute brain injury: a systematic review and frequentist-Bayesian meta-analysis
- Correction
Pierre-Louis Blot, Maxime Renaux, Timothée Ayasse, Lucie Collet, Arthur James, Jean-Michel Constantin, Rayan Braïk
