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Inflammopharmacology

Issue 9/2025

Content (48 Articles)

The potential role of carvedilol in COVID-19 management: perspective and take-away

Hayder M. Al-Kuraishy, Maii A. Abdelnaby, Marios Papadakis, Athanasios Alexiou, Gaber El-Saber Batiha

MicroRNAs in SARS-CoV-2 infection: emerging modulators of inflammation, pathogenesis, and therapeutic potential

Mohammad Fayyad-Kazan

COVID-19 in comorbid chronic diseased patients, pregnant and lactating women: pathophysiology, available drug treatment, and the most suitable protocol regimen in each group

Hend M. Mohamed, Yara Y. Elkholy, Yara M. Mokhtar, Mirna A. Orady, Heba Sh. Elmetwaly, Hend Mo. Abdelwahab, Yasmeen S. Abdelrady, Mohamed M. Elgohary, Mohamed Kh. Elmahdy

Immuno-nutritional therapy in experimental autoimmune encephalomyelitis: a translational pathway to multiple sclerosis management

Mansur Aliyu, Ali Akbar Saboor-Yaraghi, Muhammad Ibrahim Getso, Fatema Tuz Zohora

Recent advances in the therapeutics and modes of action of a range of agents used to treat ulcerative colitis and related inflammatory conditions

Alka Patel, Parag Jain, Ajazuddin

Parkinson’s disease: genetics and neuroinflammatory insights

Isha Chandel, Shilpa Kumari, Kajal Bagri, Amit Bhatia, Rahul Deshmukh

Therapeutic potential of luteolin in neurodegenerative disorders: targeting Nrf2, NFĸB, MAPK, and JAK-STAT pathways to combat neuroinflammation and apoptosis

Koleshwar Mahto, Omkar Kumar Kuwar, Aayushi Maloo, Nileshwar Kalia

The link between oral health and neurodegeneration: a review of periodontitis in Alzheimer’s and Parkinson’s disease and dementia

Pooja Wagaskar, Sayali Gaikwad, Meghraj Suryawanshi, Ashwani Patil

The renin–angiotensin system (RAS) and arthritic diseases: therapeutic potential for RAS inhibitors

Yasser H. Habib, Mahmoud Khattab, Mennatallah A. Gowayed

Efficacy and safety of celecoxib in schizophrenia: a systematic review and meta-analysis of randomized controlled trials

NourAllah Farag, Abdullah Selim, Osama Hassan, Hamdy A. Makhlouf, Mahmoud Soliman, Lamees Taman, Omar Kassar

Effects of Nigella sativa and its constituents on inflammatory markers in ovalbumin-induced asthma model: a preclinical systematic review and meta-analysis

Hassan Ghobadi, Elmira Mohammadzadeh, Mohammad Reza Aslani

Therapeutic potential of Boswellia serrata in arthritis management: mechanistic insights into COX-2, 5-LOX, and NFĸB modulation

Koleshwar Mahto, Omkar Kumar Kuwar, Aayushi Maloo, Abhishek Kumar

A systematic review of natural products targeting Nrf2-Keap1-ARE pathway and their influence on neurodegenerative disorders

Sharmila Gote, Sonal Dubey, Shachindra L. Nargund, Shankar Thapa

Unlocking therapeutic potential in traumatic brain injury: exploring microenvironmental targets, signaling pathways and translational hurdles

Deepankar Bahuguna, Etikala Amulya, Shristi Arya, Soham Loharkar, Ganesh Vambhurkar, Saptarshee Bhattacharjee, Dinesh Kumar Chandanapalli, Jitender Madan, Saurabh Srivastava

Pharmacotherapeutic potential of daidzein: insights into mechanisms and clinical relevance

Chinchu Praisthy LJ, Ravi Kushwah, Sachin Dubey, Vipin Kumar, Smita Jain

Transforming advancing autosomal dominant polycystic kidney disease care: investigating new horizons in treatment and research

Komal Thapa, Heena Khan, Amarjot Kaur, Thakur Gurjeet Singh

The protective effects of coenzyme Q10 on blood pressure: a narrative review of anti-inflammatory and antioxidant mechanisms

Seyed Mohammad Hosseini Roknabadi, Amirmohammad Abolhassani, Erfan Davoodi, Fatemeh Zahra Moghaddam Rad, Sadegh Jafarnejad

Unlocking the molecular pathway of atopic dermatitis: journey so far and roads ahead

Sourabh Kumar, Rohit Sharma, Kumari Komal, Dinesh Kumar, Rashmi Ghosh, Manish Kumar

The IL-12 family cytokines in neurodegenerative diseases: dual roles in neurotoxicity and neuroprotection

Pouya Goleij, Alireza Amini, Pantea Majma Sanaye, Mohammad Mahdi Heidari, Mohammad Amin Khazeei Tabari, Michael Aschner, Danaé S. Larsen, Haroon Khan, Maria Daglia

Regulation of toll-like receptor signaling pathways in age-related eye disease: from mechanisms to targeted therapeutics

Qiaoqiao Kong, Yixiang Jiang, Xiang Li, Xuejing Lu

Bioenergetic failure and oxidative stress: mitochondrial contributions to Alzheimer’s disease

Rufaida Wasim

Modulation of inflammatory and oxidative stress pathways by polyphenol-rich Pleurospermum candollei extract in carrageenan-induced paw edema in rats

Mehreen Fatima, Muhammad Rashid Khan, Motrih Al-Mutiry, Mitesh Patel, Nawaf Alshammari, Mohd Adnan

Anti-IBD activity of Eleusine indica through inhibition of TNF-alpha and p38 MAPK expression

Otomo Ohene-Bekoe, Michael Hagan, Kofi Oduro Yeboah, Bernard Elikplim Petershie, Aaron Opoku Antwi, Newman Osafo

Intra-articular hexagonal boron nitride–hyaluronic acid composite hydrogels rebalance cytokine profiles and enhance extracellular matrix regeneration in a rabbit osteoarthritis model

Ezgi Kar, Fatih Kar, Yapıncak Göncü, Gökçe Mehmet Ay, Aykut Küçükbaş, Cansu Özbayer, Dilek Burukoğlu Dönmez, Cansu Arslan, Hakan Şentürk, Nusret Köse, Nuran Ay

Protective effects of ozone therapy on cartilage degeneration in temporomandibular joint osteoarthritis

Tássia T. Machado, Ana Carolina S. Machado, Catarine M. Nishijima, Cleverton Roberto de Andrade, Sílvio Roberto Consonni, Lizandra M. de Sousa, Carlos A. Parada, Cláudia H. Tambeli

Mulberroside A ameliorates murine allergic airway inflammation by suppressing Th2 response and oxidative stress

Chian-Jiun Liou, Shu-Ju Wu, Shu-Chen Cheng, Wen-Chung Huang

Mitigation of inflammation and oxidative stress in FCA-induced arthritic rat model through gum acacia intervention: a comprehensive in‑vivo study

Sobia Khalid Awan, Ali Sharif, Bushra Akhtar

Orange peel extract and hesperidin attenuate myeloperoxidase activity and oxidative stress in vitro, with anti-inflammatory effects in vivo: a natural approach to gingival protection

Tinhinane Rekeb, Samia Bedouhene, Nassima Senani, Sahra-Amel Belambri, Meriem-Dehbia Chabane, Kahina Ladj, Riadh Ksouri, Pham My-Chan Dang, Jamel El Benna

Alphonsea elliptica (Hook.f. and Thomson) methanol leaves extract obliterates inflammatory processes in LPS-induced human plasma

Ali Attiq, Juriyati Jalil, Sheryar Afzal, Waqas Ahmad

Veratric acid and zinc: a synergistic approach to accelerated wound healing in rats

  • Original Article

Rumila Afzal, Sidra Kaleem, Aslam Khan, Fareeha Anwar, Umair Ilyas, Alaa S. Alhegaili, Mansoor Ali, Sajid Ali

Sunitinib treatment reduces proinflammatory cytokine levels and mortality rates by suppressing the NLRP3 inflammasome signaling pathway in sepsis

Ahmet Kucuk, Nurhak Aksungur, Zekai Halici, Taha Tavaci, Mustafa Ozkaraca, Behzat Tebrizi

Cucurbitacin B alleviates DSS-induced experimental colitis by targeting ZNF70 to suppress the NLRP3/STAT3 signaling axis

Shen Cao, Yuhan Wang, Yi Tai, Jing Han, Yanjin Zheng, Can Wang, Hong Xiang Zuo, Ming Yue Li, Yue Xing, Xuejun Jin, Juan Ma

Longitudinal relationships between changes in post-COVID mental fatigue and neuropsychiatric symptoms across distinct recovery trajectories

  • Open Access
  • Fatigue
  • Original Article

Wenrui Bao, Siyuan Chen, Ningkun Hong, Gengchen Ye, Chiyin Li, Jingmei Xie, Peng Li, Heng Li, Yang Wang, Jixin Liu, Xuan Niu, Yuchen Zhang

A systems biology approach reveals dual neurotherapeutic mechanisms of Dioscorea bulbifera in Alzheimer’s disease via estrogen signaling and cholinergic modulation

Mayank Roy Chowdhury, Sudarshana Deepa Vijaykumar

Evaluation of antioxidant, anti-inflammatory, and analgesic potentials of combined polyphenol-rich fractions from Ziziphus mauritiana and Ziziphus spina-christi leaves through modulation of inflammatory and oxidative stress markers in Sprague Dawley rats model

Bader Alsuwayt

Phytochemical studies of Veitchia arecina Becc. leaves with evaluation of in-vitro, in-vivo anti-inflammatory, and wound healing properties in rats

  • Open Access
  • Original Article

Radwa S. Emad, Rasha A. Attia, Mona Fekry, Nesreen M. I. M. Elkomy, Tarek M. Ibrahim, Amal A. Al-Gendy

Tectoridin modulates intertwined molecular pathways in metabolic syndrome: insights from network pharmacology, molecular docking, and in vivo studies

  • Original Article

Ashwini Kumar Mishra, Pravat Kumar Sahoo, Rajesh Singh, Smita Jain

Therapeutic potential of alpha-lipoic acid on mitochondrial dynamics, oxidative/nitrosative stress, and histopathological changes in rat ulcerative colitis model

İrem Taner, Nur Banu Bal, Saadet Özen Akarca Dizakar, Veysel Bay, Mürşide Ayşe Demirel

The effects of ellagic acid in metabolic dysfunction-associated steatotic liver disease (MASLD) patients: a randomized, add-on, double-blind, controlled trial

Mohammad Mahmoudi Azar, Matin Shirazinia, Mohsen Nematy, Vafa Baradaran Rahimi, Motahare Bateni, Fateme Tafaghodi Piadeh Gheibi, Farnood Rajabzadeh, Ladan Goshayeshi, Sara Honari, Mehran Mottahedi, Vahid Reza Askari

Anti-inflammatory effects of 6-gingerol on arthritis in rats by inhibition of the NF-kB TAB1 signaling pathway

Xueming Yao, Qiuyi Wang, Xuemei Yuan, Feng Luo, Yi Ling, Changming Chen, Wukai Ma

Correction: Tetramethylpyrazine alleviates hepatic fibrosis induced by experimental mansonic schistosomiasis

Ana Carolina Campos dos Santos, Daniel Figueiredo-Vanzan, Josiane Bentes, Juliana Maria Motta, Hilton Antônio Mata-Santos, Alexandre dos Santos Pyrrho, Morgana Teixeira Lima Castelo-Branco

Correction: Tectoridin modulates intertwined molecular pathways in metabolic syndrome: insights from network pharmacology, molecular docking, and in vivo studies

Ashwini Kumar Mishra, Pravat Kumar Sahoo, Rajesh Singh, Smita Jain

Retraction Note: Anti-rheumatic activity of pseudoephedrine (a substituted phenethylamine) in complete Freund’s adjuvant-induced arthritic rats by down regulating IL-1β, IL-6 and TNF-α as well as upregulating IL-4 and IL-10

Haseeb Ahsan, Hafiz Muhammad Irfan, Alamgeer, Muhammad Shahzad, Mulazim Hussain Asim, Muhammad Akram, Muhammad Shoaib Zafar

Retraction Note: Effects of Chrysophyllum albidum fruit pulp on haemodynamic parameters, pro-inflammatory markers, antioxidant parameters and critical biomolecules associated with hypertension–in vivo

  • Retraction Note

Folake Lucy Oyetayo, Seun Funmilola Akomolafe, Gbemisola Beulah Balogun

Retraction Note: Polystichum braunii extracts inhibit Complete Freund’s adjuvant-induced arthritis via upregulation of I-κB, IL-4, and IL-10, downregulation of COX-2, PGE2, IL-1β, IL-6, NF-κB, and TNF-α, and subsiding oxidative stress

Ammara Saleem, Mohammad Saleem, Muhammad Furqan Akhtar, Muhammad Shahzad, Shah Jahan

Retraction Note: Assessment of antiarthritic potential of Asparagus dumosus using formaldehyde and CFA-induced arthritic models in rats via modulation of oxidative stress biomarkers and mRNA expression of IL-1b, IL-6, RANKL, OPG, TNF-α and COX-2

  • Retraction Note

Nimra Nazar, Malik Hassan Mehmood, Rida Siddique, Muhammad Naeem Faisal

Retraction Note: Novel glycoside from Wedelia calendulacea inhibits diethyl nitrosamine-induced renal cancer via downregulating the COX-2 and PEG2 through nuclear factor-κB pathway

Amita Verma, Bahar Ahmed, Firoz Anwar, Mahfoozur Rahman, Dinesh Kumar Patel, Gaurav Kaithwas, Ravi Rani, Prakash C. Bhatt, Vikas Kumar

Retraction Note: Glimepiride mitigates tauopathy and neuroinflammation in P301S transgenic mice: role of AKT/GSK3β signaling

Mennatallah O. Zaki, S. El-Desouky, Doaa A. Elsherbiny, Mohamed Salama, Samar S. Azab

Aug 25
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