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Inflammopharmacology

Issue 8/2025

Content (41 Articles)

Phytochemical modulation of mTOR signaling: emerging nanotechnology-driven therapeutics for rheumatoid arthritis management

Deepa Mandlik, Prapti Adgaonkar, Satish Mandlik

Advancing osteoarthritis management: integrating new insights and addressing persistent roadblocks

Aditi Kaushik, Vrinda Gupta, Manish Kaushik, Amardeep Ankalgi, M. S. Ashawat, C. P. S. Verma, Deewakar Baral

Neuroprotective effects of rutin in ischemic stroke: a review

Ali Mohammad Pourbagher-Shahri, Fatemeh Forouzanfar, Ehsan Saburi, Hanie Mahaki

Berberine as a natural immunomodulator of B lymphocytes

Saeed Mohammadian Haftcheshmeh, Maryam Musavi, Shadi Lotfi, Anvar Soleimani, Masoumeh Dodangeh, Asadollah Mohammadi, Amir Abbas Momtazi-Borojeni

New insights on pharmacological potential of montelukast: a comprehensive review

Karan Goel, Dhirendra Singh, Rajat Goyal, Seema Bansal, Sukhbir Singh, Neelam Sharma, Sumeet Gupta

A systematic review of the role of interleukin inhibitors in lichen planus: therapeutic and paradoxical effects

Amirhossein Heidari, Fatemeh Fathabadi, Kimia Ghanavati, Asma Rasouli, Sanaz Soleimani, Nazila Heidari

Psoriatic arthritis in transition: cytokine signaling, immune dysregulation, and therapeutic innovation

Sanjana Sahu, Parag Jain, Rohitas Deshmukh, Pradeep Kumar Samal, Trilochan Satapathy, Ajazuddin

Immunopharmacology of senescence: targeting the senescence-associated secretory phenotype (SASP)—a mechanism-based review

  • Review

Poonam Sahu, Trilochan Satapathy

Asperuloside as a promising multi-target agent for Alzheimer’s disease: molecular mechanisms and therapeutic perspectives

Kanika Vashisht, Himanshu Kumar, Amardeep Ankalgi, Mahendra Singh Ashawat, Rimpi, Shiv Kumar Kushawaha, Ashish Baldi

Traumatic Brian Injury (TBI) unraveled: molecular disruptions and therapeutic avenues

Nisha Kumari, Kajal Bagri, Shilpa Kumari, Rahul Deshmukh

Phytotherapeutic insights into hyperuricemia: a mechanistic and clinical perspective

Kanika Kaushal, Nishant Goutam, Abhishashi Sharma, Shivani

From the Amazon to modern pharmacology: medicinal plants as metabolic and cardiovascular modulators in cardiodiabesity

  • Review

Bruno Portela Dias, Henrick Vinícius Prado Dantas, João de Barros Neto, Thiago Afonso Carvalho Celestino Teixeira, Heitor Ribeiro da Silva, Erdi Can Aytar, José Carlos Tavares Carvalho

Semaphorin-3A in autoimmune rheumatic diseases: immunological and pathological aspects

Ramin Lotfi, Hoda Rahmani, Alireza Nasirifar

Targeting JAK/STAT signaling pathway by curcumin: implications for spinal cord injury neuroprotection

Abroumand Gholami Arman, Fatemeh Tahmasebi, Hossein Haghir, Hamideh Babaloo

Deciphering the iridoids' boundaries: from soil ecology to anti-inflammatory medicines

  • Review

M. V. N. L. Chaitanya, Hemanth Kumar Manikyam, Neerugatti Dora Babu, Sachin Kumar Singh, Avijit Mazumder, Sanjesh Kumar, Ramanjireddy Tatiparthi, T. Prabha, Sakshi Sharma

Insights into ion channels to identify drug target for neuropathic pain management

Shiwani Sharma, Priyanka Rana, Neelima Dhingra, Tanzeer Kaur

Chemokine receptor type-5: a key regulator of immunity, disease pathogenesis, and emerging therapeutic target

Vaishali Bambal, Priyanka Kodihalli Basavaraj, Kenchappa Vanaja

Anti-arthritic and immunomodulatory effects of geniposide: a systematic review and meta-analysis of preclinical studies

Muhammad Muzammil Nazir, Asma Ashraf, Muhammad Mubashir Nazir, Mohammad Rameez Hashmi

Modulating endoplasmic reticulum stress and NLRP3 inflammasome in polycystic ovary syndrome: a review of natural and synthetic compounds

Arfah Siddiqua, Abdul Malik, Urooj Iqbal

Polyphenolic protection: the role of mangiferin in mitigating neurodegeneration and neuroinflammation

  • Open Access
  • Review

Aya M. Mustafa, Ghadir A. Bastawesy, Shymaa Hatem, Roxane Abdel-Gawad Moussa, Dina M. Hal, Mariam H. Fawzy, Mahmoud A. Mansour, Mohamed S. Abd El Hafeez

Therapeutic potential of melatonin-induced mitophagy in the pathogenesis of Alzheimer’s disease

Pouya Goleij, Mohammad Amin Khazeei Tabari, Mohadeseh Poudineh, Pantea Majma Sanaye, Haroon Khan, Alan Prem Kumar, Danaé S Larsen, Maria Daglia

Antidiabetic drugs in Parkinson’s disease: a comprehensive meta-analysis on efficacy and safety with trial sequential analysis and GRADE evaluation

Amr M. Abou Elezz, Kareem Khalefa, Ahmed Farid Gadelmawla, Youssef A. Khattab, Mohamed Abo Zeid

Recent advancement in molecular pathways and receptor targeting using natural products for wound healing activity

Ankita Sinha, Parag Jain, Ajazuddin

Associations of genetic proxies for non-steroidal anti-inflammatory drugs with increased kidney stone risk: a Mendelian randomization study

  • Open Access
  • Original Article

Junfa Liu, Kaiyi Dong, Gang Qin, Chunyan Ye, Jinghan Wu, E. Wang, Zhitao Dong

Therapeutic efficacy of celastrol in experimental polyarthritis: insights from a meta-analysis of in vivo studies

Muhammad Muzammil Nazir, Iqra Farzeen, Asma Ashraf

Is dolichol pathway dysfunction a significant factor in Alzheimer’s disease?

John V. Schloss

The use of statins can reduce the risk of osteoarthritis and osteoporosis

Xin Zeng, Fei Luo, Xiao-dong Wang, Wan-jun Cao, Yong-jie Chen, Qiang Su

Safety profile of glucokinase activator AZD1656: systematic review and meta-analysis of 23 randomised trials in diabetic and healthy volunteers with relevance to immunomodulatory therapy

Mohamed M. Elsayed, Mohamed M. Abdalla

Stabilizing effect of green tea extract and epigallocatechin-3-gallate (EGCG) on mast cell : an in vivo study

Md. Mominul Islam, Nadiah Syafiqah Nor Azman, Sreemoy kanti Das, Mohd Gousuddin, Md. Abu Hasan Rasel, Md. Robiul Islam, Nadia Izbeta Bini

Antioxidative and anti-inflammatory effects of Carvacrol against polycystic ovary syndrome associated complications using high fat diet and Letrozole challenged rat model: a multidisciplinary study cascading in vivo, in vitro, in silico and network pharmacology approaches

Arfah Siddiqua, Abdul Malik, Urooj Iqbal, Nabeela Tabassum Sial, Malik Hassan Mehmood, Muhammad Fayyaz ur Rehman

Intact glycoconjugates from Taenia crassiceps excreted/secreted products ameliorate chemically induced colitis by modulating inflammation and strengthening adherens junctions

Yadira Ledesma-Soto, Ilse Chávez-Soto, Marissa Calderón-Torres, Andrea Monserrat Rodríguez-Lozoya, Jonadab E. Olguin, Luis B. Hernández-Portilla, César M. Flores-Ortíz, Fernando Candanedo, Miriam Rodriguez-Sosa, Sonia E. Hernández-Navia, Luis I. Terrazas

Neuroinflammation and metabolic dysregulation as predictors of cognitive impairment, depression, and quality of life in type 2 diabetes mellitus patients on SGLT2 inhibitors and sulfonylureas

Haya Majid, Sajad Ul Islam, Sunil Kohli, Nidhi

A novel in vivo adjuvant activity of hydrocarbon isolated from Hippophae rhamnoides

Himanshi Tanwar, Shruti Shukla, Lilly Ganju

Anti-inflammatory and gastroprotective effects of Fagonia bruguieri var. laxa (Zygophyllaceae) via attenuating biochemical alterations and cellular damage in experimental animals

  • Original Article

Faraza Javaid, Humaira Gul, Farhan Mukhtar, Salman Farsi, Sana Ghafoor, Hafiza Maida Arshad

Synaptamide regulates astroglial functional activity after cerebral cortex injury

Igor Manzhulo, Anastasia Egoraeva, Darya Ivashkevich, Olga Manzhulo, Arina Ponomarenko

Fenchone attenuates CD68-dependent 7-ketocholesterol accumulation, cholesterol dyshomeostasis and inflammatory responses via modulation of macrophage polarization

Sangeetha Ravi, Livya Catherene Martin, Manikandan Kumaresan, Jaya Suriya Mani, Beulaja Manikandan, Manikandan Ramar

Is ibuprofen associated with upper gastrointestinal bleeding? A systematic review and meta-analysis

Konstantinos Gkiouras, Ioannis Myrogiannis, Dimitrios Kouvelas

Exploring the potential of Moringa oleifera seed extract-loaded microemulsion hydrogel in the DNCB-induced atopic dermatitis model

Prakrati Garg, Aaliya Ali, Sewa Singh, Kanika Thakur, Kaisar Raza, Bigul Yogeshver Bhardwaj, Saurabh Kulshrestha, Poonam Negi

Gastroprotective effect of Arabincoside B isolated from Caralluma arabica against ethanol-induced gastric injury via modulating oxidative stress/SP/NK-1R/NF-κB loop

Dalia E. Ali, Othman S. S. Al-Hawshabi, Sarah A. Abd El-Aal, Eman Sheta, Sherihan Salaheldin Abdelhamid Ibrahim, Amira A. El-Gazar, Essam Abdel-Sattar, Ghada M. Ragab

Effect of N-Acetylcysteine on mortality in COVID-19 patients: A systematic review and meta-analysis of randomized controlled trials

Chia Siang Kow, Dinesh Sangarran Ramachandram, Syed Shahzad Hasan, Kaeshaelya Thiruchelvam

Concerning BPC-157, a natural pentadecapeptide, that acts as a cytoprotectant and is believed to protect the gastro-intestinal tract (GIT)

  • Open Access
  • Commentary

Michael Whitehouse

Jul 25
Issue: 7/2025
Sep 25
Issue: 9/2025

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