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Inflammopharmacology

Issue 6/2025

Content (40 Articles)

PDE4 inhibitors in psoriasis therapy: current insights and future directions

Amit Sharma, Niyati Pandoh, Keerti Dayal, Aditya Raj, Kirandeep Kaur, Navjot Kaur Sandhu, Vineet Kumar Rai, Shubham Thakur, Balak Das Kurmi

Paracetamol: the potential therapeutic pathways defining its clinical use

Hayder M. Al-Kuraishy, Ali I. Al-Gareeb, Ali K. Albuhadily, Eman M. Abd El-maksoud, Mustafa M. Shokr, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batiha

Protecting vascular health: the role of flavonoids during pregnancy complications in mitigating the risk of vascular dementia later in life

Ankita Sharma, Aman Jyoti, Prasad Rasane, Jyoti Singh

Exploring the efficacy of plant-based nutraceuticals in managing diabetic neuropathy

Samea Khan, Maria Markoulli, Amy T. Tsoi, Mark Willcox

Targeting the JAK/STAT3/SOCS signaling pathway in Alzheimer’s disease

Hayder M. Al-kuraishy, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Hebatallah M. Saad, Ali I. Al-Gareeb, Ali K. Albuhadily

Bioactive compound nanoparticles for Alzheimer's disease

Neha Kshirsagar, Ashwani Patil, Meghraj Suryawanshi

Role of mGluR7 in Alzheimer’s disease: pathophysiological insights and therapeutic approaches

Garry Hunjan, Khadga Raj Aran

Decoding the role of glucocorticoid-regulated kinase 1 in Alzheimer's disease: a promising path toward novel therapeutic strategies

Yukti Mittal, Pankaj Kumar, Kajal Joshi, Khadga Raj Aran

The therapeutic mechanisms of quercetin on inflammatory diseases: an update

  • Review

Jie Xu, Haikun Hu, Haixu Jiang, Qiuzhu Wei, Honglin Zhang, Qingyi Lu

Carica papaya in health and disease: a review of its bioactive compounds for treating various disease conditions, including anti-inflammatory and anti-arthritic activities

Md. Khokon Miah Akanda, A. H. M. Nazmul Hasan, Sanzia Mehjabin, G. M. Masud Parvez, Sabina Yasmin, Md. Sayeed Akhtar, Saistha Anjum, Sumel Ashique, Rokeya Sulatana, Mohammad Yousuf Ansari

Farnesol alleviates inflammatory responses and oxidative stress in Freund’s complete adjuvant induced arthritic rat model and associated risk factors of atherosclerosis

Isma Anwar, Ali Sharif, Mushtaq Ahmad, Maryam Shabbir, Bushra Akhtar

Amelioration of Freund’s adjuvant-induced polyarthritis by Diosmin-loaded nanoparticles in Wistar rats; a mechanistic study

Hamna Mehmood, Ammara Saleem, Muhammad Furqan Akhtar, Aisha Mobashar

N-Dimethyl chalcone facilitated augmentation of IL-10 and diminution of TNF-α, IL-1β, IL-6, NFκB, and COX-2 in FCA-induced arthritic rat model

Faiza Waseem, Ali Sharif, Maryam Shabbir, Bushra Akhtar, Syed Wadood Ali Shah, Shahnaz, Adeel Arshad, Ejaz Basheer, Muhammad Asif Hanif, Muhammad Ali

Nimesulide and sodium hyaluronate ameliorate the inflammatory process and pain severity in traumatic knee osteoarthritis

Wei Wang, Yao Du, Xiaohe Zhang

Cassia fistula fruit pulp extracts mitigate collagen-induced arthritis via regulation of oxidative stress and inflammation

Aashcharya U. Mishra, Sumati Sen, Mridula Sahu, Meenu Devi, Dewasya P. Singh, Aakriti Gupta, Abhishek K. Rai, Ratnasekhar Ch, Ashutosh K. Shukla, Dnyaneshwar U. Bawankule, Daya N. Mani

Dapagliflozin targets the crosstalk between apoptosis, autophagy, and Hedgehog signaling pathways through AMPK activation in the adjuvant-induced arthritic rat model

Aya A. El-Demerdash, Samar F. Darwish, Marwa O. El-Derany, Ebtehal El-Demerdash

Ipomoea carnea Jacq. ameliorates formalin-induced paw inflammation in rats through modulation of oxidative and inflammatory pathways

Shabab Nasir, Muhammad Usman, Humaira Gul, Malik Saadullah, Maryam Farrukh, Rida Siddique, Bushra Shaukat, Abdullah R. Alanzi, Ana Sanches Silva, Muhammad Ajmal Shah

Anti-arthritic potential and mechanistic insights of methanol extract of Rhamnus prinoides Engl. in complete Freund’s adjuvant-induced rats

James Kimani Kamau, Mathew Piero Ngugi, Joseph N. Ngeranwa

Phytochemical studies of Gerbera jamesonii and evaluation of anti-inflammatory potential in formaldehyde-induced arthritis in rats

Malik Saad Ullah, Ateeq Amjad, Zunera Chauhdary, Uzma Saleem, Naheed Akhtar

Phytofabricated Farsetia aegyptia-derived silver nanoparticles mediate antibacterial and wound-healing activities in diabetic foot infection rat model

Enas M. Ali, Peramaiyan Rajendran, Basem M. Abdallah

Phytochemical analysis of leaf extract of Piper nigrum and investigation of its biological activities

Pankaj Barman, Srija Hazarika, Kallol Roy, Ravindra K. Rawal, Rituraj Konwar

Full-spectrum Cannabis sativa extract enhances gut-peripheral organ integrity after experimental ischemic stroke

Solange de Souza Stork, Khiany Mathias, Fernanda Gava, Larissa Joaquim, David dos Santos, Anita Dal Bó Tiscoski, Sandra Bonfante, Yasmin Ribeiro Strickert, Richard Simon Machado, Helena Mafra Martins, Jéssica Schaefer Chaves, Jaqueline Generoso, Lucineia Gainski Danielski, Amanda Della Giustina, Rahisa Scussel, Rafael Bitencourt, Josiel Mileno Mack, Mariana Pereira de Souza Goldim, Ricardo Andrez Machado-de-Ávila, Tatiana Barichello, Franciane Bobinski, Fabricia Petronilho

Repurposing of high-dose N-acetylcysteine as anti-inflammatory, antioxidant and neuroprotective  agent  in moderate to severe traumatic brain injury patients: a randomized controlled trial

Alaa Refaat Gouda, Noha A El-Bassiouny, Ahmad Salahuddin, Emad Hamdy Hamouda, Amira B. Kassem

Voclosporin promotes neurological function recovery by inhibiting inflammation and maintaining blood–brain barrier integrity following rtPA reperfusion after MCAO in mice

Yangmin Zheng, Shubei Ma, Wei Sun, Feng Yan, Yumin Luo

The neuroprotective potential of Gerbera Jamesonii in a neuronal demyelination rat model through the modulation of interleukins, cyclooxygenase and tumor necrosis factor-α

Shazia Anwer Bukhari, Haleema Sadia, Zunera Chauhdary

Carnosol mitigates Ang II-stimulated vascular injury and oxidative stress by directly binding to FAK and inhibiting its activation

  • Original Article

Yucheng Jiang, Zhaozheng Zheng, JunYi Wang, Yingjie Liao, Zhihan Jia, Wante Lin, Diyun Xu, Jiong Wang, Gaojun Wu, Guang Liang, Bozhi Ye

Bioactive potential of Tripleurospermum inodorum with detailed insight into anti-inflammatory activity through in vitro, in vivo evaluations and network pharmacology

  • Original Article

Marija Ivanov, Aleksandra Popov Aleksandrov, Jelena Božunović, Maria Inês Dias, Ricardo C. Calhelha, Jelena Kulaš, Lillian Barros, Isabel C. F. R. Ferreira, Dejan Stojković

Evaluation of anti-inflammatory and anti-oxidant properties of Anacardium occidentale leaf

  • Original Article

Eleazar Chukwuemeka Anorue, Parker Elijah Joshua, Onyinyechi Chinwedu Asogwa

Naproxen and prednisolone reduced intestinal alteration and permeability and bacterial translocation in rat adjuvant-induced arthritis

Sophie Hecquet, Perle Totoson, Hélène Martin, Philippe Saas, Jean-Paul Pais-de-Barros, Maude Tournier, Clément Prati, Daniel Wendling, Céline Demougeot, Frank Verhoeven

Unveiling the neuroprotective potential of Jatropha humboldtiana leaves and its metabolic profiling by UPLC-MS/MS

Paul Alan Arkin Alvarado-García, Marilú Roxana Soto-Vásquez, Ricardo D. D. G. de Albuquerque, Fadia S. Youssef, Reem M. Diri, Mohamed L. Ashour

Camellia nitidissima Chi extract ameliorates dextran sulfate sodium-induced acute ulcerative colitis in mice by inhibiting TLR4/NF-κB-mediated inflammatory activation

Lirong Li, Rui Huang, Wenwen Li, Dengjie Yao, Beibei Zhang, Mengna Li, Shunan Luo, Yu Qin, Wenwen Zhang

Iota-carrageenan oligosaccharide ameliorates DSS-induced colitis in mice by mediating gut microbiota dysbiosis and modulating SCFAs-PI3K-AKT pathway

Meixian Xiang, Songtao Wu, Minxin Liu, Bin Zhang, Xiankun Xia, Wenjing Tan, Shijian Xiang

Chaperone-mediated autophagy, heat shock protein 70, and serotonin: novel targets of beta-hydroxybutyrate in HFFD/LPS-induced sporadic Alzheimer’s disease model

Reem A. Mohamed, Dalaal M. Abdallah, Hanan S. El-Abhar

Empagliflozin and memantine combination ameliorates cognitive impairment in scopolamine + heavy metal mixture-induced Alzheimer’s disease in rats: role of AMPK/mTOR, BDNF, BACE-1, neuroinflammation, and oxidative stress

Ebtsam S. Abdel-lah, Hoda S. Sherkawy, Wafaa H. Mohamed, Mariam A. Fawy, Asmaa A. Hasan, Asmaa A. Muhammed, Amira F. Taha, Abeer A. Tony, Nashwa Hamad, Marwa G. Gamea

Clinical study evaluating the efficacy and safety of Cilostazol as an adjuvant therapy to methotrexate on patients with rheumatoid arthritis

Samar M. Eldadamony, Sahar M. El-Haggar, Abdel Moaty A. Ali, Tarek M. Mostafa

Correction to: Anti-arthritic and immunomodulatory efficacy of Micromeria biflora Benth extract and its fractions in rats by restoring oxidative stress, metalloproteinases, pro-inflammatory and anti-inflammatory cytokines network

  • Correction

Fakhria A. Al-Joufi, Ambreen Malik Uttra, Sumera Qasim, Urooj Iqbal, Nabeela Tabassum Sial, Noura M. Alhumaid

Correction: Exploration of molecular interactions responsible for anti-inflammatory attributes of GI friendly micro-sized formulation of flurbiprofen and clove oil

Hafiz Muhammad Zubair, Mohamed Farouk Elsadek, Sajid Asghar, Khalid S. Al-Numair, Malik Saadullah, Shafqat Rasul Chaudhry, Thomas Efferth, Muhammad Asif

Correction: Vitamin D: a key player in COVID‑19 immunity and lessons from the pandemic to combat immune‑evasive variants

Hussein Sabit, Shaimaa Abdel-Ghany, Mahmoud S. Abdallah, Osama Abul-Maaty, Ahmed I. Khoder, Nabil A. Shoman, Mohamed Sameh Farrag, Pavel Martasek, Ayman M. Noreddin, Mahmoud Nazih

Correction: The impact of tocilizumab treatment on the severity of inflammation and survival rates in sepsis is significantly influence by the timing of administration

Taha Tavaci, Zekai Halici, Elif Cadirci, Mustafa Ozkaraca, Kamber Kasali

Retraction Note: Exploring the therapeutic potential of Anastatica hierochuntica essential oil in DSS-induced colitis

  • Retraction Note

Abdelrahim Alqudah, Esam Qnais, Omar Gammoh, Yousra Bseiso, Mohammed Wedyan, Mohammed Alqudah, Muna Oqal, Rawan Abudalo, Shtaywy S. Abdalla

May 25
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