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Inflammopharmacology

Issue 4/2025

Content (35 Articles)

Pharmacological modes of plant-derived compounds for targeting inflammation in rheumatoid arthritis: A comprehensive review on immunomodulatory perspective

Laiba Nazakat, Shaukat Ali, Muhammad Summer, Fakiha Nazakat, Shehzeen Noor, Anfah Riaz

Targeting mTOR with curcumin: therapeutic implications for complex diseases

  • Review

Danial Khayatan, Seyed Mehrad Razavi, Zahra Najafi Arab, Hadis Nasoori, Abtin Fouladi, Aytak Vahdat Khajeh Pasha, Alexandra E. Butler, Sercan Karav, Saeideh Momtaz, Amir Hossein Abdolghaffari, Amirhossein Sahebkar

Emerging treatments for dermatologic diseases in infants, children, and adolescents: a systematic review of clinical trials on biologics and small molecule inhibitors

Alireza Jafarzadeh, Elham Behrangi, Mina Khosravi, Saba Falakeh, Jasmine Khalilnejad Amiri, Azadeh Goodarzi

Therapeutic applications of natural products in the management of venous diseases: a comprehensive review

Rasha E. Mostafa, Dalia E. Ali, Riham A. El-Shiekh, Ahmed N. El-Alfy, Mohamed S. Abd El Hafeez, Ahmed M. Reda, Nesrin M. Fayek

Orientin: a comprehensive review of a promising bioactive flavonoid

  • Open Access
  • Review

Mohamed I. Fahmy, Mohamed A. Sadek, Kareem Abdou, Ahmed M. El-Dessouki, Riham A. El-Shiekh, Samar S. Khalaf

NLRP3 inflammasomes pathway: a key target for Metformin

Yasamin Hosseini, Amirhossein Niknejad, Ayeh Sabbagh Kashani, Mahsa Gholami, Mahtab Roustaie, Mohammad Mohammadi, Saeideh Momtaz, Stephen L. Atkin, Tannaz Jamialahmadi, Amir Hossein Abdolghaffari, Amirhossein Sahebkar

The efficacy, safety, and persistence of vedolizumab versus adalimumab in patients with inflammatory bowel disease: a systematic review and meta-analysis

Zhixin Chen, Huo Li, Zhongzhuan Li, Rong Ouyang, Shijiang Huang, Shufen Qin, Jing Qin, Jiean Huang

Ceramide: a central regulator in Alzheimer’s disease pathogenesis

Priyanka Choudhary, Shilpa Kumari, Kajal Bagri, Rahul Deshmukh

Interplay between PI3k/AKT signaling and caspase pathway in Alzheimer disease: mechanism and therapeutic implications

Vandana Bhatia, Vir Vikram, Anjali Chandel, Aditya Rattan

Diverse role of S100 calcium-binding protein B in alzheimer’s disease: pathological mechanisms and therapeutic implications

Sampriti Sarkar, Pratyush Porel, Sourabh Kosey, Khadga Raj Aran

Insulin resistance in Alzheimer's disease: signalling mechanisms and therapeutics strategies

Mini Dahiya, Monu Yadav, Chetan Goyal, Anil Kumar

Innovative nanocarriers in arthritis therapy: the role of herbal cubosomes

Kajal Chaudhary, Lubhan Singh, Pallavi Dinanath Rai

The association between glucocorticoids and long COVID

Yan Zhao, Guangting Zeng

Bacillus subtilis (NMCC-path-14) ameliorates acute phase of arthritis via modulating NF-κB and Nrf-2 signaling in mice model

Muhammad Usama Mazhar, Sadaf Naz, Tayyaba Zulfiqar, Jehan Zeb Khan, Fahim Hilal, Shakira Ghazanfar, Muhammad Khalid Tipu

Use quercetin for pulmonary fibrosis: a preclinical systematic review and meta-analysis

Xuanyu Wu, Xiang Xiao, Yuchen Su, Yuwei Zhang, Ganggang Li, Fei Wang, Quanyu Du, Han Yang

Therapeutic efficacy of zoledronic acid combined with calcium and calcitriol in the treatment of senile osteoporosis in elderly patients

Yi Zhang, Yuan Tian, Xiaojun Chen

Jasminum humile extract mitigates carrageenan-induced paw oedema in rats by modulating inflammatory and antioxidant signalling pathways

Mehreen Fatima, Lamya Ahmed Al-Keridis, Mohd Adnan, Nawaf Alshammari, Abdel Moneim Elhadi Sulieman, Muhammad Rashid Khan

Immunomodulatory properties of a methanolic extract of Ficus lyrata mitigate inflammation in Complete Freund’s Adjuvant-induced arthritis

Anam Iftikhar, Mohammad Saleem, Syed Atif Raza, Adrian Achuthan, Rodney Luwor, Taha Muhammad, Umair Majeed

Casticin reduces rosacea-related inflammation by inhibiting mast cell activation via Mas-related G protein-coupled receptor X2

Tao Jia, Yifan Xia, Mengyao Yi, Xinyue Zhang, Yi Zheng, Delu Che

Vanillic acid ameliorates collagen-induced arthritis by suppressing the inflammation response via inhibition of the MAPK and NF-κB signaling pathways

Yu Zhou, Pengfei Li, Zhongwen Zhi, Rong Chen, Chenghai Li, Chunbing Zhang

Nuclear receptor 4A1 inhibits chondrocyte inflammation and cartilage degeneration in osteoarthritis by inhibiting NF-κB signal pathway

Yawei Zhang, Hengheng Zheng, Baitong Li

Efficacy of Aster chinensis aerial parts metabolites in BALB/c mice model of Imiquimod-induced psoriasis skin inflammation

Mai S. Hendawy, Mona M. Hashem, Ahmed A. Zaki, Mostafa A. Rabie, Nesrine S. El Sayed, Riham Salah El Dine, Ali M. El-Halawany

Sodium hyaluronate and acupotomy bone decompression alleviates inflammatory responses in patients with knee osteoarthritis

Jia Wu, Qiong Tang, Xiaofei Tan

Treatment with cyclosporine attenuates the inflammatory process and severity of bisphosphonate-induced osteonecrosis of the jaws in rats

Camila Costa Dias, Caio Ferreira Freire Caetano, Gabriella Alves Julião Costa, Antônio Alexandre Coelho, José Vitor Mota Lemos, Dayrine Silveira de Paula, Juliana Paiva Marques Lima, Paulo Goberlânio de Barros Silva

Unravelling the prophylactic anti-inflammatory potential of Koenigia tortuosa through modulation of cytokine levels and inflammatory markers in LPS-induced localized inflammation in Wistar rat models

Ambreena Farooq, Mudasar Nabi, Khalid Bashir Dar, Syed Ishfa Andrabi, Nuzhat Khursheed, Farhat Jabeen, Showkat Ahmad Dar, Aijaz Hassan Ganie, Abdul Wajid Bhat, Showkat Ahmad Ganie

Unveiling the neuroprotective potential of Ipomoea carnea ethanol extract via the modulation of tau and β-secretase pathways in AlCl3-induced memory impairment in rats in relation to its phytochemical profiling

Walaa A. El-Kashak, Ahmed F. Essa, Mohamed F. Abdelhameed, Yasmine H. Ahmed, Asmaa S. Abd Elkarim, Mai M. Elghonemy, Bassant M. M. Ibrahim, Ahmed H. Gaara, Tahia K. Mohamed, Abdelsamed I. Elshamy

Kirenol ameliorates endotoxin-induced acute lung injury by inhibiting the ERK and JNK phosphorylation–mediated NFκB pathway in mice

Frank Cheau-Feng Lin, Shih-Pin Chen, Sheng-Chien Lin, Ching-Chi Tseng, Stella Chin-Shaw Tsai, Yu-Hsiang Kuan

Modulation of the cognitive impairment associated with Alzheimer’s disease by valproic acid: possible drug repurposing

Mirna Ezzat Sedrak Sorial, Ragwa Mansour Abdelghany, Nesrine Salah El Dine El Sayed

Gallic acid enhances memory, learning and reduces neuroinflammation in a rat model of scopolamine-induced cholinergic dysfunction

Mahbobe Alikhanzade, Maryam Khosravi, Mahmoud Hosseini, Arezoo Rajabian

The action of injectable nanodispersion of Bixa orellana (Chronic-in®) on arthritis in diabetic rats: pharmacological and histopathological studies

Lauana Gomes, Helison de Oliveira Carvalho, Gisele Rocha Lopes, Gabriel da Costa Furtado, Danna Emanuelle Santos Gonçalves, Nayara Nilcia Dias Colares, Adriana Maciel Ferreira, Crislany da Costa Furtado, Heitor Ribeiro da Silva, Abrahão Victor Tavares de L.T. dos Santos, Aline Lopes do Nascimento, Tamiris Marques Lage, Irma Danielle Rodrigues Pedro, Thiago Afonso Teixeira, José Carlos Tavares Carvalho

Neuroprotective efficacy of berberine and caffeine against rotenone‐induced neuroinflammatory and oxidative disturbances associated with Parkinson’s disease via inhibiting α-synuclein aggregation and boosting dopamine release

Tasnim S. Waheeb, Mohammad A. Abdulkader, Doaa A. Ghareeb, Mohamed E. Moustafa

Targeting TGF-β/VEGF/NF-κB inflammatory pathway using the Polyphenols of Echinacea purpurea (L.) Moench to enhance wound healing in a rat model

Marwa I. Ezzat, Mai M. Abdelhafez, Asmaa K. Al-Mokaddem, Shahira M. Ezzat

Curcumol attenuates hyperproliferation and inflammatory response in a psoriatic HaCaT keratinocyte model by inhibiting the PI3K-Akt pathway and ameliorates skin lesions and inflammatory status in psoriasis-like mice

Mutian Niu, Xiaolong Li, Mingzhao Li, Fangru Chen, Hui Cao, Qingbo Liu, Bin Liang, Guangyu Pan, Chengqin Liang, Jintao Gao

Therapeutic effect of formononetin in 6-OHDA induced Parkinson disease in rats

Tanvi Dayanand Pingale, Girdhari Lal Gupta

Editorial expression of concern: Chemomodulatory effect Melastoma Malabathricum Linn against chemically induced renal carcinogenesis rats via attenuation of inflammation, oxidative stress, and early markers of tumor expansion

  • Editorial Expression of Concern

Amita Verma, Prakash Chandra Bhatt, Gaurav kaithwas, Nikunj Sethi, Mohd Rashid, Yashwant Singh, Mahfoozur Rahman, Fahad Al-Abbasi, Firoz Anwar, Vikas Kumar