The leukotriene receptor antagonist montelukast reduces the risk for relapse in patients with ulcerative colitis in the steroid-tapering phase of therapy.
A comprehensive overview of the pathologies involving the second segment of the duodenum, highlighting the imaging findings that facilitate accurate diagnosis and effective management.
Patients with Crohn’s disease who do not initially respond to 12 weeks of induction therapy with risankizumab may benefit from extended treatment for up to a year.
Five men with ASUC that failed to respond to first-line corticosteroids received upadacitinib daily for 56 days. Short-term outcomes were favorable in terms of clinical response and clinical and corticosteroid-free remission.
A comprehensive overview of anemia in IBD—etiology, clinical features, outcomes, diagnosis, and management, including assessment of treatment response and the need for regular follow-up screening.
Five men with ASUC that failed to respond to first-line corticosteroids received upadacitinib daily for 56 days. Short-term outcomes were favorable in terms of clinical response and clinical and corticosteroid-free remission.
A 64-year-old man with a history of widely inactive Crohn's disease presented with IBS, chronic fatigue, and unexplained hip pain. What approach would you take to managing the patient?
A transgender woman with a sigmoid neovagina developed bloody diarrhea and neovaginal bleeding 10 years after sex reassignment surgery, highlighting the need for long-term vigilance.
Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease characterized by chronic inflammation and progressive fibrosis of the biliary tree, leading to significant liver function impairment over time. There is a strong association …
Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), is a chronic and debilitating gastrointestinal disorder caused by a complex interaction between genetic predisposition and microbial dysbiosis …
Parkinson’s disease (PD) is a neurodegenerative disorder primarily characterized by motor impairment, resulting from the accumulation of α-synuclein and neuronal cell death in the substantia nigra of the midbrain. Emerging evidence suggests that …
Children with Crohn’s disease (CD) may develop inflammation of the perianal and/or perineal regions in addition to intestinal involvement [ 1 ]. Manifestations of perianal CD include fistulas, abscesses, inflammatory masses, fissures, and skin tags …
Subcutaneous (SC) injection is the most frequently used method for administering biologics for several reasons, including ease of injection compared to intravenous or intramuscular administration, and potential for rapid onset of action [ 1 ].
Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease characterized by chronic inflammation and progressive fibrosis of the biliary tree, leading to significant liver function impairment over time. There is a strong association …
The activation of inflammasomes (NLRP3 and NLRP1) is central to the pathogenesis of inflammatory bowel disease (IBD). Here we examined the protective effects of a thioredoxin-mimetic peptide CB13 (TXM-CB13), known for its antioxidative stress and …
