Skip to main content
Key Specialties
Anesthesiology Cardiology Dermatology Diabetology Endocrinology Gastroenterology General Medicine Geriatrics Hematology Infectious Diseases Internal Medicine Nephrology Neurology Obstetrics and Gynecology Oncology Pediatrics Psychiatry Radiology Respiratory Medicine Rheumatology Surgery Urology
Congress Coverage
2024 ESMO Congress 2024 ERS Congress 2024 EASD Congress 2024 ESC Congress 2024 EAN Congress 2024 ASCO Annual Meeting 2024 ACC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote series | Spotlight on menopause

Menopause can have a significant impact on the body, with effects ranging beyond the endocrine and reproductive systems. Learn about the systemic effects of menopause, so you can help patients in your clinics through the transition.

Launching: Thursday 12th December 2024
ADVANCED SEARCH
Log in
Top
BMC Geriatrics
Published in:

Open Access 01-12-2024 | Systematic Review

Impact of multicomponent exercise and nutritional supplement interventions for improving physical frailty in community-dwelling older adults: a systematic review and meta-analysis

Authors: Wachiranun Sirikul, Nida Buawangpong, Kanokporn Pinyopornpanish, Penprapa Siviroj

Published in: BMC Geriatrics | Issue 1/2024

Login to get access

Abstract

Objective

To investigate the efficacy of both multicomponent exercise and nutritional interventions on frailty by conducting a systematic review and meta-analysis to examine changes in frailty incidence.

Design

A systematic review and meta-analysis.

Eligible criteria

The included studies were limited to original controlled trials focused on frailty interventions in older adults aged 65 years and over. The studies involved only participants with specific diseases, and those recovering from surgery or being hospitalized were excluded.

Information sources

A systematic search was performed on three databases: PUBMED, EMBASE, and Cumulative Index to Nursing and Allied Health, with the latest search in October 2024. Three authors independently extracted the data using a standardized data collection form. Relative risks were used as a summary measure. Pooled-effect estimates of each outcome were calculated by the random-effects meta-analysis.

Results

After searching three databases, 5327 records were identified. After removing duplicates and screening the titles and abstracts, 19 multicomponent exercise studies and 7 nutritional intervention studies were eligible. In a pooled analysis of 18 multicomponent exercise RCTs, including a total of 3457 older adults, the multicomponent exercises showed a clinically significant reduction in frailty risk by relative change 55% times (95% CI 45% to 67%, p value < 0.001). The subgroup analysis of combinations of macronutrients and micronutrients also demonstrated statistically significant decrease in frailty risk by relative change 28% times (95% CI 11% to 72%, p value = 0.008).

Conclusion

Multicomponent exercises can effectively improve physical frailty, regardless of the duration and types of the activities, whereas the efficacy of nutritional supplements remains unclear. Personalized multicomponent approaches that incorporate both exercises and nutritional supplements have promised to enhance effectiveness in reducing frailty, thus warranting further investigation.

Trial registration

The study was registered on 12 September 2022, under PROSPERO registration number CRD42022357357.
Appendix
Available only for authorised users
Literature
1.
Collard RM, Boter H, Schoevers RA, Oude Voshaar RC. Prevalence of frailty in community-dwelling older persons: a systematic review. J Am Geriatr Soc. 2012;60(8):1487–92.PubMedCrossRef
2.
Bandeen-Roche K, Seplaki CL, Huang J, Buta B, Kalyani RR, Varadhan R, Xue QL, Walston JD, Kasper JD. Frailty in Older Adults: A Nationally Representative Profile in the United States. J Gerontol A Biol Sci Med Sci. 2015;70(11):1427–34.PubMedPubMedCentralCrossRef
3.
Dent E, Morley JE, Cruz-Jentoft AJ, Woodhouse L, Rodríguez-Mañas L, Fried LP, Woo J, Aprahamian I, Sanford A, Lundy J, et al. Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management. J Nutr Health Aging. 2019;23(9):771–87.PubMedPubMedCentralCrossRef
4.
5.
6.
Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56(3):M146-156.PubMedCrossRef
7.
8.
Hubbard RE, Peel NM, Samanta M, Gray LC, Mitnitski A, Rockwood K. Frailty status at admission to hospital predicts multiple adverse outcomes. Age Ageing. 2017;46(5):801–6.PubMedCrossRef
9.
Travers J, Romero-Ortuno R, Bailey J, Cooney MT. Delaying and reversing frailty: a systematic review of primary care interventions. The British journal of general practice : the journal of the Royal College of General Practitioners. 2019;69(678):e61–9.PubMedCrossRef
10.
Puts MTE, Toubasi S, Andrew MK, Ashe MC, Ploeg J, Atkinson E, Ayala AP, Roy A, Rodríguez Monforte M, Bergman H, McGilton K. Interventions to prevent or reduce the level of frailty in community-dwelling older adults: a scoping review of the literature and international policies. Age Ageing. 2017;46(3):383–92.PubMedPubMedCentral
11.
Angulo J, El Assar M, Álvarez-Bustos A, Rodríguez-Mañas L. Physical activity and exercise: Strategies to manage frailty. Redox Biol. 2020;35: 101513.PubMedPubMedCentralCrossRef
12.
Sadjapong U, Yodkeeree S, Sungkarat S, Siviroj P. Multicomponent Exercise Program Reduces Frailty and Inflammatory Biomarkers and Improves Physical Performance in Community-Dwelling Older Adults: A Randomized Controlled Trial. Int J Environ Res Public Health. 2020;17(11):3760.PubMedPubMedCentralCrossRef
13.
Goisser S, Guyonnet S, Volkert D. The Role of Nutrition in Frailty: An Overview. J Frailty Aging. 2016;5(2):74–7.PubMed
14.
Khera S, Abbasi M, Dabravolskaj J, Sadowski CA, Yua H, Chevalier B. Appropriateness of Medications in Older Adults Living With Frailty: Impact of a Pharmacist-Led Structured Medication Review Process in Primary Care. J Prim Care Community Health. 2019;10:2150132719890227.PubMedPubMedCentralCrossRef
15.
Cheng MH, Chang SF. Frailty as a Risk Factor for Falls Among Community Dwelling People: Evidence From a Meta-Analysis. Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing. 2017;49(5):529–36.PubMedCrossRef
16.
Negm AM, Kennedy CC, Thabane L, Veroniki AA, Adachi JD, Richardson J, Cameron ID, Giangregorio A, Petropoulou M, Alsaad SM, et al. Management of Frailty: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials. J Am Med Dir Assoc. 2019;20(10):1190–8.PubMedCrossRef
17.
Sun X, Liu W, Gao Y, Qin L, Feng H, Tan H, Chen Q, Peng L, Wu IXY. Comparative effectiveness of non-pharmacological interventions for frailty: a systematic review and network meta-analysis. Age Ageing. 2023;52(2):afad004.CrossRef
18.
19.
Thomson KH, Rice S, Arisa O, Johnson E, Tanner L, Marshall C, Sotire T, Richmond C, O’Keefe H, Mohammed W, et al. Effectiveness and cost-effectiveness of oral nutritional supplements in frail older people who are malnourished or at risk of malnutrition: a systematic review and meta-analysis. The Lancet Healthy Longevity. 2022;3(10):e654–66.PubMedCrossRef
20.
Moraes MB, Avgerinou C, Fukushima FB, Vidal EIO. Nutritional interventions for the management of frailty in older adults: systematic review and meta-analysis of randomized clinical trials. Nutr Rev. 2021;79(8):889–913.PubMedCrossRef
21.
Han CY, Miller M, Yaxley A, Baldwin C, Woodman R, Sharma Y. Effectiveness of combined exercise and nutrition interventions in prefrail or frail older hospitalised patients: a systematic review and meta-analysis. BMJ Open. 2020;10(12): e040146.PubMedPubMedCentralCrossRef
22.
Huang CY, Mayer PK, Wu MY, Liu DH, Wu PC, Yen HR. The effect of Tai Chi in elderly individuals with sarcopenia and frailty: A systematic review and meta-analysis of randomized controlled trials. Ageing Res Rev. 2022;82: 101747.PubMedCrossRef
23.
Weng WH, Cheng YH, Yang TH, Lee SJ, Yang YR, Wang RY. Effects of strength exercises combined with other training on physical performance in frail older adults: A systematic review and meta-analysis. Arch Gerontol Geriatr. 2022;102: 104757.PubMedCrossRef
24.
Daryanti Saragih I, Yang YP, Saragih IS, Batubara SO, Lin CJ. Effects of resistance bands exercise for frail older adults: A systematic review and meta-analysis of randomised controlled studies. J Clin Nurs. 2022;31(1–2):43–61.PubMedCrossRef
25.
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372: n71.PubMedPubMedCentralCrossRef
26.
Tarazona-Santabalbina FJ, Gómez-Cabrera MC, Pérez-Ros P, Martínez-Arnau FM, Cabo H, Tsaparas K, Salvador-Pascual A, Rodriguez-Mañas L, Viña J. A Multicomponent Exercise Intervention that Reverses Frailty and Improves Cognition, Emotion, and Social Networking in the Community-Dwelling Frail Elderly: A Randomized Clinical Trial. J Am Med Dir Assoc. 2016;17(5):426–33.PubMedCrossRef
27.
Oliveira Gonçalves Id, Bandeira AN, Coelho-Júnior HJ, Silva Aguiar Sd, Minucci Camargo S, Yukio Asano R, Batista Júnior ML. Multicomponent Exercise on Physical Function, Cognition and Hemodynamic Parameters of Community-Dwelling Older Adults: A Quasi-Experimental Study. Int J Environ Res Public Health. 2019;16(12):2184. https://​doi.​org/​10.​3390/​ijerph16122184.
28.
Chodzko-Zajko WJ, Proctor DN, Fiatarone Singh MA, Minson CT, Nigg CR, Salem GJ, Skinner JS: American College of Sports Medicine position stand. Exercise and physical activity for older adults. Med Sci Sports Exerc 2009, 41(7):1510–1530.
29.
Sterne JAC, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I, Cates CJ, Cheng HY, Corbett MS, Eldridge SM, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366: l4898.
30.
Sterne JA, Hernán MA, Reeves BC, Savović J, Berkman ND, Viswanathan M, Henry D, Altman DG, Ansari MT, Boutron I, et al. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016;355: i4919.PubMedPubMedCentralCrossRef
31.
32.
33.
34.
Moreira NB, Rodacki ALF, Costa SN, Pitta A, Bento PCB. Perceptive-Cognitive and Physical Function in Prefrail Older Adults: Exergaming Versus Traditional Multicomponent Training. Rejuvenation Res. 2021;24(1):28–36.PubMedCrossRef
35.
Merchant RA, Tsoi CT, Tan WM, Lau W, Sandrasageran S, Arai H. Community-Based Peer-Led Intervention for Healthy Ageing and Evaluation of the “HAPPY” Program. J Nutr Health Aging. 2021;25(4):520–7.PubMedPubMedCentralCrossRef
36.
Garcia R, Costa SN, Garcia E, Bento PCB. Does Home-Based Exercise Improve the Physical Function of Prefrail Older Women? Rejuvenation Res. 2021;24(1):6–13.PubMedCrossRef
37.
Costa SN, Vieira ER, Bento PCB. Effects of Home- and Center-Based Exercise Programs on the Strength, Function, and Gait of Prefrail Older Women: A Randomized Control Trial. J Aging Phys Act. 2020;28(1):122–30.PubMedCrossRef
38.
39.
Luger E, Dorner TE, Haider S, Kapan A, Lackinger C, Schindler K. Effects of a Home-Based and Volunteer-Administered Physical Training, Nutritional, and Social Support Program on Malnutrition and Frailty in Older Persons: A Randomized Controlled Trial. J Am Med Dir Assoc. 2016;17(7):671.e679-671.e616.CrossRef
40.
Gené Huguet L, Navarro González M, Kostov B, Ortega Carmona M, Colungo Francia C, Carpallo Nieto M, Hervás Docón A, Vilarrasa Sauquet R, García Prado R, Sisó-Almirall A. Pre Frail 80: Multifactorial Intervention to Prevent Progression of Pre-Frailty to Frailty in the Elderly. J Nutr Health Aging. 2018;22(10):1266–74.PubMedCrossRef
41.
Courel-Ibáñez J, Buendía-Romero Á, Pallarés JG, García-Conesa S, Martínez-Cava A, Izquierdo M. Impact of Tailored Multicomponent Exercise for Preventing Weakness and Falls on Nursing Home Residents’ Functional Capacity. J Am Med Dir Assoc. 2022;23(1):98-104.e103.PubMedCrossRef
42.
Carnavale BF, da Silva Santos VR, Farche ACS, Rossi PG, Fiogbé E, de Souza Buto MS, de Vassimon-Barroso V, de Medeiros Takahashi AC. Effects of a multicomponent training and detraining on frailty status, physical activity level, sedentary behavior patterns and physical performance of pre-frail older adults: a randomized controlled trial. Eur Geriatr Med. 2024. https://​doi.​org/​10.​1007/​s41999-024-01052-4.
43.
Cesari M, Vellas B, Hsu FC, Newman AB, Doss H, King AC, Manini TM, Church T, Gill TM, Miller ME, Pahor M. A physical activity intervention to treat the frailty syndrome in older persons-results from the LIFE-P study. J Gerontol A Biol Sci Med Sci. 2015;70(2):216–22.PubMedCrossRef
44.
Ferreira CB, Teixeira PDS. Alves Dos Santos G, Dantas Maya AT, Americano do Brasil P, Souza VC, Córdova C, Ferreira AP, Lima RM, Nóbrega OT: Effects of a 12-Week Exercise Training Program on Physical Function in Institutionalized Frail Elderly. J Aging Res. 2018;2018:7218102.PubMedPubMedCentralCrossRef
45.
Arrieta H, Rezola-Pardo C, Gil SM, Virgala J, Iturburu M, Antón I, González-Templado V, Irazusta J, Rodriguez-Larrad A. Effects of Multicomponent Exercise on Frailty in Long-Term Nursing Homes: A Randomized Controlled Trial. J Am Geriatr Soc. 2019;67(6):1145–51.PubMedCrossRef
46.
Serra-Prat M, Sist X, Domenich R, Jurado L, Saiz A, Roces A, Palomera E, Tarradelles M, Papiol M. Effectiveness of an intervention to prevent frailty in pre-frail community-dwelling older people consulting in primary care: a randomised controlled trial. Age Ageing. 2017;46(3):401–7.PubMed
47.
Seesen M, Semmarath W, Yodkeeree S, Sapbamrer R, Ayood P, Malasao R, Ongprasert K, Chittrakul J, Siviroj P, Limtrakul P. Combined Black Rice Germ, Bran Supplement and Exercise Intervention Modulate Aging Biomarkers and Improve Physical Performance and Lower-Body Muscle Strength Parameters in Aging Population. Int J Environ Res Public Health. 2020;17(8):2931. https://​doi.​org/​10.​3390/​ijerph17082931.CrossRefPubMedPubMedCentral
48.
Chiu TY, Yu HW. Associations of multicomponent exercise and aspects of physical performance with frailty trajectory in older adults. BMC Geriatr. 2022;22(1):559.PubMedPubMedCentralCrossRef
49.
García-Vigara A, Fernandez-Garrido J, Carbonell-Asíns JA, Sánchez-Sánchez ML, Monllor-Tormos A, García-Pérez MA, Tarín JJ, Cano A. Physical activity to reduce the burden of frailty after menopause: effectiveness and adherence rate of a resource saving exercise plan. Menopause. 2024;31(7):634–40.PubMedCrossRef
50.
Biesek S, Vojciechowski AS, Filho JM, Menezes Ferreira ACRd, Borba VZC, Rabito EI, Gomes ARS. Effects of Exergames and Protein Supplementation on Body Composition and Musculoskeletal Function of Prefrail Community-Dwelling Older Women: A Randomized, Controlled Clinical Trial. Int J Environ Res Public Health. 2021;18(17):9324. https://​doi.​org/​10.​3390/​ijerph18179324.
51.
Guerville F, de Souto BP, Giudici KV, Rolland Y, Vellas B. Association of 3-Year Multidomain Intervention and Omega-3 Supplementation with Frailty Incidence. J Am Geriatr Soc. 2019;67(8):1700–6.PubMedCrossRef
52.
Na W, Kim J, Kim H, Lee Y, Jeong B, Lee SP, Sohn C. Evaluation of Oral Nutritional Supplementation in the Management of Frailty among the Elderly at Facilities of Community Care for the Elderly. Clin Nutr Res. 2021;10(1):24–35.PubMedPubMedCentralCrossRef
53.
Barrachina-Igual J, Martínez-Arnau FM, Pérez-Ros P, Flor-Rufino C, Sanz-Requena R, Pablos A. Effectiveness of the PROMUFRA program in pre-frail, community-dwelling older people: A randomized controlled trial. Geriatr Nurs. 2021;42(2):582–91.PubMedCrossRef
54.
Casas-Herrero Á, Sáez de Asteasu ML, Antón-Rodrigo I, Sánchez-Sánchez JL, Montero-Odasso M, Marín-Epelde I, Ramón-Espinoza F, Zambom-Ferraresi F, Petidier-Torregrosa R, Elexpuru-Estomba J et al: Effects of Vivifrail multicomponent intervention on functional capacity: a multicentre, randomized controlled trial. J Cachexia Sarcopenia Muscle 2022, 13(2):884–893.
55.
Chan DD, Tsou HH, Chang CB, Yang RS, Tsauo JY, Chen CY, Hsiao CF, Hsu YT, Chen CH, Chang SF, et al. Integrated care for geriatric frailty and sarcopenia: a randomized control trial. J Cachexia Sarcopenia Muscle. 2017;8(1):78–88.PubMedCrossRef
56.
Liao YY, Chen IH, Wang RY. Effects of Kinect-based exergaming on frailty status and physical performance in prefrail and frail elderly: A randomized controlled trial. Sci Rep. 2019;9(1):9353.PubMedPubMedCentralCrossRef
57.
Liu Z, Hsu FC, Trombetti A, King AC, Liu CK, Manini TM, Fielding RA, Pahor M, Newman AB, Kritchevsky S, Gill TM. Effect of 24-month physical activity on cognitive frailty and the role of inflammation: the LIFE randomized clinical trial. BMC Med. 2018;16(1):185.PubMedPubMedCentralCrossRef
58.
Cameron ID, Fairhall N, Langron C, Lockwood K, Monaghan N, Aggar C, Sherrington C, Lord SR, Kurrle SE. A multifactorial interdisciplinary intervention reduces frailty in older people: randomized trial. BMC Med. 2013;11:65.PubMedPubMedCentralCrossRef
59.
Seino S, Nishi M, Murayama H, Narita M, Yokoyama Y, Nofuji Y, Taniguchi Y, Amano H, Kitamura A, Shinkai S. Effects of a multifactorial intervention comprising resistance exercise, nutritional and psychosocial programs on frailty and functional health in community-dwelling older adults: A randomized, controlled, cross-over trial. Geriatr Gerontol Int. 2017;17(11):2034–45.PubMedCrossRef
60.
Ng TP, Feng L, Nyunt MS, Feng L, Niti M, Tan BY, Chan G, Khoo SA, Chan SM, Yap P, Yap KB. Nutritional, Physical, Cognitive, and Combination Interventions and Frailty Reversal Among Older Adults: A Randomized Controlled Trial. Am J Med. 2015;128(11):1225-1236.e1221.PubMedCrossRef
61.
Badrasawi M, Shahar S, Zahara AM, Nor Fadilah R, Singh DK. Efficacy of L-carnitine supplementation on frailty status and its biomarkers, nutritional status, and physical and cognitive function among prefrail older adults: a double-blind, randomized, placebo-controlled clinical trial. Clin Interv Aging. 2016;11:1675–86.PubMedPubMedCentralCrossRef
62.
Kim H, Suzuki T, Kim M, Kojima N, Ota N, Shimotoyodome A, Hase T, Hosoi E, Yoshida H. Effects of exercise and milk fat globule membrane (MFGM) supplementation on body composition, physical function, and hematological parameters in community-dwelling frail Japanese women: a randomized double blind, placebo-controlled, follow-up trial. PLoS ONE. 2015;10(2): e0116256.PubMedPubMedCentralCrossRef
63.
Kara M, Kaymak B, Ata AM, Özkal Ö, Kara Ö, Baki A, Şengül Ayçiçek G, Topuz S, Karahan S, Soylu AR, et al. STAR-Sonographic Thigh Adjustment Ratio: A Golden Formula for the Diagnosis of Sarcopenia. Am J Phys Med Rehabil. 2020;99(10):902–8.PubMedCrossRef
64.
Jones CJ, Rikli RE, Beam WC. A 30-s chair-stand test as a measure of lower body strength in community-residing older adults. Res Q Exerc Sport. 1999;70(2):113–9.PubMedCrossRef
65.
Khant N, Dani VB, Patel P, Rathod R. Establishing the reference value for “timed up-and-go” test in healthy adults of Gujarat. India J Educ Health Promot. 2018;7:62.PubMedCrossRef
66.
Dent E, Lien C, Lim WS, Wong WC, Wong CH, Ng TP, Woo J, Dong B, de la Vega S, Hua Poi PJ, et al. The Asia-Pacific Clinical Practice Guidelines for the Management of Frailty. J Am Med Dir Assoc. 2017;18(7):564–75.PubMedCrossRef
67.
68.
69.
Khor PY, Vearing RM, Charlton KE. The effectiveness of nutrition interventions in improving frailty and its associated constructs related to malnutrition and functional decline among community-dwelling older adults: A systematic review. J Hum Nutr Diet. 2022;35(3):566–82.PubMedCrossRef
70.
Golder S, Loke YK, Wright K, Norman G: Reporting of Adverse Events in Published and Unpublished Studies of Health Care Interventions: A Systematic Review. PLoS medicine 2016, 13(9):e1002127.
71.
Page MJ, McKenzie JE, Kirkham J, Dwan K, Kramer S, Green S, Forbes A: Bias due to selective inclusion and reporting of outcomes and analyses in systematic reviews of randomised trials of healthcare interventions. The Cochrane database of systematic reviews 2014, 2014(10):Mr000035.
72.
Cruz-Jentoft AJ, Sayer AA. Sarcopenia. The Lancet. 2019;393(10191):2636–46.CrossRef
73.
Negm AM, Kennedy CC, Thabane L, Veroniki A-A, Adachi JD, Richardson J, Cameron ID, Giangregorio A, Papaioannou A. Management of frailty: a protocol of a network meta-analysis of randomized controlled trials. Syst Rev. 2017;6(1):130.PubMedPubMedCentralCrossRef
Metadata
Title
Impact of multicomponent exercise and nutritional supplement interventions for improving physical frailty in community-dwelling older adults: a systematic review and meta-analysis
Authors
Wachiranun Sirikul
Nida Buawangpong
Kanokporn Pinyopornpanish
Penprapa Siviroj
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Geriatrics / Issue 1/2024
Electronic ISSN: 1471-2318
DOI
https://doi.org/10.1186/s12877-024-05551-8

Other articles of this Issue 1/2024

Inflammatory markers and frailty in home-dwelling elderly, a cross-sectional study

  • Open Access
  • Research

Development of the assessment standards of the International Classification of Functioning, Disability, and Health (ICF) Geriatric Core Set through a modified Delphi method

  • Open Access
  • Research

Effects of pericapsular nerve group block on early postoperative cognitive function in older people undergoing hip arthroplasty: a randomized controlled clinical trial

Risk factors of different mortality periods in older patients with end-stage renal disease undergoing urgent-start peritoneal dialysis: a retrospective observational study

Construction and verification of the prediction model for risk of sleep disturbance in elderly patients with hypertension: a cross-sectional survey based on NHANES database from 2005 to 2018

Experiences of Boosting Inpatient Exercise After HipFracture Surgery Using An Alternative Workforce - A Qualitative Study

  • Open Access
  • Research

Keynote series | Spotlight on menopause

Menopause can have a significant impact on the body, with effects ranging beyond the endocrine and reproductive systems. Learn about the broader systemic effects of menopause, so you can help patients in your clinics through the transition.

Launching: Thursday 12th December 2024
 

Prof. Martha Hickey
Dr. Claudia Barth
Dr. Samar El Khoudary
Developed by: Springer Medicine
Register your interest now

Keynote webinar | Spotlight on adolescent vaping

  • Live
  • Webinar | 29-01-2025 | 18:00 (CET)

Growing numbers of young people are using e-cigarettes, despite warnings of respiratory effects and addiction. How can doctors tackle the epidemic, and what health effects should you prepare to manage in your clinics?

Watch it live: Wednesday 29th January, 18:00-19:30 CET
 

Prof. Ann McNeill
Dr. Debbie Robson
Benji Horwell
Developed by: Springer Medicine
Join the webinar

Keynote webinar | Spotlight on modern management of frailty

Frailty has a significant impact on health and wellbeing, especially in older adults. Our experts explain the factors that contribute to the development of frailty and how you can manage the condition and reduce the risk of disability, dependency, and mortality in your patients.

Prof. Alfonso Cruz-Jentoft
Prof. Barbara C. van Munster
Prof. Mirko Petrovic
Developed by: Springer Medicine
Watch now

A quick guide to ECGs

Improve your ECG interpretation skills with this comprehensive, rapid, interactive course. Expert advice provides detailed feedback as you work through 50 ECGs covering the most common cardiac presentations to ensure your practice stays up to date. 

PD Dr. Carsten W. Israel
Developed by: Springer Medizin
Start the cases

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine
Read more
Image Credits