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Child's Nervous System

Impact of choroid plexus coagulation on the success of endoscopic third ventriculostomy in children with hydrocephalus: a single-center retrospective observational cohort study

Published in:
Authors
Artur Henrique Galvao Bruno da Cunha
Marcelo Moraes Valença
Pedro Lucas Negromonte Guerra
Inaê Carolline Silveira da Silva
Published in
Child's Nervous System | Issue 1/2025

Abstract

Introduction

Hydrocephalus is a common condition in childhood, often treated with ventriculoperitoneal shunts (VPS). Endoscopic third ventriculostomy (ETV) has emerged as an effective alternative, and the addition of choroid plexus coagulation (CPC) is believed to enhance its success, particularly in children under 6 months.

Methods

In this observational study, a retrospective analysis was conducted on 167 pediatric patients who underwent ETV, with and without CPC, at the Hospital da Restauração in Pernambuco. The primary outcome was to evaluate the success rates of ETV and ETV + CPC at immediate postoperative or outcome at discharge and 6-month follow-up. Statistical analyses, including chi-square, univariate, and multivariate logistic regression, were employed to assess correlations between dependent and independent variables.

Results

ETV + CPC showed a significantly higher success rate in the immediate postoperative period (91%) compared to ETV alone (75%) (p = 0.007). After 6 months, success rates were similar for both groups (67% for ETV + CPC and 66% for ETV), with no significant difference (p = 0.855). Univariate and multivariate analyses revealed that the type of surgery (ETV + CPC vs. ETV) was a significant predictor of immediate postoperative success (OR 2.81, 95%CI 1.18–6.72, p = 0.020). Age and sex did not correlate significantly with surgical outcomes.

Conclusion

The addition of CPC to ETV significantly enhances immediate postoperative success in young children with hydrocephalus. Although long-term outcomes equalized, these findings suggest that CPC can be a valuable adjunct in optimizing short-term results.
Title
Impact of choroid plexus coagulation on the success of endoscopic third ventriculostomy in children with hydrocephalus: a single-center retrospective observational cohort study
Authors
Artur Henrique Galvao Bruno da Cunha
Marcelo Moraes Valença
Pedro Lucas Negromonte Guerra
Inaê Carolline Silveira da Silva
Publication date
01-12-2025
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 1/2025
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-025-06755-y
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