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AIDS Research and Therapy
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Open Access 01-12-2024 | Human Immunodeficiency Virus | Case Report

Ixekizumab: an alternative for HIV-positive psoriasis patients

Authors: Fanghua Liu, Zhou Liu, Rongming Yang, Dandan Huang, Yongzhi Han

Published in: AIDS Research and Therapy | Issue 1/2024

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Abstract

Psoriasis is a recurrent and protracted inflammatory disease. Generalized erythema, plaques, and silvery scales on the surface mainly characterize its skin lesions. Biologics bring new hope to psoriasis patients. However, HIV infection is a major concern before receiving biologics. Here, we present a case of the efficacy and safety of Ixekizumab, an interleukin 17 inhibitor, in the treatment of psoriasis patients living with HIV (PPLHIV).
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Literature
1.
Alpalhão M, Borges-Costa J, Filipe P. Psoriasis in HIV infection: an update. Int J STD AIDS. 2019;30(6):596–604.CrossRefPubMed
2.
Ceccarelli M, et al. HIV-associated psoriasis: epidemiology, pathogenesis, and management. Dermatol Ther. 2019;32(2): e12806.CrossRefPubMed
3.
Kaushik SB, Lebwohl MG. Psoriasis: which therapy for which patient: Focus on special populations and chronic infections. J Am Acad Dermatol. 2019;80(1):43–53.CrossRefPubMed
4.
Smith CH, et al. British Association of Dermatologists guidelines for biologic therapy for psoriasis 2017. Br J Dermatol. 2017;177(3):628–36.CrossRefPubMed
5.
Xu, J., et al., The impact of psoriasis biologic therapy on HIV viral load and CD4(+) cell counts in HIV-positive individuals: A real-world cohort study. J Eur Acad Dermatol Venereol, 2023.
6.
Morar N, et al. HIV-associated psoriasis: pathogenesis, clinical features, and management. Lancet Infect Dis. 2010;10(7):470–8.CrossRefPubMed
7.
Myers B, et al. Biologic treatment of 4 HIV-positive patients: a case series and literature review. J Psoriasis Psoriatic Arthritis. 2021;6(1):19–26.CrossRefPubMed
8.
Pangilinan MCG, Sermswan P, Asawanonda P. Use of anti-IL-17 monoclonal antibodies in HIV patients with erythrodermic psoriasis. Case Rep Dermatol. 2020;12(2):132–7.CrossRefPubMedPubMedCentral
9.
Qian F, et al. Use of ixekizumab in an HIV-positive patient with psoriatic arthritis. Int J STD AIDS. 2022;33(5):519–21.CrossRefPubMed
10.
Menter A, et al. Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with biologics. J Am Acad Dermatol. 2019;80(4):1029–72.CrossRefPubMed
11.
Sood, S., et al., Use of biologic treatment in psoriasis patients with HIV: A systematic review. J Am Acad Dermatol, 2024.
12.
Penso L, et al. Association between biologics use and risk of serious infection in patients with psoriasis. JAMA Dermatol. 2021;157(9):1056–65.CrossRefPubMed
13.
Li L, et al. Reactivation rates of hepatitis B or C or HIV in patients with psoriasis using biological therapies: a systematic review and meta-analysis. Clin Exp Med. 2023;23(3):701–15.CrossRefPubMed
Metadata
Title
Ixekizumab: an alternative for HIV-positive psoriasis patients
Authors
Fanghua Liu
Zhou Liu
Rongming Yang
Dandan Huang
Yongzhi Han
Publication date
01-12-2024
Publisher
BioMed Central
Published in
AIDS Research and Therapy / Issue 1/2024
Electronic ISSN: 1742-6405
DOI
https://doi.org/10.1186/s12981-024-00675-8

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