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AIDS and Behavior

04-09-2024 | Human Immunodeficiency Virus | Substantive Review

Identifying Effective Strategies for Improving Engagement in HIV Prevention and Care Among Transgender Persons in the United States: A Systematic Review

Authors: Nicole Crepaz, Olivia Peters, Darrel H. Higa, Mary M. Mullins, Charles B. Collins

Published in: AIDS and Behavior

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Abstract

This systematic review synthesized published literature (2000 – 2023) to identify HIV interventions specifically designed for transgender persons in the United States (PROSPERO registration number: CRD42021256460). The review also summarized strategies for improving outcomes related to the four pillars of the Ending the HIV Epidemic (EHE) initiative in the United States: Diagnose, Treat, Prevent, and Respond. A comprehensive search was conducted using the Centers for Disease Control and Prevention’s HIV Prevention Research Synthesis Project database, which included over 120,000 citations from routine systematic searches in CINAHL, EMBASE, Global Health, MEDLINE, PsycInfo, and Sociological Abstracts. Of 23 interventions that met inclusion criteria, 94% focused on transgender women of color and 22% focused on young transgender persons aged 15–29 years old. Most interventions focused on Treat or Prevent, few focused on Diagnosis, and none focused on Respond. Twenty interventions (87%) showed improvement in at least one EHE related outcome and a quarter of these effective interventions were tested with randomized controlled trials. Common strategies observed in effective interventions include the following: engaging the community in intervention development; pilot-testing with the focus population to ensure appropriateness and acceptability; addressing social determinants of health (e.g. stigma, discrimination, violence) through empowerment and gender-affirming approaches; increasing access to care, prevention, and services through co-location and one-stop shop models; and utilizing peer-led counseling, education, support, and navigation. Continuous effort is needed in addressing gaps, including more research for transgender men and rural settings and for how best to adopt and adapt best practices for subgroups of transgender population.
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Literature
1.
Becasen JS, Denard CL, Mullins MM, Higa DH, Sipe TA. Estimating the prevalence of HIV and sexual behaviors among the US transgender population: a systematic review and meta-analysis, 2006–2017. Am J Public Health. 2019;109(1):e1–8.CrossRefPubMedPubMedCentral
2.
Goldhammer H, Marc LG, Chavis NS, et al. Interventions for addressing trauma among people with HIV: a narrative review. AIDS Care. 2022;34(4):505–14.CrossRefPubMed
3.
Lesko CR, Edwards JK, Hanna DB, et al. Longitudinal HIV care outcomes by gender identity in the United States. AIDS. 2022;36(13):1841–9.CrossRefPubMed
4.
Rosengren AL, Lelutiu-Weinberger C, Woodhouse EW, Sandanapitchai P, Hightow-Weidman LB. A scoping review of HIV pre-exposure prophylaxis stigma and implications for stigma-reduction interventions for men and transwomen who have sex with men. AIDS Behav. 2021;25(7):2054–70.CrossRefPubMedPubMedCentral
5.
Stutterheim SE, van Dijk M, Wang H, Jonas KJ. The worldwide burden of HIV in transgender individuals: an updated systematic review and meta-analysis. PLoS ONE. 2021;16(12): e0260063.CrossRefPubMedPubMedCentral
6.
Wirtz AL, Humes E, Althoff KN, et al. HIV incidence and mortality in transgender women in the eastern and southern USA: a multisite cohort study. Lancet HIV. 2023;10(5):e308–19.CrossRefPubMedPubMedCentral
7.
8.
9.
10.
Poteat T, Malik M, Scheim A, Elliott A. HIV prevention among transgender populations: knowledge gaps and evidence for action. Curr HIV/AIDS Rep. 2017;14(4):141–52.CrossRefPubMedPubMedCentral
11.
Poteat T, Simmons A. Intersectional structural stigma, community priorities, and opportunities for transgender health equity: findings from TRANSforming the Carolinas. J Law Med Ethics. 2022;50(3):443–55.CrossRefPubMedPubMedCentral
12.
Poteat T, Wirtz AL, Reisner S. Strategies for engaging transgender populations in HIV prevention and care. Curr Opin HIV AIDS. 2019;14(5):393–400.CrossRefPubMed
13.
Poteat TC, Malik M, Beyrer C. Epidemiology of HIV, sexually transmitted infections, viral hepatitis, and tuberculosis among incarcerated transgender people: a case of limited data. Epidemiol Rev. 2018;40(1):27–39.CrossRefPubMedPubMedCentral
14.
Moher D, Shamseer L, Clarke M, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev. 2015;4(1):1.CrossRefPubMedPubMedCentral
15.
Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. PLoS Med. 2021;18(3): e1003583.CrossRefPubMedPubMedCentral
16.
Stephenson R, Todd K, Kahle E, et al. Project Moxie: results of a feasibility study of a telehealth intervention to increase HIV testing among binary and nonbinary transgender youth. AIDS Behav. 2020;24(5):1517–30.CrossRefPubMedPubMedCentral
17.
Sevelius JM, Dilworth SE, Reback CJ, et al. Randomized controlled trial of healthy divas: a gender-affirming, peer-delivered intervention to improve HIV care engagement among transgender women living with HIV. J Acquir Immune Defic Syndr. 2022;90(5):508–16.CrossRefPubMedPubMedCentral
18.
Reback CJ, Fletcher JB, Kisler KA. Text messaging improves HIV care continuum outcomes among young adult trans women living with HIV: text me, Girl! AIDS Behav. 2021;25(9):3011–23.CrossRefPubMedPubMedCentral
19.
Eastwood EA, Nace AJ, Hirshfield S, Birnbaum JM. Young transgender women of color: homelessness, poverty, childhood sexual abuse and implications for HIV care. AIDS Behav. 2021;25(Suppl 1):96–106.CrossRefPubMed
20.
Rebchook GM, Chakravarty D, Xavier JM, et al. An evaluation of nine culturally tailored interventions designed to enhance engagement in HIV care among transgender women of colour in the United States. J Int AIDS Soc. 2022;25(Suppl 5): e25991.CrossRefPubMedPubMedCentral
21.
Galvan FH, Chen YT, Contreras R, O’Connell B. Violence inflicted on Latina transgender women living with HIV: rates and associated factors by perpetrator type. AIDS Behav. 2021;25(Suppl 1):116–26.CrossRefPubMed
22.
Hirshfield S, Contreras J, Luebe RQ, et al. Engagement in HIV care among New York City transgender women of color: findings from the peer-led, TWEET Intervention, a SPNS trans women of color initiative. AIDS Behav. 2021;25(Suppl 1):20–30.CrossRefPubMedPubMedCentral
23.
Kuhns LM, Hotton AL, Perloff J, et al. Evaluation of translife care: an intervention to address social determinants of engagement in HIV care among transgender women of color. AIDS Behav. 2021;25(Suppl 1):13–9.CrossRefPubMed
24.
Nemoto T, Iwamoto M, Suico S, Stanislaus V, Piroth K. Sociocultural contexts of access to HIV primary care and participant experience with an intervention project: african american transgender women living with HIV in alameda county. California AIDS Behav. 2021;25(Suppl 1):84–95.CrossRefPubMed
25.
Reback CJ, Kisler KA, Fletcher JB. A novel adaptation of peer health navigation and contingency management for advancement along the HIV care continuum among transgender women of color. AIDS Behav. 2021;25(Suppl 1):40–51.CrossRefPubMedPubMedCentral
26.
Swartz JA, Ducheny K, Holloway T, Stokes L, Willis S, Kuhns LM. A latent class analysis of chronic health conditions among HIV-positive transgender women of color. AIDS Behav. 2021;25(Suppl 1):52–63.CrossRefPubMed
27.
Wilson EC, Turner C, Arayasirikul S, et al. HIV care engagement among trans women of color in san francisco bay area demonstration projects: findings from the brandy martell project and transaccess. AIDS Behav. 2021;25(Suppl 1):31–9.CrossRefPubMed
28.
Bockting WO, Robinson BE, Forberg J, Scheltema K. Evaluation of a sexual health approach to reducing HIV/STD risk in the transgender community. AIDS Care. 2005;17(3):289–303.CrossRefPubMed
29.
Collier KL, Colarossi LG, Hazel DS, Watson K, Wyatt GE. Healing our women for transgender women: adaptation, acceptability, and pilot testing. AIDS Educ Prev. 2015;27(5):418–31.CrossRefPubMed
30.
Garofalo R, Johnson AK, Kuhns LM, Cotten C, Joseph H, Margolis A. Life skills: evaluation of a theory-driven behavioral HIV prevention intervention for young transgender women. J Urban Health. 2012;89(3):419–31.CrossRefPubMedPubMedCentral
31.
Garofalo R, Kuhns LM, Reisner SL, Biello K, Mimiaga MJ. Efficacy of an empowerment-based, group-delivered HIV prevention intervention for young transgender women: the project LifeSkills randomized clinical trial. JAMA Pediatr. 2018;172(10):916–23.CrossRefPubMedPubMedCentral
32.
Nemoto T, Operario D, Keatley J, Nguyen H, Sugano E. Promoting health for transgender women: transgender resources and neighborhood space (TRANS) program in San Francisco. Am J Public Health. 2005;95(3):382–4.CrossRefPubMedPubMedCentral
33.
Operario D, Gamarel KE, Iwamoto M, et al. Couples-focused prevention program to reduce HIV risk among transgender women and their primary male partners: feasibility and promise of the couples HIV intervention program. AIDS Behav. 2017;21(8):2452–63.CrossRefPubMedPubMedCentral
34.
Reback CJ, Clark K, Fletcher JB. Trans action: a homegrown, theory-based, HIV risk reduction intervention for transgender women experiencing multiple health disparities. Sex Res Social Policy. 2019;16(4):408–18.CrossRefPubMed
35.
Reisner SL, Hughto JM, Pardee DJ, Kuhns L, Garofalo R, Mimiaga MJ. LifeSkills for Men (LS4M): pilot evaluation of a gender-affirmative HIV and STI prevention intervention for young adult transgender men who have sex with men. J Urban Health. 2016;93(1):189–205.CrossRefPubMedPubMedCentral
36.
Taylor RD, Bimbi DS, Joseph HA, Margolis AD, Parsons JT. Girlfriends: evaluation of an HIV-risk reduction intervention for adult transgender women. AIDS Educ Prev. 2011;23(5):469–78.CrossRefPubMed
37.
Rhodes SD, Alonzo J, Mann-Jackson L, et al. Preexposure prophylaxis uptake among Spanish-speaking transgender women: a randomized controlled trial in North and South Carolina, 2019–2022. Am J Public Health. 2024;114(1):68–78.CrossRefPubMedPubMedCentral
38.
Sevelius JM, Glidden DV, Deutsch M, et al. Uptake, retention, and adherence to pre-exposure prophylaxis (PrEP) in TRIUMPH: a peer-led PrEP demonstration project for transgender communities in Oakland and Sacramento. California J Acquir Immune Defic Syndr. 2021;88(S1):S27-s38.CrossRefPubMed
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
Bourdeau B, Shade S, Koester K, et al. Implementation science protocol: evaluating evidence-informed interventions to improve care for people with HIV seen in Ryan White HIV/AIDS program settings. AIDS Care. 2021;33(12):1551–9.CrossRefPubMed
51.
52.
Marc LG, Goldhammer H, Mayer KH, et al. Rapid implementation of evidence-informed interventions to improve HIV health outcomes among priority populations: the E2i initiative. Public Health Rep. 2022;137(4):617–24.CrossRefPubMed
Metadata
Title
Identifying Effective Strategies for Improving Engagement in HIV Prevention and Care Among Transgender Persons in the United States: A Systematic Review
Authors
Nicole Crepaz
Olivia Peters
Darrel H. Higa
Mary M. Mullins
Charles B. Collins
Publication date
04-09-2024
Publisher
Springer US
Published in
AIDS and Behavior
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-024-04473-1

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