A rare case of thrombotic thrombocytopenic purpura during HEV viremia in an elderly patient. Lymphoplasmapheresis plus rituximab contributed to platelet recovery.
Expanding chronic hepatitis B treatment indications could reduce the risk of liver-related complications, be cost-effective, and simplify care pathways, but should a treat-all approach be adopted?
Interim data from the ATTENTION trial support the use of antiviral therapy in people with chronic hepatitis B who have moderate or high viremia and a normal or mildly elevated ALT concentration.
This review considers the issues surrounding the stage criteria for chronic HBV infection and proposes revisions that may reduce the number of patients in the ‘uncertain stage’ or ‘gray zone’.
Liver disease is often accompanied by cutaneous manifestations. Early identification of these manifestations is key for timely diagnosis and management of the underlying cause.
A rare case of thrombotic thrombocytopenic purpura during HEV viremia in an elderly patient. Lymphoplasmapheresis plus rituximab contributed to platelet recovery.
An immunocompetent man with no history of gastrointestinal disease presented to the emergency department after passing loose stools four times a day for three days. What was the unexpected cause of his symptoms?
Changing to a ciclosporin-based regimen resolved the signs and symptoms of hepatitis in a patient who presented with icterus, weakness, and lethargy two weeks after kidney transplantation and initiation of tacrolimus.
Disseminated intravascular coagulation (DIC) is a complex condition with diverse etiologies. While its association with sepsis has been widely studied, less focus has been given to DIC arising from other critical conditions, such as trauma, burns …
Mac-2 binding protein glycosylation isomer (M2BPGi) is a liver fibrosis biomarker that originated in Japan and has been covered by health insurance for 10 years. M2BPGi is useful not only for liver fibrosis stage prediction but also for assessment …
Developing associations between pathologies affecting different organ systems can ultimately help diagnosticians to broaden differential diagnostics. Liver disease, whether congenital or acquired, can result in several manifestations in the eye.
Liver diseases in pregnancy can be specific to gestation or only coincidental. In the latter case, the diagnosis can be difficult. Rapid diagnosis of maternal-fetal emergencies and situations requiring specialized interventions are crucial to …
Original Article―Liver, Pancreas, and Biliary Tract
IgG4-related disease (IgG4-RD) is a chronic, multisystemic inflammatory disorder that can affect multiple organs simultaneously or heterogeneously [ 1 ]. IgG4-RD is characterized by elevated serum IgG4 levels and the presence of enlarged, nodular …
Multiple sclerosis (MS) is a chronic, inflammatory demyelinating autoimmune disease that affects the central nervous system, leading to varying degrees of physical and cognitive impairment. Patients with relapsing–remitting MS are often treated …
Cytomegalovirus (CMV) infection or reactivation in immune-compromised individuals can lead to a wide range of severe complications including hepatitis. However, its relation with immune checkpoint inhibitors (ICIs) induced hepatitis …
The introduction of immunotherapy has markedly improved the prognosis for cancer patients. Diverging from traditional cancer therapies, it represents an innovative approach that dynamically modulates the immune system on multiple fronts 1 . Central …
A rare case of thrombotic thrombocytopenic purpura during HEV viremia in an elderly patient. Lymphoplasmapheresis plus rituximab contributed to platelet recovery.
