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Single-stage laparotomy for intracardiac leiomyomatosis without open-heart surgery: a case report

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Abstract

Background

Intracardiac leiomyomatosis is a rare leiomyoma that originates from the uterus. It can be easily misdiagnosed because of its nonspecific manifestations. In this case, we aim to emphasize the complete resection of the ICL with a single-stage laparotomy.

Case presentation

Here, we report a case of a 36-year-old female who presented with dyspnea and a mobile tumor in the right atrium that was detected in transthoracic echocardiography prior to cosmetic surgery. The results of computed tomography (CT) scan, Cardiovascular magnetic resonance (CMR), and magnetic resonance venography (MRV) revealed a mass in the IVC extending into the right atrium and pelvic veins. One-stage surgery, along with transesophageal echocardiography monitoring, was performed for the patient, and the tumor was resected entirely without the need for open-heart surgery.

Conclusion

This case report suggests that, in selected cases, one-stage surgery through laparotomy for resecting intravenous leiomyomatosis may be a safer and more efficient approach in comparison with the traditional two-stage operation, due to fewer complications. Based on our case, anticoagulant therapy may also be essential to reduce the risk of embolism during this single-stage laparotomy. Further studies are needed to validate the efficacy and safety of this approach.
Title
Single-stage laparotomy for intracardiac leiomyomatosis without open-heart surgery: a case report
Authors
Shiva Sheibani
Massoud Baghai Wadji
Saeid Hosseini
Hamidreza Pouraliakbar
Mahshid Hesami
Seyedeh Fatemeh Hosseini Jebelli
Kamran Roudini
Alireza Rezvani
Azin Alizadehasl
Publication date
24-01-2026
Publisher
BioMed Central
Published in
BMC Cardiovascular Disorders / Issue 1/2026
Electronic ISSN: 1471-2261
DOI
https://doi.org/10.1186/s12872-025-05444-7
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Image Credits
Abstract graphic of layered, concentric circular shapes in bright green, pink, blue, and purple on a dark blue background. The rings and segments form a complex radial pattern without text/© Springer Health+ IME