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Neurology Headache

Headache

Neuromodulation for headache in pregnancy

Managing headache disorders during pregnancy is challenging due to a known risk of teratogenicity or unknown risks of drug therapies. Can neuromodulatory devices offer a safe and effective alternative?

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Editor's Choice

Migraine in men

Men are under-represented in clinical migraine research and may be underdiagnosed. Discover the unique characteristics of migraine in men, including symptoms, treatment responses, comorbidities, and pain perception.

Empty sella syndrome: an update

Empty sella is generally an incidental radiological finding, but when endocrine, neurological, ophthalmological, or psychiatric symptoms occur empty sella syndrome must be promptly diagnosed.

RCVS linked to methylphenidate

The first case of reversible cerebral vasoconstriction syndrome in which methylphenidate, a drug with vasoconstrictive properties, is the only suspected drug.

Combining treatments for migraine prophylaxis

Combining oral conventional prophylactics, onabotulinumtoxin A, anti-CGRP monoclonal antibodies, and gepants offers a promising approach to target multiple pathways in migraine, potentially enhancing efficacy and tolerability.

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Keynote webinar | Spotlight on sleep in brain health

  • Webinar | 02-05-2024 | 17:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.

Dr. Rolf Fronczek
Dr. Renata Riha
Dr. Sven Rupprecht
Developed by: Springer Medicine
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Case Studies

RCVS linked to methylphenidate

The first case of reversible cerebral vasoconstriction syndrome in which methylphenidate, a drug with vasoconstrictive properties, is the only suspected drug.

Cerebral artery vasoconstriction after migraine treatment

A 40-year-old patient with high-frequency episodic migraine with visual aura developed numbness in her right extremities and face 10 min after a loading dose of galcanezumab.

Brain abscesses from nocardiosis in an immunocompetent patient

Nocardia infection primarily affects immunocompromised patients and brain abscess is rare. But N. beijingensis is an emerging pathogen in immunocompetent individuals and abscess formation appears to be a common manifestation.

Episode 4: Stem cell therapy for PD

A new era for managing Parkinson’s disease?

STEM-PD, the first in-human safety trial of stem cell therapy for Parkinson’s disease, began this year and marks a huge step forward for this type of treatment.

We talk to Prof. Malin Parmar about why stem cell therapy is such a good option for patients with Parkinson’s disease and get an update on the current status of the trial.

Dr. Malin Parmar
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Current Reviews

Zavegepant nasal spray in the acute treatment of migraine: a profile of its use

Zavegepant nasal spray (ZAVZPRET®) is the first intranasal calcitonin gene-related peptide (CGRP) receptor antagonist approved in the USA for the acute treatment of migraine with or without aura in adults. It is a valuable option for these …

Prevalence, Treatment, and Unmet Needs of Migraine in the Middle East: A Systematic Review

Migraine is a neurological disorder characterized by recurrent attacks of headaches of varying severity that may impose a substantial impact on patients' quality of life (QoL). The World Health Organization ranks migraine as a leading cause of …

Safety and efficacy of galcanezumab in chronic and episodic migraine patients: a systematic review and meta-analysis of randomized controlled trials

Migraine is one of the worldwide debilitating neurological disorders which affects many aspects of a patient’s lifestyle [ 1 , 2 ]. According to the US government health survey, in 2018, 40% of US adults had migraine with more than 4.3 million …

Assessing the effectiveness of greater occipital nerve block in chronic migraine: a systematic review and meta-analysis

Among headache disorders, migraine is particularly ranked second worldwide in terms of disability and is the leading cause of disability among young women, according to the Global Burden of Disease 2019 data [ 1 ]. Recent findings indicate that the …

Further Reading

Three-year treatment with anti-CGRP monoclonal antibodies modifies migraine course: the prospective, multicenter I-GRAINE study

  • Open Access
  • Migraine
  • Original Research

Migraine is a highly disabling neurological disorder that, if untreated or poorly managed, can result in a sustained increase in frequency, severity, or both—a phenomenon known as migraine progression [ 1 , 2 ]. Minimizing the risk of migraine …

Impact of Headache and Over-the-Counter Treatment on Pain and Functional and Cognitive Parameters: A Real-World Study across Three Geographies

  • Open Access
  • Headache
  • ORIGINAL RESEARCH

Headache disorders present diverse phenotypes, each characterized by distinct clinical features. The International Classification of Headache Disorders (ICHD-3) divides headache disorders into primary and secondary categories, encompassing various …

US Real-World Effectiveness, Tolerability, and Healthcare Resource Utilization After Addition of Fremanezumab for Preventive Treatment in Patients Using Gepants for Acute Treatment of Migraine: Results From a Retrospective Chart Review

Migraine is one of the most prevalent diseases worldwide, affecting more than 1 billion people globally and resulting in the second most disability-adjusted life years behind lower back pain [ 1 , 2 ]. Many migraine medications are used to reduce …

Clinical Pharmacokinetics of Atogepant in Healthy Japanese and White Adults

Migraine is a chronic neurological disease characterized by attacks of throbbing, unilateral headache of moderate to severe pain [ 1 , 2 ]. It is often associated with nausea, vomiting, photophobia, and phonophobia. Migraine attacks can …

Related topics

Neuromodulation for headache in pregnancy

Managing headache disorders during pregnancy is challenging due to a known risk of teratogenicity or unknown risks of drug therapies. Can neuromodulatory devices offer a safe and effective alternative?

Read more