Mild cognitive impairment, dementia, and affective disorders are the most common and debilitating non-motor symptoms in PD. Here are the DGN's recommendations on diagnosis and treatment.
An unusual case of heart failure caused by ten years of anti-vascular endothelial growth factor treatment for polypoidal choroidal vasculopathy. The HF resolved after cessation of anti-VEGF injections.
Maintaining glycated hemoglobin levels within target range may reduce the risk for developing Alzheimer’s disease and related dementias in older men with diabetes.
The use of diabetes therapeutic technology is being advocated for older people, but what are the benefits and challenges of implementing technology solutions in older individuals with diabetes?
Halving the dose of edoxaban (from 60mg to 30mg) significantly reduces major bleeding events without increasing ischemic events in people with atrial fibrillation aged 80 years or older.
Updated recommendations from DGN on the diagnosis and therapeutic management of impulse control disorders, psychosis, and delirium associated with Parkinson’s disease.
Dapagliflozin significantly improves pulmonary vascular load and right ventricular function during exercise in people with heart failure with preserved ejection fraction.
What is the evidence for testosterone therapy in men with functional hypogonadism? Can it address weak guideline recommendations and historic concerns about long-term safety?
Diabetic neuropathy is a frequent complication of diabetes. With no treatments targeting the underlying mechanisms, strategies focus on preventative care and pain management.
Apixaban is associated with lower rates of major hemorrhagic events than rivaroxaban or warfarin in patients with cirrhosis and nonvalvular atrial fibrillation.
GLP-1 receptor agonists are not linked to an increased risk for suicidal thoughts or actions versus SGLT-2 or DPP4 inhibitors in older adults with type 2 diabetes.
Diagnosing myasthenic crisis with atypical presentation is very challenging, especially in elderly patients who can present with isolated dysarthria, suggesting lacunar stroke.
Left bundle branch area pacing, which captures the left conduction system and progresses along the Purkinje system, is a novel pacing technique that shows promise. However these two cases describe procedural complications to be wary of.
How do aging-related diseases impact older transgender individuals? Beyond the inherent risk of chronic disease, there is a cognitive and psychiatric risk, and a reluctance to adhere to screening programs.
Latest advice from DGN, in collaboration with ÖGN and SNG, on diagnostics, pharmacotherapy, and invasive treatment options to manage motor and non-motor symptoms.
A clinical practice guideline on the management of foot and ankle pathologies caused by rheumatoid arthritis, covering orthoses, therapeutic footwear, surgery, and self-care strategies and education.
Statin therapy in individuals aged 75 years and older reduces the risk for CV diseases and all-cause mortality, with benefits persisting in those aged 85 years and older.
