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Annals of Surgical Oncology
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28-09-2024 | Genetic Testing | ASO Author Reflections

ASO Author Reflections: Mainstream Genetic Testing Makes It Feasible for a Large Integrated System to Expand the Testing Eligibility in Breast Cancer

Authors: Veronica Shim, MD, Audrey Karlea, MS, LCGC, Laurel Habel, PhD

Published in: Annals of Surgical Oncology | Issue 1/2025

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Excerpt

The guidelines for multigene panel germline testing for hereditary cancer in patient with early breast cancer have continued to change and expand eligibility recommendations. In 2019, the National Comprehensive Cancer Network recommended testing all patients diagnosed under < 45 years.1 In early 2024, Society of Surgical Oncology/American Society of Clincial Oncology joint guidelines recommended universal genetic testing for patients with breast cancer ≤ 65 years.2 …
Literature
1.
National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology–Genetic/familial high-risk assessment: breast, ovarian, and pancreatic. Version 3; 2019.
2.
Bedrosian I, Somerfield MR, Achatz MI, Boughey JC, Curigliano G, Friedman S, Kohlmann WK, Kurian AW, Laronga C, Lynce F, Norquist BS, Plichta JK, Rodriguez P, Shah PD, Tischkowitz M, Wood M, Yadav S, Yao K, Robson ME. Germline testing in patients with breast cancer: ASCO-society of surgical oncology guideline. J Clin Oncol. 2024;42(5):584–604. https://​doi.​org/​10.​1200/​JCO.​23.​02225.CrossRefPubMed
3.
Metadata
Title
ASO Author Reflections: Mainstream Genetic Testing Makes It Feasible for a Large Integrated System to Expand the Testing Eligibility in Breast Cancer
Authors
Veronica Shim, MD
Audrey Karlea, MS, LCGC
Laurel Habel, PhD
Publication date
28-09-2024
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 1/2025
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-024-16311-8

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