Skip to main content
Top

Open Access 06-06-2025 | General Anesthesia | CLINICAL INVESTIGATION

CT-Guided Percutaneous Cryoablation of Small Renal Masses: General Anesthesia Versus Conscious Sedation with Dexmedetomidine

Authors: Theresa Junker, Nina Stage, Mie Gaedt Thorlund, Benjamin Schnack Brandt Rasmussen, Bo Redder Mussmann, Tommy Kjærgaard Nielsen, Jakob Kjersgaard Johansen, Ole Graumann

Published in: CardioVascular and Interventional Radiology

Login to get access

Abstract

Purpose

General anesthesia (GA) is often used during CT-guided percutaneous cryoablation (PCA) of renal tumors. This retrospective study compared GA to conscious sedation (CS), with dexmedetomidine and remifentanil, regarding theater time and hospital stay during PCA of renal tumors.

Materials and Methods

This retrospective study reviewed 350 patients treated with PCA between January 1, 2015, and December 31, 2019. Associations were analyzed between the type of anesthesia and theater time, hospital stay, complications, and clinical outcomes.

Results

The cohort consisted of 148 patients who received PCA in GA (mean age 64.7 ± 13.4 years; 99 men) and 202 patients who received PCA in CS (mean age 66.7 ± 10.7 years; 142 men). Patients in the GA group had significantly longer theater times (mean 2.6 h ± 0.48) compared to their CS counterparts (mean 2.1 h ± 0.46; p < 0.001). Furthermore, the median length of hospital stay was significantly longer in the GA group (8.5 vs. 5.5 h, p < 0.001). In addition, patients in the GA group had significantly lower levels of consciousness in the recovery room compared to the CS group (p = 0.047). There were no differences between the groups regarding complications, graded on the CIRSE classification system (p = 0.463), or rate of incomplete ablation at three-month follow-up (p = 0.229).

Conclusion

Patients who undergo PCA of renal tumors under CS have significantly shorter theater time and length of hospital stay compared to patients who undergo PCA in GA, with no impact on complications or technical failure rate.

Level of Evidence

3, a retrospective cohort study.
Literature
This content is only visible if you are logged in and have the appropriate permissions.
Metadata
Title
CT-Guided Percutaneous Cryoablation of Small Renal Masses: General Anesthesia Versus Conscious Sedation with Dexmedetomidine
Authors
Theresa Junker
Nina Stage
Mie Gaedt Thorlund
Benjamin Schnack Brandt Rasmussen
Bo Redder Mussmann
Tommy Kjærgaard Nielsen
Jakob Kjersgaard Johansen
Ole Graumann
Publication date
06-06-2025
Publisher
Springer US
Published in
CardioVascular and Interventional Radiology
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-025-04079-7

How can your team use biomarkers to improve management of AD? (Link opens in a new window)

Our experts explore using biomarker tests and interpreting results, establishing a shared decision-making approach with patients and caregivers, and applying biomarker testing to guide treatment strategies.

This content is intended for healthcare professionals outside of the UK.

Supported by:
  • Lilly
Developed by: Springer Health+ IME
Register your interest

How can you integrate PET into your practice? (Link opens in a new window)

1.5 AMA PRA Category 1 Credit(s)™

PET imaging is playing an increasingly critical role in managing AD. Our expert-led program will empower you with practical strategies and real-world case studies to effectively integrate it into clinical practice.

This content is intended for healthcare professionals outside of the UK.

Supported by:
  • Lilly
Developed by: Springer Health+ IME
Register your interest