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Published in: Current Psychiatry Reports 12/2018

01-12-2018 | Sex and Gender Issues in Behavioral Health (CN Epperson and L Hantsoo, Section Editors)

Gender-Affirming Hormone Use in Transgender Individuals: Impact on Behavioral Health and Cognition

Authors: Hillary B. Nguyen, Alexis M. Chavez, Emily Lipner, Liisa Hantsoo, Sara L. Kornfield, Robert D. Davies, C. Neill Epperson

Published in: Current Psychiatry Reports | Issue 12/2018

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Abstract

Purpose of Review

With increasing numbers of transgender and gender non-binary individuals presenting for care, knowing how to elucidate the mental health and cognitive outcomes of gender-affirming hormone therapy (GAHT) is necessary. This article reviews the present literature covering GAHT effects on mood, behavioral health, and cognition in these individuals and offers research priorities to address knowledge gaps.

Recent Findings

Although there are some conflicting data, GAHT overwhelmingly seems to have positive psychological effects in both adolescents and adults. Research tends to support that GAHT reduces symptoms of anxiety and depression, lowers perceived and social distress, and improves quality of life and self-esteem in both male-to-female and female-to-male transgender individuals.

Summary

Clinically, prescribing GAHT can help with gender dysphoria-related mental distress. Thus, timely hormonal intervention represents a crucial tool for improving behavioral wellness in transgender individuals, though effects on cognitive processes fundamental for daily living are unknown. Future research should prioritize better understanding of how GAHT may affect executive functioning.
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Metadata
Title
Gender-Affirming Hormone Use in Transgender Individuals: Impact on Behavioral Health and Cognition
Authors
Hillary B. Nguyen
Alexis M. Chavez
Emily Lipner
Liisa Hantsoo
Sara L. Kornfield
Robert D. Davies
C. Neill Epperson
Publication date
01-12-2018
Publisher
Springer US
Published in
Current Psychiatry Reports / Issue 12/2018
Print ISSN: 1523-3812
Electronic ISSN: 1535-1645
DOI
https://doi.org/10.1007/s11920-018-0973-0

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