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Esophagus and Gastrointestinal Tract Gastrointestinal Microbiota

Gastrointestinal Microbiota

Prebiotics, probiotics, and postbiotics: an emerging approach to MetS

Biotics have the potential to improve metabolic syndrome by reducing weight gain, insulin resistance, dyslipidemia, inflammation, and improving glycemic control and gut barrier function.

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Editor's Choice

Add-on FMT shows promise in multiple cancers

Three trials point to the potential of fecal microbiota transplantation to enhance the efficacy of immune checkpoint inhibitor-based therapy in people with cancer.

MDR bacteria decolonization strategies for the GI tract

Nonabsorbable antimicrobials have shown limited efficacy in the eradication of multidrug resistant bacteria in the GI tract. This review outlines current and novel strategies, including live biotherapeutic products and FMT, as well as knowledge gaps.

Bacterial contributions to oncogenesis

From the mechanistic contributions of pathogenic bacteria to tumor initiation, to the role dysbiosis plays in influencing systemic cancer behavior, understand the impact bacteria has as a driver of cancer development.

Cyclic EEN supports drug-free remission in children with Crohn's disease

Cyclic exclusive enteral nutrition offers greater long-term remission rates than continuous partial enteral nutrition in children with Crohn's disease who have responded to nutritional induction therapy.

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Episode 9: The gut microbiome and CAR T-cell therapy

How do nutrition, supplements and antibiotics impact patient outcomes?

Recent research suggests that the gut microbiome could be an important modulator of response to CAR T-cell therapy in patients with hematologic cancers.

Prof. Marion Subklewe takes us through the latest evidence, highlighting the impact of antibiotics, nutrition, and dietary supplements, and discusses how to devise interventions to improve patient outcomes.

Prof. Marion Subklewe
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Podcast

Current Reviews

Mechanisms of exercise in preventing cardiovascular diseases: Insights from gut microbiota characteristics in pathological states of cardiovascular diseases

Cardiovascular diseases (CVD) are major lethal diseases worldwide. Imbalance of gut microbiota (GM) homeostasis affects the development and progression of CVD. Exercise can remodel GM and improve GM disorders in CVD patients. By combing the …

Further Reading

A randomized open label pilot study evaluating the efficacy of two dosing regimens of rifamycin SV MMX in the treatment of small intestinal bacterial overgrowth

Antibiotics have demonstrated efficacy in the eradication of the underlying overgrowth bacteria and improvement of symptoms of small intestinal bacterial overgrowth (SIBO). The use of standard antibiotics may cause intolerable side effects such as …

Effect of gut microbiota changes on cytokines IL-10 and IL-17 levels in liver transplantation patients

Liver transplantation (LT) is a critical intervention for individuals with end-stage liver disease, offering a potential remedy for liver failure, cirrhosis, and other chronic hepatic disorders. Despite significant advancements in surgical …

Mechanisms of exercise in preventing cardiovascular diseases: Insights from gut microbiota characteristics in pathological states of cardiovascular diseases

Cardiovascular diseases (CVD) are major lethal diseases worldwide. Imbalance of gut microbiota (GM) homeostasis affects the development and progression of CVD. Exercise can remodel GM and improve GM disorders in CVD patients. By combing the …

Image Credits
Foods to support a healthy digestive system/© fcafotodigital / e+ / Getty Images, Artistic rendering of fecal microbiota transplantation pills/© mbruxelle / Stock.adobe.com, Intestinal microbiota/© (M) Tatiana Shepeleva / stock.adobe.com, Malignant cancer cells/© koto_feja / Getty Images / iStock, Boy talking with doctor/© Inside Creative House / Getty Images / iStock (symbolic image with models), Medicine Matters Podcast promo image/© Springer Medizin GmbH, Conceptual illustration of gut microbiome/© ArtemisDiana / Getty Images / iStock