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Obesity Surgery

05-11-2024 | Gastroesophageal Reflux Disease | Review

Efficacy of One-Anastomosis Gastric Bypass Versus Roux‐en‐Y Gastric Bypass for Gastroesophageal Reflux Disease: A Systematic Review and Meta‐analysis of Randomized Controlled Trials

Authors: Nikolaos Kapellas, Samer Alkhalil, Metin Senkal

Published in: Obesity Surgery

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Abstract

This study aimed to investigate the efficacy of one-anastomosis gastric bypass (OAGB) on gastroesophageal reflux disease (GERD) compared with Roux-en-Y gastric bypass (RYGB) in patients with obesity. Three databases (Medline, Cochrane Central, and Scopus) were searched for relevant articles published until August 12, 2024. A total of nine randomized controlled trials, including 643 patients, were selected. OAGB was statistically significantly associated with a higher risk of GERD than RYGB (OR = 3.14, 95% CI 1.23–8.03, p < 0.05). The odds for de novo GERD after OAGB are almost six times higher than after RYGB (OR = 5.65, 95% CI 1.53–20.82, p < 0.05). RYGB has a lower incidence of de novo GERD cases and is more effective than OAGB in reducing GERD.
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Metadata
Title
Efficacy of One-Anastomosis Gastric Bypass Versus Roux‐en‐Y Gastric Bypass for Gastroesophageal Reflux Disease: A Systematic Review and Meta‐analysis of Randomized Controlled Trials
Authors
Nikolaos Kapellas
Samer Alkhalil
Metin Senkal
Publication date
05-11-2024
Publisher
Springer US
Published in
Obesity Surgery
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-024-07571-0
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